Skip to main content

Advertisement

SpringerLink
Log in

Intussusception merged with systemic lupus erythematosus: one case report and retrospective analysis

  • Case Based Review
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Abstract

Intussusception is characterized by one segment of the gastrointestinal tract telescoping into the lumen of the adjacent segment; it is rarely reported in systemic lupus erythematosus (SLE), and the condition can be threatening. Only four cases of intussusception with SLE have been reported in literature. Here, we describe a new case of a patient with ileocecal intussusception merged with SLE, who was diagnosed using abdominal computed tomography and successfully treated with high-dose intravenous immunoglobulin (IVIG) and pulse methylprednisolone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Azar T, Berger DL (1997) Adult intussusception. Ann Surg 226(2):134–138

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Cervera R, Espinosa G, Cordero A, Oltra MR, Unzurrunzaga A, Rossinol T et al (2007) Intestinal involvement secondary to the antiphospholipid syndrome (APS): clinical and immunologic characteristics of 97 patients: comparison of classic and catastrophic APS. Semin Arthritis Rheum 36(5):287–296

    Article  CAS  PubMed  Google Scholar 

  3. Chang DK, Yoo DH, Kim TH, Kim IS, Jun KY, Park MH et al (1999) Burkitt’s lymphoma presenting as ileocaecal intussusception in systemic lupus erythematosus. Clin Rheumatol 18(3):253–256

    Article  CAS  PubMed  Google Scholar 

  4. Chng HH, Tan BE, Teh CL, Lian TY (2010) Major gastrointestinal manifestations in lupus patients in Asia: lupus enteritis, intestinal pseudo-obstruction, and protein-losing gastroenteropathy. Lupus 19(12):1404–1413

    Article  CAS  PubMed  Google Scholar 

  5. Del Papa N, Guidali L, Sala A, Buccellati C, Khamashta MA, Ichikawa K et al (1997) Endothelial cells as target for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I antibodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation. Arthritis Rheum 40(3):551–561

    Article  PubMed  Google Scholar 

  6. Erkan N, Haciyanli M, Yildirim M, Sayhan H, Vardar E, Polat AF (2005) Intussusception in adults: an unusual and challenging condition for surgeons. Int J Color Dis 20(5):452–456

    Article  Google Scholar 

  7. Haas EM, Etter EL, Ellis S, Taylor TV (2003) Adult intussusception. Am J Surg 186(1):75–76

    Article  PubMed  Google Scholar 

  8. Helliwell TR, Flook D, Whitworth J, Day DW (1985) Arteritis and venulitis in systemic lupus erythematosus resulting in massive lower intestinal haemorrhage. Histopathology 9(10):1103–1113

    Article  CAS  PubMed  Google Scholar 

  9. Hermann G (1967) Intussusception secondary to mesenteric arteries: complication of systemic lupus erythematosus in a 5-year-old child. JAMA 200(1):74–75

    Article  CAS  PubMed  Google Scholar 

  10. Hoffman BI, Katz WA (1980) The gastrointestinal manifestations of systemic lupus erythematosus: a review of the literature. Semin Arthritis Rheum 9(4):237–247

    Article  CAS  PubMed  Google Scholar 

  11. Kwok SK, Seo SH, JH J, Park KS, Yoon CH, Kim WU et al (2007) Lupus enteritis: clinical characteristics, risk factor for relapse and association with anti-endothelial cell antibody. Lupus 16(10):803–809

    Article  CAS  PubMed  Google Scholar 

  12. Lee CK, Ahn MS, Lee EY, Shin JH, Cho YS, Ha HK et al (2002) Acute abdominal pain in systemic lupus erythematosus: focus on lupus enteritis (gastrointestinal vasculitis). Ann Rheum Dis 61(6):547–550

    Article  PubMed  PubMed Central  Google Scholar 

  13. Lian TY, Edwards CJ, Chan SP, Chng HH (2003) Reversible acute gastrointestinal syndrome associated with active systemic lupus erythematosus in patients admitted to hospital. Lupus 12(8):612–616

    Article  CAS  PubMed  Google Scholar 

  14. Lin YJ, Chen PC, Chen HA (2013) Mesenteric vasculitis causing ileocecal intussusception as the initial presentation of systemic lupus erythematosus: a case report. Clin Rheumatol 32(Suppl 1):S37–S40

    Article  PubMed  Google Scholar 

  15. Marinis A, Yiallourou A, Samanides L, Dafnios N, Anastasopoulos G, Vassiliou I et al (2009) Intussusception of the bowel in adults: a review. World J Gastroenterol 15(4):407–411

    Article  PubMed  PubMed Central  Google Scholar 

  16. Marsicovetere P, Ivatury SJ, White B, Holubar SD (2017) Intestinal intussusception: etiology, diagnosis, and treatment. Clin Colon Rectal Surg 30(1):30–39

    Article  PubMed  Google Scholar 

  17. Simantov R, LaSala JM, Lo SK, Gharavi AE, Sammaritano LR, Salmon JE et al (1995) Activation of cultured vascular endothelial cells by antiphospholipid antibodies. J Clin Invest 96(5):2211–2219

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Tan KY, Tan SM, Tan AG, Chen CY, Chng HC, Hoe MN (2003) Adult intussusception: experience in Singapore. ANZ J Surg 73(12):1044–1047

    Article  PubMed  Google Scholar 

  19. Tian XP, Zhang X (2010) Gastrointestinal involvement in systemic lupus erythematosus: insight into pathogenesis, diagnosis and treatment. World J Gastroenterol 16(24):2971–2977

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Wei CC, Chen JH, Cheng HH (1996) Systemic lupus erythematosus with intussusception: a case report. Zhonghua Yi Xue Za Zhi 58(1):58–61

    CAS  PubMed  Google Scholar 

Download references

Author information

Author notes

  1. Jun Fei Zhou and Sheng Yun Liu contributed equally to the work.

Authors and Affiliations

  1. Department of Rheumatology and Immunology, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gong-Ti South Road, Chaoyang District, Beijing, 100020, People’s Republic of China

    Jun Fei Zhou & Yi Zheng

  2. Department of Rheumatology and Immunology, Zhengzhou University First Affiliated Hospital, Zhengzhou, 450000, China

    Sheng Yun Liu

Authors
  1. Jun Fei Zhou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sheng Yun Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yi Zheng
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Authors Jun Fei Zhou and Sheng Yun LIU jointly completed the writing, and author Yi Zheng provided valuable guidance and made comprehensive modification.

Corresponding author

Correspondence to Yi Zheng.

Ethics declarations

This case study was approved by the ethics committee of Zhengzhou University First Affiliated Hospital, and the participant provided informed consent.

Disclosures

None.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhou, J.F., Liu, S.Y. & Zheng, Y. Intussusception merged with systemic lupus erythematosus: one case report and retrospective analysis. Clin Rheumatol 37, 285–288 (2018). https://doi.org/10.1007/s10067-017-3879-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10067-017-3879-z

Keywords

Search

Navigation