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Quality of life in children with chronic kidney disease

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Abstract

Background

Progressive chronic kidney disease (CKD), irrespective of the underlying etiology, affects the quality of life (QoL) of children due to the need for regular follow-up visits, a strict medication program and diet intake.

Methods

The Greek version of the KIDSCREEN-52 multidimensional questionnaire was used in children with CKD, renal transplantation (RT) and in a control group (CG) of healthy children.

Results

Fifty-five patients between 8 and 18 years, with CKD (n = 25), RT (n = 16) and with end-stage renal disease (ESRD) on peritoneal dialysis (PD) (n = 14) were included. Each group of studied children was compared with the CG (n = 55), the validation sample (VS) (n = 1200) and the parent proxy scores. Physical well-being of all studied children was significantly lower compared to CG (p = 0.004). In contrast, all studied children between 8 and 11 years showed better social acceptance compared to VS (p = 0.0001). When QoL of children with CKD was compared with parent proxy QoL, conflicting opinions were observed in several dimensions, such as self-perception (p = 0.023), autonomy (p = 0.012), school environment (p = 0.012) and financial resources (p = 0.03).

Conclusions

QoL and mainly the dimension of physical well-being, may be affected dramatically in children with CKD unrelated to disease stage. In early school years children with CKD seem to feel higher social acceptance than the healthy controls, exhibiting better score in this dimension. Optimal care requires attention not only to medical management, but also to an assessment of QoL factors, that may help promote pediatric patient’s health.

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Authors and Affiliations

  1. First Department of Pediatrics, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece

    John Dotis, Antigoni Pavlaki, Nikoleta Printza, Stella Stabouli, Chrysa Gkogka & Fotios Papachristou

  2. Open University of Cyprus, Latsia, Nicosia, Cyprus

    John Dotis & Nikolaos Kontodimopoulos

  3. Department of Pediatrics, General Hospital of Xanthi, Xanthi, Greece

    Stamatia Antoniou

Authors
  1. John Dotis
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  2. Antigoni Pavlaki
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  3. Nikoleta Printza
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  4. Stella Stabouli
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  5. Stamatia Antoniou
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  7. Nikolaos Kontodimopoulos
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  8. Fotios Papachristou
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Correspondence to John Dotis.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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The authors declare that they have no conflict of interest.

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Dotis, J., Pavlaki, A., Printza, N. et al. Quality of life in children with chronic kidney disease. Pediatr Nephrol 31, 2309–2316 (2016). https://doi.org/10.1007/s00467-016-3457-7

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  • DOI: https://doi.org/10.1007/s00467-016-3457-7

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