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Analysis of 24 Y-STR haplotype data in a Chinese Han population from Guangdong Province

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Abstract

In this study, we investigated the genetic polymorphisms of 24 Y-chromosomal short tandem repeat (Y-STR) loci in 885 unrelated Chinese Han male individuals from Guangdong Province, using a domestic AGCU Y24 STR kit. A total of 878 different haplotypes were observed at the 24 Y-STR loci; among them, 871 haplotypes were unique and 7 haplotypes occurred twice. The overall haplotype diversity was 0.99998 and the discrimination capacity was 99.2 %. The gene diversity values ranged from 0.4354 at DYS438 to 0.9606 at DYS385a/b. Population relationships between the Guangdong Han population and seven other published Chinese populations were evaluated by Rst values and visualized in a two multi-dimensional scaling plot. The results showed the 24 Y-STR loci are highly polymorphic in Guangdong Han population and of great value in forensic application.

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References

  1. Dou XL, Wang Y, Liu H, Peng S, Sun HY, Liu C (2014) Genetic polymorphisms of 24 Y-STR loci in Han population from Guangdong Province and its application in forensic medicine. New Med 12:796–800

    Google Scholar 

  2. Shi M, Liu Y, Zhang J, Bai R, Lv X, Ma S (2015) Analysis of 24 Y chromosomal STR haplotypes in a Chinese Han population sample from Henan Province, Central China. Forensic Sci Int Genet 17:83–86

    Article  CAS  Google Scholar 

  3. Zhu BF, Zhang YD, Liu WJ, Meng HT, Yuan GL, Lv Z, Dong N, Li Q, Yang CH, Zhang YH, Hou YL, Qian L, Fan SL, Xu P (2014) Genetic diversity and haplotype structure of 24 Y-chromosomal STR in Chinese Hui ethnic group and its genetic relationships with other populations. Electrophoresis 35:1993–2000

    Article  CAS  Google Scholar 

  4. Liu WJ, Pu HW, Yang CH, Meng HT, Zhang YD, Zhang LP, Yan JW, Wang HD, Ren JW, Sun JY, Liu C, Wang H, Zhu BF (2015) 24 Y-chromosomal STR haplotypic polymorphisms for Chinese Uygur ethnic group and its phylogenic analysis with other Chinese groups. Electrophoresis 36:626–632

    Article  CAS  Google Scholar 

  5. Ou X, Wang Y, Liu C, Yang D, Zhang C, Deng S, Sun H (2015) Haplotype analysis of the polymorphic 40 Y-STR markers in Chinese populations. Forensic Sci Int Genet 19:255–262

    Article  CAS  Google Scholar 

  6. Walsh PS, Metzger DA, Higushi R (2013) Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques 54:134–139

    Article  CAS  Google Scholar 

  7. Gusmao L, Butler JM, Carracedo A, Gill P, Kayser M, Mayr WR, Morling N, Prinz M, Roewer L, Tyler-Smith C, Schneider PM (2006) DNA commission of the international society of forensic genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis. Int J Legal Med 120:191–200

    Article  CAS  Google Scholar 

  8. Willuweit S, Roewer L (2015) The new Y chromosome haplotype reference database. Forensic Sci Int Genet 15:43–48

    Article  CAS  Google Scholar 

  9. Coble MD, Hill CR, Butler JM (2013) Haplotype data for 23 Y-chromosome markers in four U.S. population groups. Forensic Sci In Genet 7:e66–e68

    Article  CAS  Google Scholar 

  10. Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10:564–567

    Article  Google Scholar 

  11. Ye Y, Gao J, Fan G, Liao L, Hou Y (2015) Population genetics for 23 Y-STR loci in Tibetan in China and confirmation of DYS448 null allele. Forensic Sci Int Genet 16:e7–e10

    Article  CAS  Google Scholar 

  12. Poetsch M, Bajanowski T, Pfeiffer H (2012) The publication of population genetic data in the International Journal of Legal Medicine: guidelines. Int J Legal Med 126:489–490

    Article  Google Scholar 

Download references

Acknowledgments

This study was supported by the National Natural Science Foundation of China (81273347) and Guangdong Key Laboratory of Forensic Genetics (Project No. 2013B021500010).

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Authors and Affiliations

  1. Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People’s Republic of China

    Ying Wang, Chu-chu Zhang, Ran Li, Xue-ling Ou, Hai-xia Li & Hong-yu Sun

  2. Guangdong Provincial Key Laboratory of Forensic Genetics, Guangzhou, 510030, People’s Republic of China

    Chao Liu & Hong Liu

  3. Guangzhou Institute for Criminal Science and Technology, Guangzhou, 510030, People’s Republic of China

    Chao Liu & Hong Liu

Authors
  1. Ying Wang
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  2. Chao Liu
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  3. Chu-chu Zhang
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  4. Ran Li
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  5. Hong Liu
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  6. Xue-ling Ou
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  7. Hai-xia Li
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  8. Hong-yu Sun
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Corresponding author

Correspondence to Hong-yu Sun.

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Informed consent was obtained from all participants prior to participation in this study. This study was performed in accordance with the ethical guidelines specified by Zhongshan School of Medicine.

Conflict of interest

The authors declare that they have no competing interests.

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Wang, Y., Liu, C., Zhang, Cc. et al. Analysis of 24 Y-STR haplotype data in a Chinese Han population from Guangdong Province. Int J Legal Med 130, 689–691 (2016). https://doi.org/10.1007/s00414-015-1301-4

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  • DOI: https://doi.org/10.1007/s00414-015-1301-4

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