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Preparation of molecularly imprinted ratiometric fluorescence sensor for visual detection of tetrabromobisphenol A in water samples

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Abstract

A sensitive molecularly imprinted ratiometric fluorescence sensor was constructed for the first time to visually detect tetrabromobisphenol A (TBBPA). The blue fluorescent carbon quantum dots (CQDs) were coated with SiO2 through the reverse microemulsion method to obtain a stable internal reference signal CQDs@SiO2. The ratiometric fluorescence sensor was finally prepared using red fluorescent CdTe QDs as the response signal in the presence of CQDs@SiO2. When the molecularly imprinted polymers were combined with TBBPA, the fluorescence of CdTe QDs (Ex = 365 nm, Em = 665 nm) was rapidly quenched, while that of CQDs (Ex = 365 nm, Em = 441 nm) remained stable, resulting in a noticeable fluorescence color change. Moreover, the fluorescence intensity ratio (I665/I441)0/(I665/I441) of the sensor showed a linear response to TBBPA in the concentration range 0.1 to 10 μM with a low detection limit of 3.8 nM. The prepared sensor was successfully applied to detect TBBPA in water samples. The recoveries were in the range 98.2–103%, with relative standard deviations lower than 2.5%. Furthermore, a fluorescent test strip for visual monitoring of TBBPA was constructed to streamline the procedure. The excellent results demonstrate that the prepared test strip has a broad prospect for the offline detection of pollutants.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (Program No. 21806097), Scientific Research Program Funded by Shaanxi Provincial Education Department (Program No. 18JK0104), and Research Starting Foundation of Shaanxi University of Science and Technology (Program No. 2016BJ-80).

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Key Laboratory of Auxiliary Chemistry and Technology for Chemical Industry, Ministry of Education, Shaanxi Key Laboratory of Chemical Additives for Industry, Shaanxi University of Science and Technology, Xi’an, Shaanxi, 710021, People’s Republic of China

    Yanming Shao, Peng Wang, Rui Zheng, Zhizhen Zhao, Jun An, Caifeng Hao & Mengyi Kang

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  1. Yanming Shao
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  2. Peng Wang
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  3. Rui Zheng
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  6. Caifeng Hao
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Contributions

Yanming Shao: Conceptualization; Investigation; Methodology; Data curation; Supervision; Writing-original draft; Writing-review & editing. Peng Wang: Investigation; Methodology; Formal analysis; Data curation; Validation; Writing-original draft; Writing-review & editing. Rui Zheng: Methodology; Formal analysis. Zhizhen Zhao: Investigation; Data curation. Jun An: Resources; Validation. Caifeng Hao: Data curation. Mengyi Kang: Validation.

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Correspondence to Yanming Shao.

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Shao, Y., Wang, P., Zheng, R. et al. Preparation of molecularly imprinted ratiometric fluorescence sensor for visual detection of tetrabromobisphenol A in water samples. Microchim Acta 190, 161 (2023). https://doi.org/10.1007/s00604-023-05745-8

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