Introduction

Osteoarthritis (OA) is the most common degenerative joint disease with an inflammatory component that starts from the matrix of the articular cartilage, progresses with disruption of chondrocyte responses and results in tissue destruction. In OA, primary involvement is seen in the articular cartilage, and progressive damage occurs. However, although the articular cartilage is initially affected, the synovial membrane, subchondral bone, ligaments, joint capsule and periarticular muscles are also affected in the later stages. These degenerative changes in the pathophysiology of the disease make OA an important cause of disability [1,2,3,4]. It has been reported that approximately 250 million people worldwide suffer from OA. Among them, the prevalence of knee OA (KOA) is the highest, with 16–17% in the population aged 50 to 75 years [5]. Moreover, KOA is one of the five leading causes of disability in adults over 50. Therefore, it is a significant threat to patients’ quality of life (QoL) and independence [6].

Joint pain is considered the main cause of functional impairment and disability in patients with KOA [7]. However, OA patients suffer from a range of extra-articular symptoms which also leads to functional impairment and disability such as fatigue, depression, anxiety, fear of movement, physical inactivity, and decreased muscle strength [8,9,10,11,12]. As a result of all these symptoms, the QoL of patients with KOA deteriorates [13]. To address these issues and control the progression of OA, lifestyle modification is one of the effective strategies universally recommended in OA guidelines. Lifestyle modification includes physical exercises, self-management, and efficient learning of OA-related information [14].

Physical exercises play an important role in balancing cytokine dynamics in synovial fluid, inhibiting inflammatory reactions and oxidative stress [5]. Over the past 15 years, numerous studies have emerged supporting the beneficial effects of exercise in the treatment of KOA [15,16,17]. In many randomized controlled trials, the use of muscle strengthening and range-of-motion exercises has been observed to reduce pain and improve function in people with KOA, even with only moderate adherence to exercise [18,19,20]. KOA management with exercise is recognized as the cornerstone of conservative and self-treatment for this chronic disease [17]. However, applying a lifestyle modification strategy to individuals with KOA upon discharge from the healthcare setting remains a challenge [21]. The lack of professional supervision and feedback will result in reduced participation in continuing OA medical or rehabilitative services, which in turn will reduce the effectiveness of OA treatments [22]. In addition, studies have found that very few medical facilities and resources can be accessed in rural areas where the health-related QoL of the elderly is reported to be low [23].

With the development of telemedicine, it has been determined that patients living in remote areas have the chance to communicate with professional physicians simultaneously. The concept of telerehabilitation has been introduced in the field of physical medicine and rehabilitation, which combines telemedicine and rehabilitation interventions to support ongoing rehabilitation services for patients [24]. Internet-based rehabilitation is one of the effective strategies in telerehabilitation. The use of the internet to provide health-related interventions has the potential to reduce the cost of treatment and improve user satisfaction. There are many barriers to patient face-to-face care, such as distance, cost of travel, length of absence from work, and limited access to healthcare providers in rural areas [25]. In addition to these obstacles, the necessity of social isolation due to circumstances such as the recent Covid-19 pandemic restricts patients from receiving face-to-face treatment. However, these obstacles can be overcome with internet-based treatment systems.

The optimal design of modules related to lifestyle modification in internet-based rehabilitation programs has been taken into account in patients with KOA as in other diseases. In order to investigate the feasibility and effectiveness of internet-based rehabilitation in individuals with KOA, many studies have been conducted in which internet-based applications such as “Join2Move,” “PainCOACH,” and “Help My Knees” are included in treatment programs, as well as treatment applications via message, e-mail, and video [26,27,28]. The results of some of these studies suggest that the internet can be used successfully as a tool to provide self-management and rehabilitation interventions to patients with KOA. It has been reported that pain, stiffness, and fatigue are reduced, and physical activity, function, mood, and QoL are improved in individuals who receive individualized and interactive treatment. It was also stated that patients were satisfied with the internet-based treatment approach [29]. However, the effectiveness of telerehabilitation in patients with KOA differs in studies due to reasons such as ensuring compliance with internet-based rehabilitation, education level, and willingness of the participants, whether remote control reminders such as e-mail, telephone, or text were set up during the research and so on [27]. Studies evaluating these parameters have been conducted in many countries such as China, Australia, Canada, South Korea, Denmark, Spain, America, and Germany [29].

