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The effects of septoplasty surgery on serum oxidative stress levels

  • Rhinology
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A Letter to the Editor to this article was published on 15 July 2017

Abstract

The aim of this study is to compare the total antioxidant status (TAS), total oxidant status (TOS), and paraoxonase (PON1) serum levels in patients who have undergone septoplasty (NSD). Forty-six patients (mean age 33.7) aged between 18 and 50 years who were diagnosed with nasal septal deviation (NSD) were included in the study. The TAS, TOS, and PON1 levels were compared in the serum samples obtained 1 month before the septoplasty and 3 months after surgery. There was a significant increase in mean TAS after septoplasty (1.041 vs. 1.124 mmol/L, p = 0.011). The mean TOS decreased significantly after septoplasty (20.631 vs. 5.946 mmol/L, p = 0.011). The mean pre- and postoperative PON1 levels were similar (326.93 ± 215.22 vs. 275.20 ± 167.76 U/L, p = 0.253). Increased TAS and decreased TOS after septoplasty show that patients with NSD are under oxidative stress that is relieved following septoplasty.

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Acknowledgements

The study protocol was approved by Gaziosmanpaşa University, Ethics Committee for Clinical Research (Decree No.: 15-KAEK-192).

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Authors and Affiliations

  1. Department of Otorhinolaryngology Head and Neck Surgery, Hitit University, üctutlar mah.ahcılar 16.sokak. Ada apt.10/15, 19000, Corum, Turkey

    Adnan Ekinci, Duran Karataş, Abdurrahman Yetiş & Muge Ozcan

  2. Department of Biostatistics, Faculty of Medicine, Hitit University, Corum, Turkey

    Emre Demir

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  1. Adnan Ekinci
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  2. Duran Karataş
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  3. Abdurrahman Yetiş
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  4. Emre Demir
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  5. Muge Ozcan
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Correspondence to Adnan Ekinci.

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The authors declared that there was no conflict of interest.

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Ekinci, A., Karataş, D., Yetiş, A. et al. The effects of septoplasty surgery on serum oxidative stress levels. Eur Arch Otorhinolaryngol 274, 2799–2802 (2017). https://doi.org/10.1007/s00405-017-4546-3

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  • DOI: https://doi.org/10.1007/s00405-017-4546-3

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