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Titanium-coated mesh versus standard polypropylene mesh in laparoscopic inguinal hernia repair: a prospective, randomized, controlled clinical trial

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Abstract

Objective

We aimed to compare the clinical outcome of titanium-coated mesh and polypropylene mesh in laparoscopic inguinal hernia repair.

Methods

A total of 102 patients who received laparoscopic inguinal hernia repair in January–June 2016 in Beijing Chao-Yang Hospital were enrolled in this study. Patients were randomly divided into two groups, receiving either titanium-coated mesh (n = 50) or standard polypropylene mesh (n = 52). Multiple clinical parameters were collected and analyzed, including clinical manifestations, operative time, intraoperative blood loss, hospital stay, hospital cost, recovery time, and postoperative complications.

Results

All procedures were completed. A statistical difference between two groups was not identified in regards to operative time, intraoperative blood loss, hospital stay, and recovery time (P > 0.05). Three cases with seroma and 15 with foreign body sensation were reported in the titanium-coated mesh group; 9 cases with seroma and 17 with foreign body sensation were reported in the standard polypropylene mesh group. There was no significant difference in the incidence of seroma and/or foreign body sensation. A lower hospital cost but longer recovery period was documented in the standard polypropylene mesh group (P < 0.05). No recurrence, infection or chronic pain was observed during 1-year follow-up in both groups.

Conclusion

Titanium-coated mesh possesses comparable clinical qualities as the standard polypropylene mesh but with a shorter recovery period. Therefore, this mesh is promising for clinical practice though the cost is higher than the standard polypropylene mesh.

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Correspondence to J. Chen.

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Conflict of interest

The authors declare that there is no conflict of interest involved.

Ethical approval

This study was approved by the Ethical Committee of the Beijing Chao-Yang hospital.

Human and animal rights

All procedures were approved by the Institutional Review Board of Beijing Chao-Yang Hospital.

Informed consent

Written informed consents were obtained from all the participants before the trial.

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Yang, S., Shen, YM., Wang, MG. et al. Titanium-coated mesh versus standard polypropylene mesh in laparoscopic inguinal hernia repair: a prospective, randomized, controlled clinical trial. Hernia 23, 255–259 (2019). https://doi.org/10.1007/s10029-018-1823-z

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  • DOI: https://doi.org/10.1007/s10029-018-1823-z

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