Considering the development of technology and the conditions of the pandemic period, it is important to evaluate the acceptability, feasibility, and compliance of telerehabilitation in different populations for patients with KOA in order to determine telerehabilitation results in a universal way. In studies on telerehabilitation in patients with KOA, the level of patients’ satisfaction with the treatment was evaluated. Yet, there is no study in the literature in which the quality of the physiotherapy and rehabilitation program applied to the patient is evaluated by the patient. Besides, also, there is no study in the literature that includes a simultaneous treatment program for patients with KOA, accompanied by a physiotherapist, via video conference. This study was planned to fill these gaps in the literature. Therefore, the aim of this study was to examine the effects of simultaneous telerehabilitation with a physiotherapist in patients with KOA and to evaluate the quality of the physiotherapy and rehabilitation program received through telerehabilitation.

Materials and methods

Trial design

The present study was approved by the Research Ethics Committee of a university. It is a randomized controlled trial and carried out according to the Declaration of Helsinki [30]. All patients provided online informed consent.

Participants

Patients diagnosed with mild to moderate KOA by their physicians according to both the American College of Rheumatology (ACR) Clinical and Radiographic Classification Criteria were recruited [31]. The radiographs were procured as part of the patients’ routine care; they were not exclusive to this study. Additional inclusion criteria comprised being a volunteer to participate in the study; living independently; being able to walk without using an assistive device; owning a mobile phone, tablet, or computer with an internet connection; and being able to use the device without assistance. Exclusion criteria involved having been diagnosed with any other systemic rheumatic diseases, having been involved in a physiotherapy and rehabilitation program in any health institution in the last 6 months, having knee-related surgery, having meniscal or ligament-associated tears occurred in the past 6 months, having answered yes to at least 1 of the first 7 questions of the Physical Activity Readiness Questionnaire for Everyone [32], having a history of falling more than 2 times in the last 6 months, having a history of knee injection in the last 4 weeks or scheduled in the next 8 week, being illiterate, having cognitive problems, having blurred vision problem, and having hearing loss.

Procedure

The patients who were informed and eligible for the study were randomized into the treatment and control groups through a randomization program. For the patients in the treatment group, telerehabilitation was performed using the Zoom Meetings application, via video conference simultaneously, accompanied by a physiotherapist. The patients in the control group were given a brochure showing how to do the exercises and explaining how to do each exercise.

Participants were informed about how to download the free Zoom Meetings application where the physical performance test for both groups and treatment for the telerehabilitation group will be held. In addition, the meeting identification number and passcode required to attend the Zoom meeting were sent to the participants via message. While the patients in the control group used the Zoom Meetings application only during the evaluation on the baseline and after 8 weeks, the patients in the treatment group used it 24 times in total for telerehabilitation, excluding their evaluations. Additionally, patient education was given to each patient after the evaluation via Zoom Meetings application.

The treatment was the same for both groups and included knee extension, knee flexion, and hip flexion in sitting position; chair sit-up; isometric contraction of quadriceps and hip adductor muscles and straight leg raise in supine position; hip abduction and adduction in the side-lying position; narrow and wide angle squats and standing on one leg in the standing position. Moreover, after completing all these exercises, hamstring stretching while sitting in a chair and quadriceps stretching exercises in the side-lying position were performed. The duration and repetitions of these exercises were increased on a weekly basis. Telerehabilitation was carried out 3 days a week, for 45–60 min a day and for 8 weeks, with a physiotherapist. Patients in the control group did these exercises on their own.

Clinical outcome measures

Clinical outcomes were measured at baseline and after 8 weeks treatment. Only a physical performance test (30-s chair stand test) was assessed via Zoom Meetings application by a physiotherapist. Other outcomes including demographic features were evaluated using online questionnaires.

30 CST

This physical performance test was used to evaluate lower extremity muscle strength and dynamic balance. The individual sits on a chair with no arm support, back support, and an average height of 44 cm from the floor. The back of the chair is against the wall so that it does not slide during the test process. When the individual sits on the chair, it is recommended that the feet be further back than the knee joint so that their feet touch the ground and can sit and stand up faster. Within the framework of the instructions, it is ensured that the individual crosses his arms over his shoulders and makes two attempts. By keeping time with a stopwatch, the learner is asked to sit and stand for 30 s, and the score obtained is recorded in the evaluation form as the number of repetitions. During the test, care is taken to ensure that the individual is without shoes [33].

