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Degenerative lumbar scoliosis patients with proximal junctional kyphosis have lower muscularity, fatty degeneration at the lumbar area

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Abstract

Purpose

To assess the lumbar muscle conditions on the incidence of proximal junctional kyphosis (PJK) after long-level correction and instrumentation surgery for degenerative lumbar scoliosis (DLS) patients with a minimum 2-year follow-up.

Methods

Eighty-four DLS patients undergoing long instrumented fusion surgery (≥ 5 vertebrae) were retrospectively studied. According to the occurrence of PJK at the final follow-up, patients were divided into the PJK group and the Non-PJK group. Patient characteristics, surgical variables and radiographic parameters were analyzed statistically. The lumbar muscularity (cross-sectional area of muscle–disc ratio × 100) and fatty degeneration (signal intensity of muscle–subcutaneous fat ratio × 100) were evaluated on magnetic resonance imaging .

Results

The prevalence of PJK was 20.24%. Gender, age at surgery, body mass index, uppermost instrumented vertebrae level, fusions extending to the sacrum, and levels fused were not significantly different between the groups. Lower bone mineral density, smaller functional cross-sectional area (FCSA) of paraspinal extensor muscles (PSE), higher lean muscle–fat index and total muscle–fat index of PSE, greater preoperative thoracolumbar kyphosis (TLK), smaller preoperative sacral slope (SS), larger preoperative sagittal vertical axis were identified in PJK group. Logistic regression analysis showed that osteoporosis, preoperative TLK > 15°, SS > 24°, FCSA of PSE > 138.75, and total muscle–fat index of PSE > 4.08 were independently associated with PJK. The final follow-up VAS score for back pain was higher, and SRS-22 subcategories of pain, function, self-image, and total score were significantly lower in the PJK group.

Conclusion

Osteoporosis, lower lumbar muscularity and higher fatty degeneration, preoperative greater TLK and smaller SS were found to be strongly associated with the presence of PJK in DLS.

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Authors and Affiliations

  1. Department of Orthopedics, Peking University Third Hospital, No 49, North Garden Street, Hai Dian District, Beijing, 100191, China

    Lei Yuan, Yan Zeng, Zhongqiang Chen, Weishi Li, Xinling Zhang & Shuo Mai

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  1. Lei Yuan
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  2. Yan Zeng
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Yuan, L., Zeng, Y., Chen, Z. et al. Degenerative lumbar scoliosis patients with proximal junctional kyphosis have lower muscularity, fatty degeneration at the lumbar area. Eur Spine J 30, 1133–1143 (2021). https://doi.org/10.1007/s00586-020-06394-8

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  • DOI: https://doi.org/10.1007/s00586-020-06394-8

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