Abstract
Numerical and temporal control of behavior is ubiquitous across many species of animals. Recent studies showed that in the presence of reliable discriminative stimuli, mice ignore temporal relations and probabilistic information but when discriminative stimuli become non-informative, the same mice can spontaneously start relying on previously experienced time intervals and probabilities. Similar dynamics do not readily generalize to counting behavior since the response-outcome contingency functions differ when reinforcement depends on the number vs. timing of responding. In the current study, mice (N = 32) learned to press two different levers 10 (few) or 20 (many) times, while the active lever was signaled by a light stimulus. The probability of the few/many trials was manipulated between groups. During testing, the informative value of light stimulus was eliminated by signaling both few- and many-levers. In a quarter of training trials, mice ignored the discriminative stimulus and adopted a numerical decision strategy (starting to respond on the few-option and then switching to the many-option in many trials) that was sensitive to probabilistic information. The frequency but not the probability-sensitive parametrization of switching behavior changed when the discriminative stimulus became non-informative in testing. These findings suggest that there is a relatively strong representational control over counting behavior even in conditions that afford strong stimulus control.
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Funding
This research was supported by a grant from the Scientific and Technological Research Council of Turkey (TÜBİTAK) to FB [grant number: 117K370]. TÜBİTAK supported PT through the National Scholarship Program for master’s degree students (BİDEB 2210A). This study was the Master’s thesis of PT.
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All authors contributed to the study’s conception and design. PT and EG collected the data. PT and FB ran the statistical analysis and wrote the original draft. PT, EG, and FB reviewed and edited the original draft of the manuscript. All authors read and approved the final manuscript.
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All procedures performed in this study were in accordance with the ethical standards of the institutional and/or national research committee. The study was approved by the Koç University Animal Research Local Ethics Committee (No. 2016.034).
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Toptaş, P., Gür, E. & Balcı, F. Count-based decision-making in mice: numerosity vs. stimulus control. Anim Cogn 25, 1621–1630 (2022). https://doi.org/10.1007/s10071-022-01652-2
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DOI: https://doi.org/10.1007/s10071-022-01652-2