Physical Activity Readiness Questionnaire for Everyone

The questionnaire contains a total of 48 questions, including 7 preliminary questions and 10 additional questions (with 41 subdomains). The answers consist of yes and no options. Physicians do not see any inconvenience in making individuals who answer “no” to all of the first 7 questions become more physically active.

KOOS

Physical functioning of patients was assessed with this questionnaire. It has 5 subgroups: pain, symptoms, functional status in activities of daily living, sports and leisure activities, and knee-related quality of life. It consists of 42 questions in total [34].

Pain severity

It was evaluated with the Numeric Rating Scale (NRS). The NRS is a semi-quantitative method for subjective measurement of a sensitivity level (e.g., pain). This scale consists of a line [35]. Moving away from the left edge on this line indicates an increase in sensory intensity (e.g., 0: No pain (left edge), 10: Unbearable pain (right edge)) [36].

Physical activity level

It was assessed by the International Physical Activity Questionnaire Short Form (IPAQ-SF). It is a form consisting of 9 questions used to measure the physical activity level of the participants. The questions are about the time the participants have consumed in physical activity they have done in the last week. The IPAQ allows the calculation of metabolic equivalent (MET) by measuring frequency, duration, and physical activity intensity level over the past 7 days across all contexts and presents the amount of physical activity per week. It is calculated as weekly working hours (MET-hours/week) [37].

HADS

This scale is a self-report scale and consists of 14 items, 7 of which investigate depression and 7 anxiety symptoms. The purpose of the scale is not to make a diagnosis. It is to determine the risk group by screening for anxiety and depression in a short time in patients with physical illness. In addition, the scale can be used to evaluate the change in the emotional status of patients [38].

QUIPA

It is a patient-based outcome measurement method in which the quality of the physiotherapy treatment received by patients for hip and/or KOA is evaluated. It consists of 17 questions [39].

TKS

It is a 17-item scale developed to assess fear of movement/re-injury. The scale includes parameters of injury/re-injury and fear-avoidance in work-related activities [40].

EARS

It is a 16-item scale developed to evaluate the adherence of individuals to the exercises recommended for individuals with chronic diseases, and the reasons for their compliance or non-compliance. It consists of 3 subscales. Subscale A does not participate in scoring. Subscale B (evaluates self-reported adherence to exercises) consists of 6 questions and subscale C (evaluates the reasons for the compliance or non-compliance with the recommended exercise) consist of 10 questions, and these subscales are scored. [41].

FSS

It is a 9-item scale developed to assess fatigue. The participant is asked to answer the questions considering his fatigue in the last 1 month, including the day of the evaluation [42].

Patient satisfaction with treatment

It was evaluated with a 5-point Likert scale. For this scale, the lowest score indicates “not satisfied at all,” and the highest score indicates “very satisfied” [43].

Thirty-second chair stand test (30 CST), Knee Injury and Osteoarthritis Outcome Score (KOOS), NRS, IPAQ, HAQ, TAMPA Kinesiophobia Scale (TKS), and Fatigue Severity Scale (FSS) were evaluated twice, before and after the treatment. The Exercise Adherence Rating Scale (EARS), Quality Indicators Questionnaire for Physiotherapy Management of Hip and Knee Osteoarthritis (QUIPA tool), and the patient’s level of satisfaction with the treatment will be administered and evaluated after treatment only.

Statistical analysis

The minimum sample size to be included in the study was analyzed using the G-Power (Version 3.1.9.2, University of Dusseldorf, Dusseldorf, Germany) program. According to the results of the sample size analysis performed with 5% type 1 and 90% type 2 errors, the study was planned with a total of 40 patients, 20 of which were in the telerehabilitation group and 20 of which were in the control group. Considering the possible losses, it was decided to include at least 22 patients for both groups. SPSS 25 (IBM Corp. Released 2017. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.) was used to analyze the data. Qualitative data were expressed as percentages, and quantitative data were expressed as mean ± standard deviation. The conformity of the data to the normal distribution was evaluated with the Shapiro–Wilk and Levene tests. Multiple regression analysis was carried out to analyze post-intervention outcome measures as independent variables and the telerehabilitation or control group as dependent variables. Pre-intervention outcome measures were subsumed as covariates. The statistical significance level was accepted as p < 0.05 for all the analyses performed [44].

