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The impact of bone mineral density testing, fracture assessment, and osteoporosis education in men treated by androgen deprivation for prostate cancer: a pilot study

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Abstract

Purpose

Men receiving androgen deprivation therapy for prostate cancer have low knowledge of osteoporosis (OP) and engage in few healthy bone behaviors (HBBs). A multicomponent intervention was piloted in this population. Changes in OP knowledge, self-efficacy, health beliefs, and engagement in HBBs were evaluated.

Methods

A pre-post pilot study was performed in a convenience sample of men recruited from the Princess Margaret Cancer Centre. Men were sent personalized letters explaining their dual x-ray absorptiometry (DXA) results and fracture risk assessment with an OP-related education booklet. Participants completed questionnaires assessing OP knowledge, self-efficacy, health beliefs, and current engagement in HBBs at baseline (T1) and 3 months post-intervention (T2). Paired t tests and McNemar’s test were used to assess changes in outcomes.

Results

A total of 148 men completed the study. There was an increase in OP knowledge (9.7 ± 4.3 to 11.4 ± 3.3, p < 0.0001) and feelings of susceptibility (16.5 ± 4.3 to 17.4 ± 4.7, p = 0.015), but a decrease in total self-efficacy (86.3 ± 22.9 to 81.0 ± 27.6, p = 0.007) from baseline to post-intervention. Men made appropriate changes in their overall daily calcium intake (p ≤ 0.001), and there was uptake of vitamin D supplementation from 44 % (n = 65) to 68 % (n = 99) (p < 0.0001). Men with bone loss (osteopenia or OP) had a greater change in susceptibility (1.9 ± 4.3 vs. −0.22 ± 4.2, p = 0.005) compared to men with normal bone density.

Conclusions

Our results provide preliminary evidence that a multicomponent intervention such as the one described can lead to increased knowledge and feelings of susceptibility regarding OP and can enhance uptake of some HBBs.

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Authors and Affiliations

  1. Undergraduate Medicine Program, University of Toronto CREMS Scholar Program, Toronto, ON, Canada

    Michelle Nadler

  2. University Health Network, Department of Medicine, University of Toronto, Toronto, ON, Canada

    Michelle Nadler & Shabbir Alibhai

  3. Department of Radiation Oncology, Princess Margaret Hospital, Toronto, ON, Canada

    Pamela Catton & Charles Catton

  4. Cancer Survivorship Program, Princess Margaret Cancer Centre, Toronto, ON, Canada

    Jennifer Jones

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  1. Michelle Nadler
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  2. Shabbir Alibhai
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  3. Pamela Catton
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  4. Charles Catton
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  5. Jennifer Jones
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Correspondence to Jennifer Jones.

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Nadler, M., Alibhai, S., Catton, P. et al. The impact of bone mineral density testing, fracture assessment, and osteoporosis education in men treated by androgen deprivation for prostate cancer: a pilot study. Support Care Cancer 22, 2409–2415 (2014). https://doi.org/10.1007/s00520-014-2183-6

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  • DOI: https://doi.org/10.1007/s00520-014-2183-6

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