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Utility of diffusion-weighted magnetic resonance imaging in the diagnosis of cholesteatoma and the influence of the learning curve

  • Otology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Objective

The aim of this study is to assess the usefulness and reliability of this technique in our center, correlating the radiological and surgical findings and to study the influence of the learning curve by comparing the initial results with a radiological analysis performed 3 years after.

Study design

Retrospective cohort study.

Methods

67 patients with clinical cholesteatoma suspicion were included in the study, 24 with previously not operated cholesteatoma and 43 with suspicion of recurrent or residual cholesteatoma. All of them underwent diffusion-weighted magnetic resonance imaging, comparing these results with the histological confirmation after surgery. At 3 years, a blind radiological review of these cases was performed and the results were compared with those obtained after the first assessment to objectify the influence of the learning curve.

Results

The sensitivity, specificity, positive predictive value, and negative predictive value of the total sample were 93.9, 77.8, 92 and 82.4. The overall results after the blind review of the cases were 95.9, 94.4, 97.9 and 89.5, respectively.

Conclusion

The diffusion-weighted magnetic resonance imaging is a very useful technique during the diagnostic process of doubtful cases of cholesteatoma, especially in cases of follow-up. As for the influence of the learning curve, we observed a clear improvement in the specificity of the test.

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Authors and Affiliations

  1. Department of Otorhinolaryngology-Head and Neck Surgery, Donostia University Hospital, Donostia-San Sebastián, Spain

    Leire Garcia-Iza, Ane Ugarte, Juan Jose Navarro, Miren Goiburu & Xabier Altuna

  2. Department of Radiology, Osatek, Donostia-San Sebastián, Spain

    Amaia Guisasola

Authors
  1. Leire Garcia-Iza
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  2. Amaia Guisasola
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  3. Ane Ugarte
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  4. Juan Jose Navarro
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  5. Miren Goiburu
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  6. Xabier Altuna
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Corresponding author

Correspondence to Leire Garcia-Iza.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any added study with human participants performed by any of the authors. Nevertheless, ethics committee approval was granted. This observational study will be carried out in accordance with the ethical requirements of the Helsinki Declarations.

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Garcia-Iza, L., Guisasola, A., Ugarte, A. et al. Utility of diffusion-weighted magnetic resonance imaging in the diagnosis of cholesteatoma and the influence of the learning curve. Eur Arch Otorhinolaryngol 275, 2227–2235 (2018). https://doi.org/10.1007/s00405-018-5074-5

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  • DOI: https://doi.org/10.1007/s00405-018-5074-5

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