Results

The participant flowchart of the control and intervention group, including losses to follow-up and exclusions, is demonstrated in Fig. 1. Out of a total of 64 patients interviewed for the study, 50 patients meeting the inclusion criteria were randomized, 25 to the telerehabilitation group and 25 to the control group. One participant in both groups was lost to follow-up and hence also excluded from the analyses. A total of 48 patients were analyzed. The mean age of patients was 55.83 ± 6.93 years, and 43 (89.6%) patients were women. The mean age of patients in the telerehabilitation group was 55.87 ± 7.24 years, and it was 55.79 ± 6.76 years in the control group. There were 21 (87.5%) women in the intervention, and 22 women (91.7%) in the control group. No significant differences were observed between groups with regard to gender and age before treatment. Most of the patients in both groups were primary school graduates and non-working. The mean baseline demographic and clinical characteristics are presented in Table 1. The variables were similar for patients in both groups.

Fig. 1
figure 1

Flowchart of participants

Table 1 Demographic and clinical characteristics of patients

Table 2 indicates the multiple regression analysis findings. The telerehabilitation group demonstrated significant improvements for the outcomes of the number of painkillers used in the last 15 days, 30 CST, knee pain on the NRS, KOOS total, and all the subscales’ scores, Hospital Anxiety and Depression Scale (HADS) total and both subscales scores, TKS score, FSS score, and IPAQ-SF score. The control group indicated significant improvements in the 30 CST, KOOS daily living activities and function subscale, HADS total, and both subscales scores and TKS score.

Table 2 Change in primary and secondary outcomes

Mean change from baseline to 8 weeks indicated that the number of painkillers used in the last 15 days (between-group difference, − 4.62[95%CI, − 6.32 to -2.92]; p ≤ 0.001); 30 CST (between-group difference, 5.25 [95%CI, 4.18 to 6.31]; p ≤ 0.001); knee pain on the NRS (between-group difference, − 3.83 [95%CI, − 5.10 to − 2.56]; p ≤ 0.001); KOOS total (between-group difference, 27.66 [95%CI, 15.44 to 39.88]; p ≤ 0.001), symptoms (between-group difference, 24.75 [95%CI, 12.90 to 36.59]; p ≤ 0.001), pain (between-group difference, 30.95 [95%CI, 18.77 to 43.14]; p ≤ 0.001), functional status-daily living activities (between-group difference, 29.54 [95%CI, 17.07 to 42.01]; p ≤ 0.001), functional status-sports and leisure activities (between-group difference, 30.20 [95%CI, 14.08 to 46.33]; p ≤ 0.001) and knee-related QoL (between-group difference, 23.95 [95%CI, 11.28 to 36.63]; p ≤ 0.001) subscales’ scores; and HADS total (between-group difference, − 5.33 [95%CI, − 8.20 to − 2.46]; p ≤ 0.001), anxiety (between-group difference, − 2.62[95%CI, − 4.37 to 0.87]; p = 0.004), and depression (between-group difference, − 2.70[95%CI, − 4.21 to − 1.19]; p ≤ 0.001) subscales’ scores; TKS score (between-group difference, − 4.79[95%CI, − 8.21 to1.36]; p = 0.007), FSS score (between-group difference, − 1.91[95%CI, − 2.62 to − 1.20]; p ≤ 0.001), and IPAQ-SF score (between-group difference, 394.77[95%CI, 19.05 to 770.48]; p = 0.040) outcomes improved significantly in the telerehabilitation group compared to the control group (Table 2). No serious adverse events were notified in any of the groups.

The parameters evaluated only after the end of treatment are shown in Table 3. After 8 weeks of treatment, it was determined that there was a statistical difference in all subscales and total score of QUIPA in the telerehabilitation group compared to the control group. Moreover, there was a statistical difference in the C subscale and total score of EARS in the telerehabilitation group compared to the control group. However, no statistically significant difference was found between the telerehabilitation and control groups for the B subscale of EARS. When the treatment satisfaction levels of the groups were compared, it was determined that there was a statistically significant difference in the telerehabilitation group compared to the control group.

