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Self-enhancement photoelectrochemical strategy for kanamycin determination with amino functionalized MOFs

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Abstract

Based on the self-enhanced photoelectrochemical quality of Cu-MOF-NH2, a photoelectrochemical biosensor for kanamycin detection with a Cu-MOF-NH2 modified electrode was constructed. This biosensor took full advantage of the low electron hole recombination rate due to the ligand-to-metal charge-transfer mechanism of excited electron transfer in Cu-MOF-NH2. The kanamycin aptamer was modified onto Cu-MOF-NH2 by Schiff base reaction. In the presence of kanamycin, the holes on the amino group in Cu-MOF-NH2 oxidize kanamycin, making kanamycin itself as a signal enhancement substance, and achieving the effect of self-enhancement. The dynamic monitoring range for kanamycin is 0.5 to 650 nM, and the detection limit is 0.1 nM. The sensor has been successfully applied to the determination of kanamycin in fish with recoveries of 95.7–105.0% and RSD of 1.5–4.0%. This work provides a broad path for the development of self-enhanced photoelectrochemical sensors.

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References

  1. Han F, Song Z, Nawaz MH, Dai M, Han D, Han L, Fan Y, Xu J, Han D, Niu L (2019) MoS2/ZnO-heterostructures-based label-free, visible-light-excited photoelectrochemical sensor for sensitive and selective determination of synthetic antioxidant propyl gallate. Anal Chem 91(16):10657–10662

    Article  CAS  Google Scholar 

  2. Ge L, Liu Q, Hao N, Kun W (2019) Recent developments of photoelectrochemical biosensors for food analysis. J Mater Chem 7(46):7283–7300

    Article  CAS  Google Scholar 

  3. Zhang L, Luo Z, Su L, Tang D (2019) A surface plasmon resonance enhanced photoelectrochemical immunoassay based on perovskite metal oxide@gold nanoparticle heterostructures. Analyst 144(19):5717–5723

    Article  CAS  Google Scholar 

  4. Najlaoui D, Echabaane M, Ben Khélifa A, Rouis A, Ben Ouada H (2019) Photoelectrochemical impedance spectroscopy sensor for cloxacillin based on tetrabutylammonium octamolybdate. J Solid State Electrochem 23(12):3329–3341

    Article  CAS  Google Scholar 

  5. Jalali M, Moakhar RS, Abdelfattah T, Filine E, Mahshid SS, Mahshid S (2020) Nanopattern-assisted direct growth of peony-like 3D MoS2/Au composite for nonenzymatic photoelectrochemical sensing. ACS Appl Mater Interfaces 12(6):7411–7422

    Article  CAS  Google Scholar 

  6. Zhou Y, Yin H, Ai S (2021) Applications of two-dimensional layered nanomaterials in photoelectrochemical sensors: a comprehensive review. Coord Chem Rev 447:214156

    Article  CAS  Google Scholar 

  7. Madhavi J, Prasad V, Reddy KR, Venkata Reddy C, Raghu AV (2021) Facile synthesis of Ni-doped ZnS-CdS composite and their magnetic and photoluminescence properties. J Environ Chem Eng 9(6):106335

    Article  CAS  Google Scholar 

  8. Jonnalagadda M, Prasad VB, Raghu AV (2021) Synthesis of composite nanopowder through Mn doped ZnS-CdS systems and its structural, optical properties. J Mol Struct 1230:129875

    Article  CAS  Google Scholar 

  9. Jyothi MS, Nayak V, Reddy R, Naveen S, Anjanapura R (2019) Non-metal (oxygen, sulphur, nitrogen, boron and phosphorus)-doped metal oxide hybrid nanostructures as highly efficient photocatalysts for water treatment and hydrogen generation. In book: American Jewish Year Book pp. 83–105

  10. Kumar S, Reddy KR, Reddy CV, Shetti NP, Sadhu V, Shankar MV, Reddy VG, Raghu AV, Aminabhavi TM (2021) Metal nitrides and graphitic carbon nitrides as novel photocatalysts for hydrogen production and environmental remediation. In book: Nanostructured Materials for Environmental Applications pp.485–519

