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Comparative study on anti-oxidative and anti-inflammatory properties of hydroponic ginseng and soil-cultured ginseng

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A Correction to this article was published on 28 September 2018

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Abstract

Hydroponic ginseng (HPG) and soil-cultured ginseng (SCG) were extracted in 70% methanol to quantify relative content of 8 ginsenosides and polyphenolic compounds, and flavonoids to compare their antioxidative effects. Level of nitric oxide and inflammatory targets produced in LPS-stimulated RAW 264.7 cells were measured. 2-year-old HPG shoots contained highest levels of ginsenoside Rb2, Rb3, Rd, Re, and F1. Total polyphenol content was highest in shoots of HPG, followed by roots of HPG and SCG. HPG shoots had high radical scavenging activity and an elevated ability to inhibit linoleic acid oxidation. 2-year-old HPG shoots reduced nitric oxide production in RAW 264.7 cells by 47%, whereas 6-year-old SCG roots reduced it by only 21%. HPG also significantly lowered mRNA expression of iNOS, TNF-α, IL-1β, and IL-6, as determined by RT-PCR, compared to SCGs. Therefore, HPG may have potential for utilization as an alternative to SCG, because of superior antioxidant and anti-inflammatory properties.

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  • 28 September 2018

    The original version of this article unfortunately contained a mistake. The presentation of the row “Total (μg/g)” in Table 2 was incorrect.

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Acknowledgements

This research was supported by the Priority Research Centers Program through the National Research Foundation of Korea (NFR) funded by the Ministry of Education, Science and Technology (Grant Number: 2009-0093824).

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Authors and Affiliations

  1. Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea

    Ji Eun Hwang, Dong Hwa Suh, Kee-Tae Kim & Hyun-Dong Paik

  2. Bio/Molecular Informatics Center, Konkuk University, Seoul, 05029, Republic of Korea

    Kee-Tae Kim & Hyun-Dong Paik

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  1. Ji Eun Hwang
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  2. Dong Hwa Suh
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Correspondence to Hyun-Dong Paik.

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The original version of this article was revised: The presentation of the row “Total (μg/g)” in table 2 was incorrect.

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Hwang, J.E., Suh, D.H., Kim, KT. et al. Comparative study on anti-oxidative and anti-inflammatory properties of hydroponic ginseng and soil-cultured ginseng. Food Sci Biotechnol 28, 215–224 (2019). https://doi.org/10.1007/s10068-018-0450-x

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