Table 3 Parameters evaluated after treatment only

Discussion

Until today, unfortunately, the great majority of patients with KOA remains sedentary and receives no support for the augmentation of physical activity. Since a physically active way of life has been linked with decreased pain and increased physical function, accessible and effective physiotherapy programs are required [45]. Therefore, this study was designed to determine the effectiveness of telerehabilitation and the quality of physiotherapy for patients with KOA. The aim of this study was to examine the effects of telerehabilitation on physical performance, pain, functional status, emotional status, kinesiophobia, fatigue, and physical activity level in patients with KOA and to evaluate the exercise compliance, satisfaction with the treatment, and the quality of the physiotherapy they received. The results of this study demonstrated improvements in terms of the mentioned parameters for the telerehabilitation group.

It has been reported in the literature that the incidence of KOA is higher in women than in men [46]. In our study, female patients were in the majority in both the telerehabilitation and control groups. In terms of gender distribution, our findings are compatible with studies in the literature [27, 47, 48]. KOA, one of the five leading causes of disability in adults over 50, is a significant threat to patients’ QoL and independence [49]. In our study, the mean age of the patients in the telerehabilitation group and the control group was over 50 years, too. In similar studies in the literature, the mean age of the patients was over 50 years [50,51,52]. In terms of age distribution, our findings are compatible with studies in the literature. Obesity and being overweight are defined as serious risk factors for KOA. Obesity has been shown to cause excessive mechanical stress on the knee joint, which can cause changes in the structure and mechanical properties of the articular cartilage as a result of this stress, resulting in cartilage erosion [53]. Clinically, those with BMI < 18 kg/m2 are accepted as underweight, those with 18–24.9 kg/m2 are accepted as normal weight, those with 25–29.9 kg/m2 are accepted as overweight, and those with 30–39.9 kg/m2 are accepted as obese, and those with > 40 kg/m2 are accepted as morbidly obese [54]. Regarding BMI, patients in both groups can be accepted as obese. In similar studies in the literature, it was determined that the BMI of the patients was over 30, that is, the patients were obese [51, 55]. The mean BMI findings of our study are consistent with the studies in the literature and support the view regarding the effect of obesity on KOA.

Pain is one of the most common symptoms in patients with KOA [56, 57]. The NRS was used to evaluate the severity of pain in our study. Before treatment, pain intensity was similar for both groups. Although pain intensity decreased in both groups after treatment, this decrease was not statistically significant in the control group. When the amount of decrease in the pain intensity after treatment was compared between the groups, it was determined that the amount of decrease in the pain intensity of the telerehabilitation group was statistically significantly higher than the control group. It is known that regular and correct exercise is effective in reducing pain in patients with KOA [14, 58, 59]. In this study, the patients in the telerehabilitation group did their exercises regularly and correctly through simultaneous video conference accompanied by a physiotherapist, the patients were shown the correct application of each exercise they did wrong. On the other side, only an exercise brochure was given to the control group. During the treatment period, the patients in the control group were not reminded to do the exercises. In addition, it is not known whether the exercises recommended to them are performed correctly by the patients with the appropriate number of repetitions and duration. The authors deduced the reason why the decrease in the pain intensity of the patients in the telerehabilitation group was higher than the patients in the control group is that the patients in the telerehabilitation group did their exercises more regularly and correctly. Considering similar studies in the literature, it has been reported that the severity of pain decreases with exercises performed through telerehabilitation [27, 48, 50, 52, 55, 60, 61]. In our study, the finding of a reduction in pain intensity with telerehabilitation is similar to the studies in the literature.

As mentioned above, pain is one of the most common findings in patients with KOA. The number of painkillers used by the two groups in the last 15 days before the treatment was similar. Although it was decreased for both groups, the statistical difference was found only in the telerehabilitation group. Comparing the groups for this parameter, the amount of decrease in the number of painkillers used in the last 15 days of the telerehabilitation group was statistically significantly higher than the control group. When similar studies in the literature were examined, it was reported that the number of painkillers used together with telerehabilitation decreased [28, 48]. Our finding regarding the number of painkillers used by the patients in our study was found to be compatible with other studies. Since the severity of pain decreased more in the telerehabilitation group, the decrease in the number of painkillers used by the patients in this group is an expected finding.

