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Acceptability of and Preferences for Long-Acting Injectable HIV PrEP and Other PrEP Modalities among Sexual Minority Men in Nigeria, Africa

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Abstract

Sexual minority men (SMM) in Nigeria have been disproportionately affected by HIV. Pre-exposure prophylaxis (PrEP) reduces risk for HIV acquisition among SMM by over 90%. The current study investigated the association between demographics, socioeconomic marginalization, sexual health and willingness to use long-acting injectable (LAI-) PrEP and preferences for other PrEP modalities in a sample of HIV-negative SMM in Nigeria. Between March and June 2019, SMM residing in Abuja, Delta, Lagos, and Plateau completed a quantitative survey. To examine willingness to use LAI-PrEP and PrEP modality preferences, multivariable binomial and multinomial logistic regression models were fit. We found that 88% were willing to use LAI-PrEP and 44% preferred LAI-PrEP to other PrEP modalities. Participants who reported interest in LAI-PrEP were more likely to be single, engage in inconsistent condom use, and report having a primary care provider. Compared to participants who preferred daily oral PrEP, participants who preferred other PrEP modalities had higher odds of having some university education/university degree or higher and reporting low financial hardship. It is imperative that SMM in Nigeria are prioritized for access to new HIV prevention interventions, as they bear a disproportionate burden of HIV and are especially vulnerable to HIV infection.

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Acknowledgements

This work was supported by grant R36 DA047216 from the National Institute on Drug Abuse (PI: Adedotun Ogunbajo), and the Robert Wood Johnson Health Policy Research Scholars Program. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. We will like to thank all the participants of the study for their time and efforts. We would also like to thank the staff at Centre for Right to Health (Abuja) Equality Triangle Initiative (Delta), Improved Sexual Health and Rights Advocacy Initiative (ISHRAI, Lagos) and Hope Alive Health Awareness Initiative (Plateau).

Funding

This work was supported by grant R36 DA047216 from the National Institute on Drug Abuse and the Robert Wood Johnson Health Policy Research Scholars Program.

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Authors and Affiliations

  1. Department of Epidemiology, Harvard T.H. Chan School of Public Health, , 677 Huntington Ave., Sixth Floor, Boston, MA, 02115, USA

    Adedotun Ogunbajo

  2. Harvard Center for Population and Development Studies, Cambridge, MA, USA

    Alexander C. Tsai

  3. Massachusetts General Hospital, Boston, MA, USA

    Alexander C. Tsai

  4. Harvard Medical School, Boston, MA, USA

    Alexander C. Tsai & Kenneth H. Mayer

  5. Department of Immunology, Harvard T.H. Chan School of Public Health, Boston, MA, USA

    Phyllis J. Kanki

  6. Beth Israel Deaconess Medical Center, Boston, MA, USA

    Kenneth H. Mayer

  7. Fenway Health, Boston, MA, USA

    Kenneth H. Mayer

Authors
  1. Adedotun Ogunbajo
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  2. Alexander C. Tsai
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  3. Phyllis J. Kanki
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  4. Kenneth H. Mayer
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Correspondence to Adedotun Ogunbajo.

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ACT reports receiving a financial stipend from Elsevier, Inc. for his work as Co-Editor in Chief of the journal SSM-Mental Health.

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Ogunbajo, A., Tsai, A.C., Kanki, P.J. et al. Acceptability of and Preferences for Long-Acting Injectable HIV PrEP and Other PrEP Modalities among Sexual Minority Men in Nigeria, Africa. AIDS Behav 26, 2363–2375 (2022). https://doi.org/10.1007/s10461-022-03575-y

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