Abstract
Aim
To investigate bone mineral density (BMD) profiles, the prevalence of osteoporosis and its risk factors among adults aged ≥45 years in Liyang, southern Jiangsu Province, China.
Subject and methods
This was a population-based cross-sectional study of adults aged ≥45 years in Liyang City, Jiangsu Province, China. We used multiphase cluster random sampling to register a total of 10,179 participants between October 2019 and November 2020, and 6429 participants were included in the final analyses. All participants completed a questionnaire and underwent BMD measurements. A multivariable logistic regression model was used to examine the risk factors for osteoporosis, and the results were presented as odds ratios (ORs) and 95% confidence intervals (CIs).
Results
Crude prevalence of osteoporosis among all participants was 15.83%. Logistic regression analysis revealed that advanced age (OR = 3.00, 95% CI 2.62–3.42), female sex (OR = 1.53, 95% CI 1.32–1.77), fracture history (OR = 1.33, 95% CI 1.15–1.53), trauma history (OR = 1.50, 95% CI 1.14–1.97), and underweight (body mass index <18.5 kg/m2; OR = 2.08, 95% CI 1.40–3.09) were significantly associated with an increased risk of osteoporosis. Subgroup analysis revealed that female sex and underweight exhibited a combined effect on the risk of osteoporosis (OR = 4.32, 95% CI 2.49–7.49).
Conclusions
The prevalence of osteoporosis was high among middle-aged and elderly people in southern Jiangsu Province, China. Behavioral interventions should focus on underweight women aged ≥45 years to promote healthy lifestyles to prevent the development of osteoporosis.
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Data availability
The data that support the findings of this study are available from Liyang Center for Disease Control and Prevention, but restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available. Data are however available by contacting the corresponding author (e-mail: shenyueping@suda.edu.cn) upon reasonable request of the author and with the permission of the Liyang Center for Disease Control and Prevention.
Code availability
Not applicable.
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Acknowledgements
We are very grateful to all the participants and the staff from Liyang Center for Disease Control and Prevention and The peoples’ Hospital of Liyang City. We also are thankful to those who have critically reviewed this manuscript, and also would like to thank Editage (http://www.editage.cn) for English language editing.
Funding
This work was supported by the National Natural Science Foundation of China (project number 81973143), the Liyang Chronic Disease Risk Factor Monitoring Cohort Study (project number P113911618), and the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).
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Conceptualization, Zhengyu Jiang, Ying Wu, and Yueping Shen; methodology, Zhaolong Feng, Zhengyu Jiang, and Yueping Shen; formal analysis and investigation, Zhaolong Feng, Zhengyu Jiang, Lei Cao, Qida He, Siyuan Liu, Wei Hu, Jiadong Chu, Xuanli Chen; writing–original draft preparation, Zhaolong Feng and Zhengyu Jiang; writing–review and editing, Yueping Shen, Siyuan Liu, Tongxing Li, Qiang Han, Na Sun; funding acquisition, Yueping Shen; supervision, Zhaolong Feng, Zhengyu Jiang, and Yueping Shen. All authors have read and agreed to the published version of the manuscript.
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Feng, Z., Jiang, Z., Cao, L. et al. Prevalence and risk factors associated with osteoporosis among middle-aged and elderly people in southern Jiangsu Province, China. J Public Health (Berl.) (2023). https://doi.org/10.1007/s10389-023-02100-2
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DOI: https://doi.org/10.1007/s10389-023-02100-2