Physical function is affected due to the symptoms that occur in patients with KOA. In our study, physical function was evaluated with the 30 CST. Mean scores of this test were similar for both groups before treatment. After treatment, the mean score increased statistically significantly for both groups. However, the increase in the control group did not reach clinical significance. When the amount of increase in the 30 CST score after the treatment was compared between the groups, it was determined that the amount of increase in the score of the telerehabilitation group was statistically significantly higher than the control group. It is known that regular and correct exercises are effective in reducing symptoms in patients with KOA [62]. In addition, progressive strengthening exercises increase muscle strength [63]. The 30 CST is a physical performance test that also evaluates lower extremity muscle strength [64]. Therefore, an increase in the mean score for this test in patients in both groups in our study is an expected result. In this study, the patients in the telerehabilitation group did their exercises regularly and correctly through simultaneous video conference accompanied by a physiotherapist, the patients were shown the correct application of each exercise they did wrong, and the patients were warned by keeping a certain time for each exercise by a stopwatch. On the other hand, only a brochure was given to the control group. During the treatment period, the patients in the control group were not reminded to do the exercises. In addition, it is not known whether the exercises given to them are performed correctly by the patients with the appropriate number of repetitions and duration. Therefore, these results might be emerged due to the fact that the patients in the telerehabilitation group did their exercises more regularly and correctly. In similar studies in the literature, the result of the change in physical function through telerehabilitation differs. The finding related to physical function in our study is similar to the findings in the study of Gohir et al. and Nero et al. [48, 55] but differs from the finding in the study of Allen et al. [65]. Allen et al. [65] reported that the reason for this finding was due to the lower motivation of the participants in their own study compared to the participants in other studies.

The symptoms developing in patients with KOA affect the functional status of the patients. In our study, functional status was evaluated with KOOS. Before treatment, the total score of the questionnaire and scores for all sub-parameters were similar for both groups. When compared with before treatment, there was a statistically significant difference for both the total score and all sub-parameters of the questionnaire for the telerehabilitation group after the treatment, while a statistically significant difference was found only in the functions in daily living activities sub-parameter in the control group. When the functional status was compared between the post-treatment groups, it was found that the telerehabilitation group had statistically significantly better scores than the control group. It is an expected result that the functional status of the patients in the telerehabilitation group improved as a result of a significant decrease in the severity of pain and an increase in their physical functions. In addition, as mentioned before, the authors think this is due to the fact that the patients in the telerehabilitation group do their exercises more regularly and correctly. In similar studies in the literature, the evaluation of functional status and the effect of telerehabilitation on functional status vary. Functional status was evaluated with KOOS in some studies and with WOMAC in other studies. KOOS includes all of the questions of WOMAC and addresses functional status more comprehensively than WOMAC. When the studies in the literature were examined, the findings obtained for the functional status in our study were similar to the results of the study conducted by Brooks et al. [28], Allen et al. [65], Gohir et al. [55], and Aily et al. [61].

In chronic diseases, as a result of the presence of symptoms such as pain and the limitation of the physical functions of the patients and their activities in daily living activities, emotional status changes can be seen in the patients. In our study, emotional status was evaluated with the HADS. Before treatment, anxiety and depression subparameters and total scores of the questionnaire were similar for both groups. It was determined that there was a statistically significant difference for both the sub-parameters and the total score of the questionnaire for both groups after the treatment when compared with the pre-treatment. In the present study, when the emotional status was compared between the post-treatment groups, it was found that the emotional status was statistically significantly better in the telerehabilitation group compared to the control group. It is an expected result that the emotional status of the patients in the telerehabilitation group improved as a result of the decrease in pain intensity and improvement in physical function and functional status. Additionally, the first evaluation of all patients participating in the study was made during the pandemic process. However, for some patients, the evaluations were made after the end of the treatment which coincides with the end of the restrictions. Recalling the psychological effects of the pandemic on patients, it is thought that the end of the restrictions has also positively affected the emotional status of the patients in the control group. In the study of Bossen et al. [27], emotional status was evaluated with the HADS. As a result of the evaluation made at the 3rd month after the treatment, no statistically significant difference was found between the treatment and control groups in terms of emotional status. As a result of the evaluation made at the 12th month, a statistically significant difference was found in the anxiety level of the treatment group compared to the control group. When similar studies in the literature were scanned, it was determined that emotional status was evaluated only in the study by Bossen et al. [27]. The result of our study is not exactly similar to the results of the study performed by Bossen et al. [27]. The authors think this is because of the fact that there was a pandemic during the process of this study, and the emotional status of the patients was affected due to the restrictions imposed by the government.

