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CuMoO4/Ti3C2Tx nanocomposite layers perform as an ultrasensitive electrochemical sensor for the detection of antioxidant rutin

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Abstract

The focus of this paper is laid on synthesizing layered compounds of CuMoO4 and Ti3C2Tx using a simple wet chemical etching method and sonochemical method to enable rapid detection of rutin using an electrochemical sensor. Following structural examinations using XRD, surface morphology analysis using SEM, and chemical composition state analysis using XPS, the obtained CuMoO4/Ti3C2Tx nanocomposite electrocatalyst was confirmed and characterized. By employing cyclic voltammetry and differential pulse voltammetry, the electrochemical properties of rutin on a CuMoO4/Ti3C2Tx modified electrode were examined, including its stability and response to variations in pH, loading, sweep rate, and interference. The CuMoO4/Ti3C2Tx modified electrode demonstrates rapid rutin sensing under optimal conditions and offers a linear range of 1 µΜ to 15 µΜ, thereby improving the minimal detection limit (LOD) to 42.9 nM. According to electrochemical analysis, the CuMoO4/Ti3C2Tx electrode also demonstrated cyclic stability and long-lasting anti-interference capabilities. The CuMoO4/Ti3C2Tx nanocomposite demonstrated acceptable recoveries when used to sense RT in apple and grape samples. In comparison to other interfering sample analytes encountered in the current study, the developed sensor demonstrated high selectivity and anti-interference performance. As a result, our research to design of high-performance electrochemical sensors in the biomedical and therapeutic fields.

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Acknowledgements

This study was funded by the Ministry of Science and Technology of Taiwan under grant number 107-2221-E-131-011 and National Science and Technology Council of Taiwan under grant number 111-2811-E-131-003 and 111-2221-E-131-017-MY2 and Ming Chi University of Technology, Taiwan. This work was funded by the Researchers Supporting Project Number (RSP2024R243) King Saud University, Riyadh, Saudi Arabia. Author JR & AS thank RUSA 2.0, DST (FIST), SERB, DAE-BRNS, TANSCHE, and UGC-DAE-CSR, Indore providing financial support and instruments facility.

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Authors and Affiliations

  1. Centre for High-Pressure Research, School of Physics, Bharathidasan University, Tiruchirappalli, Tamil Nadu, 620024, India

    Jagadeesh Ramadoss & Arumugam Sonachalam

  2. Centre for Applied Research, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu, 602105, India

    Mani Govindasamy

  3. International Ph.D. Program in Innovative Technology of Biomedical Engineering and Medical Devices, Ming Chi University of Technology, New Taipei City, 24303, Taiwan

    Mani Govindasamy

  4. Tamil Nadu Open University, Chennai, 600015, India

    Arumugam Sonachalam

  5. Department of Materials Engineering, Ming Chi University of Technology, New Taipei City, 243303, Taiwan

    Chi-Hsien Huang

  6. Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan City, 33305, Taiwan

    Chi-Hsien Huang

  7. College of Engineering, Chang Gung University, Taoyuan City, 33302, Taiwan

    Chi-Hsien Huang

  8. Department of Chemistry, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia

    Asma A. Alothman

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  1. Jagadeesh Ramadoss
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  2. Mani Govindasamy
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Supplementary Material 1: Figure S1. (a) SEM Images of CuMoO4, and (b) Ti3C2Tx electrode materials. Table S1. Equivalent circuit fitted value for modified electrodes. Table S2. Determination of rutin in real juice samples by DPV method.

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Ramadoss, J., Govindasamy, M., Sonachalam, A. et al. CuMoO4/Ti3C2Tx nanocomposite layers perform as an ultrasensitive electrochemical sensor for the detection of antioxidant rutin. Microchim Acta 191, 226 (2024). https://doi.org/10.1007/s00604-024-06267-7

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