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Prevalence of signs and symptoms related to temporomandibular disorders and orofacial pain in patients indicated for orthognathic surgery: a meta-analysis

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Abstract

Objective

To evaluate the prevalence of signs and symptoms related to temporomandibular disorders (TMD) and orofacial pain in patients with indication for orthognathic surgery.

Methods

The search was carried out in seven electronic databases and gray literature. Studies that evaluated the frequency of signs and symptoms related to TMD and orofacial pain were included. The risk of bias was assessed using the Joanna Briggs Critical Appraisal tool. A meta-analysis of proportions with a random effect model was performed and the GRADE tool judged the certainty of evidence.

Results

After searching the databases, 1859 references were retrieved, 18 of which were selected for synthesis. The prevalence of individuals with at least one TMD symptom was 51% [CI95% = 44–58%], and 44% of the subjects had temporomandibular joint click/crepitus [CI95% = 37–52%]. Additionally, 28% exhibited symptoms related to muscle disorders [CI95% = 22–35%], 34% had disc displacement with or without reduction [CI95% = 25–44%], and 24% had inflammatory joint disorders [CI95% = 13–36%]. The prevalence of headache was 26% [CI95% = 8–51%]. The certainty of evidence was considered very low.

Conclusion

Approximately 1 in 2 patients with dentofacial deformity presents some sign and symptom related to TMD. Myofascial pain and headache may be present in approximately a quarter of patients with dentofacial deformity.

Clinical relevance

A multidisciplinary treatment is necessary for these patients, involving a professional with expertise in the management of TMD.

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Data availability

The datasets used and/or analyses during the current study are available from the corresponding author on reasonable request.

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Authors and Affiliations

  1. Undergraduate Program in Dentistry, Tuiuti University of Paraná, Curitiba, Paraná, Brazil

    Maysa Raksa Garcia & Bianca Lopes Cavalcante de Leão

  2. Postgraduate Program in Communication Disorders, Tuiuti University of Paraná, Street Sydnei Antonio Rangel Santos, 238 - Santo Inácio, Curitiba, PR, Brazil

    Rayane Délcia da Silva, Flavio Magno Gonçalves, Rosane Sampaio Santos, Angela Graciela Deliga Schroder, Bianca Simone Zeigelboim & Cristiano Miranda de Araujo

  3. Center for Advanced Studies in Systematic Review and Meta-Analysis - NARSM, Curitiba, Paraná, Brazil

    Aline Xavier Ferraz & Weslania Viviane Nascimento

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Contributions

M.R.G., R.D.S., A.X.F., carried out the article selection process, risk of bias analysis, and critical reading of the writing. F.M.G and W.V.N, carried out the construction of figures and tables, and critical reading of the writing. R.S.S., B.L.C.L., A.G.D.S., B.S.Z. performed the writing of the manuscript. C.M.A. coordinated the research, carried out the statistical analyzes and critical reading of the writing.

Corresponding author

Correspondence to Cristiano Miranda de Araujo.

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Garcia, M.R., da Silva, R.D., Ferraz, A.X. et al. Prevalence of signs and symptoms related to temporomandibular disorders and orofacial pain in patients indicated for orthognathic surgery: a meta-analysis. Clin Oral Invest 27, 3307–3319 (2023). https://doi.org/10.1007/s00784-023-05110-2

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