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A proposed new bacteriophage subfamily: “Jerseyvirinae”

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Abstract

Based on morphology and comparative nucleotide and protein sequence analysis, a new subfamily of the family Siphoviridae is proposed, named “Jerseyvirinae” and consisting of three genera, “Jerseylikevirus”, “Sp3unalikevirus” and “K1glikevirus”. To date, this subfamily consists of 18 phages for which the genomes have been sequenced. Salmonella phages Jersey, vB_SenS_AG11, vB_SenS-Ent1, vB_SenS-Ent2, vB_SenS-Ent3, FSL SP-101, SETP3, SETP7, SETP13, SE2, SS3e and wksl3 form the proposed genus “Jerseylikevirus”. The proposed genus “K1glikevirus” consists of Escherichia phages K1G, K1H, K1ind1, K1ind2 and K1ind3. The proposed genus “Sp3unalikevirus” contains one member so far. Jersey-like phages appear to be widely distributed, as the above phages were isolated in the UK, Canada, the USA and South Korea between 1970 and the present day. The distinguishing features of this subfamily include a distinct siphovirus morphotype, genomes of 40.7-43.6 kb (49.6-51.4 mol % G+C), a syntenic genome organisation, and a high degree of nucleotide sequence identity and shared proteins. All known members of the proposed subfamily are strictly lytic.

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Acknowledgments

SM acknowledges funding from NSERC of Canada (Discovery Program). SM holds a Tier 1 Canada Research Chair in Bacteriophages. HA and MWG acknowledge funding from Sentinel Bioactive Paper Network.

Conflict of interest

The authors declare that they have no competing interests.

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Authors and Affiliations

  1. Canadian Research Institute for Food Safety, University of Guelph, Guelph, ON, N1G 2W1, Canada

    Hany Anany & Mansel W. Griffiths

  2. Faculty of Science, Microbiology Department, Ain Shams University, Cairo, Egypt

    Hany Anany

  3. Facultad de Ecología y Recursos Naturales, Escuela de Medicina Veterinaria, Universidad Andres Bello, Republica 440, 8370251, Santiago, Chile

    Andrea I. Moreno Switt

  4. National Salmonella, Shigella and Listeria Reference Laboratory, Medical Microbiology Department, University Hospital Galway, Galway, Ireland

    Niall De Lappe

  5. Faculty of Medicine, Department of Microbiology, Immunology, and Infectiology, Université Laval, Quebec, QC, G1X 4C6, Canada

    Hans-Wolfgang Ackermann

  6. Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, N1G 2W1, Canada

    Andrew M. Kropinski

  7. Department of Food Science, Cornell University, Ithaca, NY, 14850, USA

    Martin Wiedmann

  8. Faculty of Health and Applied Sciences, Centre for Research in Biosciences, University of the West of England, Bristol, BS16 1QY, UK

    Darren M. Reynolds & Dann Turner

  9. Faculté des Sciences et de Génie, Département de Biochimie, de Microbiologie et de bio-informatique, Université Laval, Quebec, QC, G1V 0A6, Canada

    Denise Tremblay & Sylvain Moineau

  10. Public Health Agency of Canada, Laboratory for Foodborne Zoonoses, Guelph, ON, N1G 3W4, Canada

    John H. E. Nash

  11. Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada

    John H. E. Nash

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Anany, H., Switt, A.I.M., De Lappe, N. et al. A proposed new bacteriophage subfamily: “Jerseyvirinae”. Arch Virol 160, 1021–1033 (2015). https://doi.org/10.1007/s00705-015-2344-z

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