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What is the image appearance of juvenile idiopathic arthritis in MRI, CT, and CBCT of TMJ? A systematic review

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Abstract

Objective

We performed a systematic review to investigate the appearance of imaging signs on magnetic resonance imaging (MRI), cone-beam computed tomography (CBCT), and conventional computed tomography (CT) scans of the temporomandibular joints (TMJs) of patients with juvenile idiopathic arthritis (JIA).

Materials and methods

We performed electronic searches of the PubMed, Embase, Web of Science, Scopus, Lilacs, and the Cochrane Library databases to identify studies investigating JIA and its related imaging findings. Inclusion criteria were as follows: original article studies based on humans and systematic reviews, studies enrolling patients under 18 years of age with a diagnostic of JIA, the use of International League of Associations for Rheumatology (ILAR) criteria and one type of medical imaging (MRI, CBCT, or CT), and papers published in the English language.

Results

A total of six studies met the inclusion criteria, four involving MRI and two involving CBCT. Additionally, all six studies analyzed the imaging findings of pathological TMJ affected by JIA. The results showed that synovial membrane enhancement, condylar erosions, and condylar flattening were the most prevalent imaging findings in JIA.

Conclusion

MRI examinations are more specific for detecting anomalies in the TMJ than CBCT and CT. Additionally, these results must be correlated with clinical signs to verify the correct diagnosis.

Clinical relevance

This study identified the most prevalent imaging signs of JIA to provide an early and correct diagnosis of the disease.

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Authors and Affiliations

  1. Department of Dentistry, State University of Maringá, R Mandacaru 1550, Maringá, Paraná, Brazil

    Giovana Felipe Hara, Rodrigo Lorenzi Poluha, Lilian Cristina Vessoni Iwaki & Liogi Iwaki Filho

  2. Division of Oral Radiology, Department of Oral Diagnosis, Piracicaba Dental School, UNICAMP, University of Campinas, Av. Limeira, Piracicaba, São Paulo, 90113414-903, Brazil

    Gustavo Nascimento de Souza-Pinto, Danieli Moura Brasil & Francisco Haiter Neto

Authors
  1. Giovana Felipe Hara
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  2. Gustavo Nascimento de Souza-Pinto
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  3. Danieli Moura Brasil
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  4. Rodrigo Lorenzi Poluha
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  5. Lilian Cristina Vessoni Iwaki
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  7. Francisco Haiter Neto
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Contributions

All authors contributed to the study’s conception and design. Francisco Haiter Neto was responsible for conceptualization and final revision. Giovana Felipe Hara was responsible for material preparation, data collection, analysis, the writing of the first draft, and translation. Gustavo Nascimento de Souza Pinto was responsible for material preparation, the writing of the first draft, and translation. Danieli Moura Brasil, Rodrigo Lorenzi Poluha, Lilian Cristina Vessoni Iwaki, and Liogi Iwaki Filho commented on previous versions of the manuscript and performed the final revision. All authors read and approved the final manuscript.

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Correspondence to Gustavo Nascimento de Souza-Pinto.

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Hara, G.F., de Souza-Pinto, G.N., Brasil, D.M. et al. What is the image appearance of juvenile idiopathic arthritis in MRI, CT, and CBCT of TMJ? A systematic review. Clin Oral Invest 27, 2321–2333 (2023). https://doi.org/10.1007/s00784-022-04828-9

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