Kinesiophobia has been investigated in various patient populations to date and has been found to be associated with increased pain, psychosocial problems, and physical disability [66]. Kinesiophobia is also a condition encountered in patients with KOA. In our study, kinesiophobia was evaluated with the TKS. Before treatment, kinesiophobia scores were similar for both groups. According to the TKS, those who score 13–22 “kinesiophobia is not at the clinical level (subclinical),” those who score 23–32 “mild,” those who score 33–42 “moderate,” and those who score 43–52 “severe” [67]. According to this classification, the patients in both the control group and telerehabilitation group in our study initially had severe kinesiophobia. It was determined that there was a statistically significant difference in terms of kinesiophobia score for both groups after treatment when compared with before treatment. When kinesiophobia was compared between the post-treatment groups, it was found that kinesiophobia was statistically significantly better in the telerehabilitation group than in the control group. It is an expected result that kinesiophobia decreases more as a result of the decrease in pain intensity of the patients and the improvement in their physical function, functional status, and emotional status in the telerehabilitation group compared to the patients in the control group. There is no study in the literature evaluating the effect of telerehabilitation on kinesiophobia in patients with KOA. This study makes a contribution to the literature in terms of evaluating the effect of telerehabilitation on kinesiophobia in patients with KOA.

Almost half of the individuals with OA experience fatigue and are more likely to suffer from fatigue compared to healthy individuals. In studies in the literature, it has been reported that many parameters such as aging, increased pain, psychosocial problems, decreased physical activity, and muscle strength may be related to fatigue in patients with OA. In our study, fatigue was evaluated using the FSS. Fatigue scores were similar for both groups before treatment. There was a statistically significant difference in the severity of fatigue in the telerehabilitation group when compared with the pre-treatment after treatment, but not in the control group. When the severity of fatigue was compared between the post-treatment groups, it was found that the fatigue was statistically significantly better in the telerehabilitation group compared to the control group. The authors think this is due to the fact that the intensity of pain decreased more, physical functions and functional status increased more, and emotional status improved more in the individuals in the telerehabilitation group compared to the control group. In similar studies, fatigue was assessed using the NRS or VAS [27, 52]. When the results of these studies are examined, the findings of fatigue severity in our study are similar to the results of these studies.

Physical activity level might be affected by disease-related symptoms, kinesiophobia, and fatigue in patients with KOA. In our study, physical activity level was evaluated with the IPAQ-SF. Physical activity scores were similar for both groups before treatment. There was a statistically significant difference in the level of physical activity in the telerehabilitation group when compared to the pre-treatment level after the treatment, but not in the control group. When the physical activity level was compared between the post-treatment groups, it was found that the level of physical activity in the telerehabilitation group was statistically significantly better than the control group. The authors deduce that this is due to the fact that the severity of pain, kinesiophobia, and fatigue of the individuals decreased more and their physical functions and functional and emotional status improved more in the telerehabilitation group compared to the individuals in the control group. In similar studies, physical activity level was evaluated with different methods such as accelerometer [47], SQUASH Questionnaire [60], and Physical Activity Score [27, 65]. When the results of these studies are examined, our results are similar to the long-term (12 months) results of the studies conducted by Bossen [27] and Allen et al. [65]. However, in another study by Bossen et al. [60] in which patients were evaluated at the 6th and 12th weeks, and in the study of Kloek et al. [47], in which the patients were followed up for long term (12 months), no statistically significant difference was found in the physical activity result compared to the pre-treatment. The authors think the difference between the physical activity results in this study and the mentioned studies in the literature is due to the fact that the patients were educated before the treatment and the importance of physical activity was mentioned during the patient education. In addition, while the telerehabilitation group was treated simultaneously with video conference, the physiotherapist answered the questions of the patients on this subject and may have been effective in the emergence of these results.

