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Re-Engagement into HIV Care: A Systematic Review

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Abstract

Identifying evidence-based interventions that can optimize the re-engagement into care of people living with HIV is necessary to achieve and sustain HIV epidemic control. We conducted a systematic review of interventions for re-engagement into HIV care to examine the accumulated evidence and to identify similarities and differences across studies. Between January and March 2020, we searched MEDLINE, Embase, CINAHL, and PsycINFO databases for publications from 1996 to 2020. We screened 765 references and selected 125 publications for full-text review. For the nine included studies, the intervention centered on (1) integration of clinic and HIV surveillance data; (2) additional or different levels of support provided by healthcare workers; or (3) multi-component intervention. Irrespective of the interventions, mixed results were found for re-engagement into care or ART re-initiation. None of the studies led to an improvement in viral suppression. Re-engagement in HIV care is critical for longitudinal HIV and national program success. Standardizing definitions for out-of-care and re-engagement would facilitate the comparison of interventions. Rigorous study designs to assess strategies to enhance HIV re-engagement are warranted.

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Acknowledgements

We thank Tyler New for editing the manuscript.

Author information

Author notes

  1. Natalia Blanco and Marie-Claude C. Lavoie have contributed equally to the work.

Authors and Affiliations

  1. Ciheb, Institute of Human Virology, School of Medicine, University of Maryland Baltimore, 725 West Lombard Street, Baltimore, MD, 21201, USA

    Natalia Blanco, Marie-Claude C. Lavoie, David J. Riedel & Kristen A. Stafford

  2. Ciheb—Kenya, Nairobi, Kenya

    Emily Koech

  3. Maryland Global Initiatives Corporation—Kenya, an affiliate of the University of Maryland, Baltimore, Nairobi, Kenya

    Caroline Ngeno

  4. Maryland Global Initiatives Corporation—Nigeria, an affiliate of the University of Maryland, Baltimore, Abuja, Nigeria

    Sylvia Adebajo

  5. Health Services and Human Services Library, University of Maryland Baltimore, Baltimore, USA

    Emilie Ludeman

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Contributions

NB, MCL and KAS designed the study. EL conducted the search strategy. NB and MCL independently assessed records for eligibility and extracted the data. NB and MCL wrote the initial draft of the manuscript. All authors critically reviewed and revised the drafts and approved the final version for publication.

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Correspondence to Natalia Blanco.

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Blanco, N., Lavoie, MC.C., Koech, E. et al. Re-Engagement into HIV Care: A Systematic Review. AIDS Behav 26, 132–146 (2022). https://doi.org/10.1007/s10461-021-03365-y

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