  11. Alvaro M, Carbonell E, Ferrer B, Llabrés i Xamena FX, Garcia H (2007) Semiconductor behavior of a metal-organic framework (MOF). Chem A Eur J 13(18):5106–5112

  12. Tachikawa T, Choi J, Fujitsuka M, Majima T (2008) Photoinduced charge-transfer processes on MOF-5 nanoparticles: elucidating differences between metal-organic frameworks and semiconductor metal oxides. J Phys Chem C 112:14090–14101

    Article  CAS  Google Scholar 

  13. Cao Y, Wang L, Wang C, Hu X, Liu Y, Wang G (2019) Sensitive detection of glyphosate based on a Cu-BTC MOF/g-C3N4 nanosheet photoelectrochemical sensor. Electrochim Acta 317:341–347

    Article  CAS  Google Scholar 

  14. Zhang G-Y, Zhuang Y-H, Shan D, Su G-F, Cosnier S, Zhang X-J (2016) Zirconium-based porphyrinic metal–organic framework (PCN-222): enhanced photoelectrochemical response and its application for label-free phosphoprotein detection. Anal Chem 88(22):11207–11212

    Article  CAS  Google Scholar 

  15. Vidyavathi GT, Kumar BV, Raghu AV, Aravinda T, Hani U, Murthy HCA, Shridhar AH (2022) Punica granatum pericarp extract catalyzed green chemistry approach for synthesizing novel ligand and its metal(II) complexes: molecular docking/DNA interactions. J Mol Struct 1249:131656

    Article  CAS  Google Scholar 

  16. Xu Y, Han T, Li X, Sun L, Zhang Y, Zhang Y (2015) Colorimetric detection of kanamycin based on analyte-protected silver nanoparticles and aptamer-selective sensing mechanism. Anal Chim Acta 891:298–303

    Article  CAS  Google Scholar 

  17. Song K-M, Cho M, Jo H, Min K, Jeon SH, Kim T, Han MS, Ku JK, Ban C (2011) Gold nanoparticle-based colorimetric detection of kanamycin using a DNA aptamer. Anal Biochem 415(2):175–181

    Article  CAS  Google Scholar 

  18. Wan J, Shen Y, Xu L, Xu R, Zhang J, Sun H, Zhang C, Yin C, Wang X (2021) Ferrocene-functionalized Ni(II)-based metal-organic framework as electrochemical sensing interface for ratiometric analysis of Cu2+, Pb2+ and Cd2+. J Electroanal Chem 895:115374

    Article  CAS  Google Scholar 

  19. Song Z, Fan G-C, Li Z, Gao F, Luo X (2018) Universal design of selectivity-enhanced photoelectrochemical enzyme sensor: integrating photoanode with biocathode. Anal Chem 90(18):10681–10687

    Article  CAS  Google Scholar 

  20. Yang L, Zhu G, Wen H, Guan X, Sun X, Feng H, Tian W, Zheng D, Cheng X, Yao Y (2019) Construction of a highly–oriented layered MOF nanoarray from a layered double hydroxide for efficient and durable alkaline water oxidation electrocatalysis. J Mater Chem A 7:8771–8776

    Article  CAS  Google Scholar 

  21. Tang R, Yin R, Zhou S, Ge T, Yuan Z, Zhang L, Yin L (2017) Layered MoS2 coupled MOFs-derived dual-phase TiO2 for enhanced photoelectrochemical performance. J Mater Chem A 5(10):4962–4971

    Article  CAS  Google Scholar 

  22. Usman M, Mendiratta S, Lu K-L (2017) Semiconductor metal–organic frameworks: future low-bandgap materials. Adv Mater 29(6):1605071

    Article  Google Scholar 

  23. Nasalevich M, van der Veen M, Kapteijn F, Gascon J (2014) Metal-organic frameworks as heterogeneous photocatalysts: advantages and challenges. CrystEngComm 16:4919