The quality of the physiotherapy received by the patients was evaluated with the QUIPA tool after the treatment. In the present study, it was determined that there was a statistically significant difference between the two groups for all sub-parameters and the total score of the QUIPA. According to these results, it was determined that the telerehabilitation group found the quality of the physiotherapy they received statistically significantly higher than the control group. Before the treatment, both groups were given the patient education which explains KOA, its symptoms, the progress of the disease, the effects of the disease on the patients, the units that patients should apply when they are affected, suggestions to the patients in order not to increase the severity of the disease, and the tools they could use to increase the functions in daily life. All the explained information in patient education met the answers to all the questions of the QUIPA tool. The patients in the telerehabilitation group were able to ask questions regarding the information they learned in the patient education to the physiotherapist during the simultaneous video conference. Thus, their knowledge was current and more advanced. This can be the explanation of why the QUIPA results of the patients in the telerehabilitation group were higher than the QUIPA results of the patients in the control group in the post-treatment evaluation. Umapathy et al. [51] evaluated the change in the appropriateness of care received by the participants in their study using the Osteoarthritis Quality Indicator Questionnaire [68]. According to this questionnaire, those who received telerehabilitation from a website for 12 months reported significant improvements in self-management and weight reduction compared to those who did not receive it. The questionnaire used in the study of Umapathy et al. [51] does not only evaluate the treatment quality in terms of physiotherapy but also has questions about pharmacological treatment modalities [68]. In the literature, there is no study evaluating only the quality of physiotherapy with telerehabilitation in patients with KOA. This study is the first to evaluate the quality of physiotherapy received with telerehabilitation in patients with KOA and makes a contribution to the literature in this respect.

Patients’ compliance with exercise was evaluated with the EARS after treatment. In this study, it was determined that there was a statistically significant difference between the two groups for the subscale C and the total score of the questionnaire, but no significant difference was found between the two groups for the subscale B. Subscale B reports compliance with exercise by the patient. Since the patients in both the treatment and control groups stated that they did their exercises, it is an expected finding that there is no difference when the two groups are compared in terms of part B. Considering the total score, it was found that the telerehabilitation group’s adherence to exercise was statistically significantly higher than the control group. It is not a surprising result that the exercise compliance of the patients followed by the physiotherapist is high. In similar studies in the literature, exercise adherence was evaluated with NRS [69] besides EARS [61]. The findings of both of these studies regarding exercise adherence were similar to the findings of our study in terms of this parameter.

In the present study, the satisfaction levels of the patients with the treatment were evaluated by the answers given by the patients to the 5-point Likert Scale to the question “What is your satisfaction level with the treatment?” While 100% of the patients in the telerehabilitation group stated that they were very satisfied or satisfied with the treatment, 58.3% of the patients in the control group stated that they were very satisfied or satisfied. As a result of this study, it was determined that the level of satisfaction with the treatment of the telerehabilitation group was statistically significantly higher than the control group. In similar studies in the literature, the level of satisfaction with the treatment of patients was questioned by a questionnaire [28] or using NRS [69]. The results of this study regarding patients’ level of satisfaction with the treatment was similar to the results of the study of Brooks et al. [28]; however, it was not compatible with the study of Bennell et al. [69]. For this parameter, the authors think the reason for the similarity with the study by Brooks et al. [28] is that the treatment duration for both studies was 8 weeks. However, the treatment duration was 3 weeks, namely, shorter, in the study of Bennell et al. [69].

This is the first study to evaluate the efficacy of physiotherapy and rehabilitation through simultaneous video conference in the presence of a physiotherapist. Moreover, this is the first study to evaluate the change in the level of kinesiophobia due to KOA after the telerehabilitation intervention and the quality of the physiotherapy received by the patients through telerehabilitation. The authors consider the lack of double blind study design to be a limitation of this study.

All in all, as a result of this study it can be concluded that telerehabilitation is superior to self-management. No harm was reported in individuals in either group. Findings from this study indicate that telerehabilitation is a quality practice with the potential to reduce symptoms in patients. For this reason, the authors believe that the findings of this study will not only contribute to the literature but also shed light on people working in this field. Evaluation of the effect of simultaneous telerehabilitation performed with a physiotherapist in terms of cost and effectiveness on the health system is recommended in future studies.