    Article  CAS  Google Scholar 

  24. Hendon CH, Tiana D, Fontecave M, Sanchez C, D’arras L, Sassoye C, Rozes L, Mellot-Draznieks C, Walsh A (2013) Engineering the optical response of the titanium-MIL-125 metal–organic framework through ligand functionalization. J Am Chem Soc 135(30):10942–10945

    Article  CAS  Google Scholar 

  25. Wang L, Tian G, Chen Y, Xiao Y, Fu H (2016) In situ formation of a ZnO/ZnSe nanonail array as a photoelectrode for enhanced photoelectrochemical water oxidation performance. Nanoscale 8(17):9366–9375

    Article  CAS  Google Scholar 

  26. Wang J, Cherevan AS, Hannecart C, Naghdi S, Nandan SP, Gupta T, Eder D (2021) Ti-based MOFs: new insights on the impact of ligand composition and hole scavengers on stability, charge separation and photocatalytic hydrogen evolution. Appl Catal B Environ 283:119626

    Article  CAS  Google Scholar 

  27. Wang Y, Run Z, Zhang Z, Cao J-L, Ma T (2019) Graphitic carbon nitride: host-guest recognition on 2D graphitic carbon nitride for nanosensing (Adv. Mater. Interfaces 23/2019). Adv Mater Interfaces 6:1970144

    Article  Google Scholar 

  28. Leung K-H, He H-Z, Chan DS-H, Fu W-C, Leung C-H, Ma D-L (2013) An oligonucleotide-based switch-on luminescent probe for the detection of kanamycin in aqueous solution. Sens Actuators, B Chem 177:487–492

    Article  CAS  Google Scholar 

  29. Sharma TK, Ramanathan R, Weerathunge P, Mohammadtaheri M, Daima HK, Shukla R, Bansal V (2014) Aptamer-mediated ‘turn-off/turn-on’ nanozyme activity of gold nanoparticles for kanamycin detection. Chem Commun 50(100):15856–15859

    Article  CAS  Google Scholar 

  30. Wang Y, Ma T, Ma S, Liu Y, Tian Y, Wang R, Jiang Y, Hou D, Wang J (2017) Fluorometric determination of the antibiotic kanamycin by aptamer-induced FRET quenching and recovery between MoS2 nanosheets and carbon dots. Microchim Acta 184(1):203–210

    Article  CAS  Google Scholar 

  31. Tang Y, Gu C, Wang C, Song B, Zhou X, Lou X, He M (2018) Evanescent wave aptasensor for continuous and online aminoglycoside antibiotics detection based on target binding facilitated fluorescence quenching. Biosens Bioelectron 102:646–651

    Article  CAS  Google Scholar 

  32. Yao X, Shen J, Liu Q, Fa H, Yang M, Hou C (2020) A novel electrochemical aptasensor for the sensitive detection of kanamycin based on UiO-66-NH2/MCA/MWCNT@rGONR nanocomposites. Anal Methods 12(41):4967–4976

    Article  CAS  Google Scholar 

  33. Yang H, Wu Q, Su D, Wang Y, Li L, Zhang X (2017) A label-free and turn-on fluorescence strategy for kanamycin detection based on the NMM/G-quadruplex structure. Anal Sci 33(2):133–135

    Article  CAS  Google Scholar 

Download references

Funding

This work was supported by National Natural Science Foundation of China (21575073), the Open Foundation from the Academic Division of Chemistry, Qingdao University of Science and Technology (QUSTHX201907) and Laoshan Scholar Program of Qingdao University of Science and Technology (201802685).

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Authors and Affiliations

  1. Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, People’s Republic of China

    Yang Wang, Daobin Jin, Xiaoqian Zhang, Jikuan Zhao & Xu Hun

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  1. Yang Wang
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  2. Daobin Jin
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  3. Xiaoqian Zhang
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  4. Jikuan Zhao
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Correspondence to Jikuan Zhao or Xu Hun.

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Wang, Y., Jin, D., Zhang, X. et al. Self-enhancement photoelectrochemical strategy for kanamycin determination with amino functionalized MOFs. Microchim Acta 189, 193 (2022). https://doi.org/10.1007/s00604-022-05266-w

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  • DOI: https://doi.org/10.1007/s00604-022-05266-w

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