Skip to main content

Advertisement

SpringerLink
Log in

Does 3D laparoscopic video technology affect long-term survival in right hemicolectomy for cancer compared to standard 2D? A propensity score study

  • STUDY PROTOCOL
  • Published:
International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Background

There are few studies focused on the short-term results of laparoscopic right hemicolectomy performed with 2D (two-dimension) or 3D (three-dimension) video technology and none on the oncologic effects. The aim of the study was to assess the long-term results of laparoscopic right hemicolectomy (LRH) with intracorporeal anastomosis using 3D or 2D video in patients with right colon cancer with at least three years of oncologic follow-up.

Methods

Data from patients undergoing laparoscopic right hemicolectomy (LRH) with intracorporeal anastomosis for cancer in an 11-year period (June 2008–June 2019) and ≥ 3 years of follow-up were prospectively collected. Surgical procedures were performed by two expert laparoscopic surgeons.

Results

111 patients were included in the study: 56 (50.5%) in the 3D group and 55 (49.5%) in the 2D group. Tumor stage and number of lymph nodes harvested were similar. Overall and disease-free survival were not different in the two groups. Local recurrence occurred in none of the patients, and distant metachronous metastases were similar in the two groups. A propensity score weighting approach was used to account for potential confounding related to patients’ nonrandom allocation to the 2 groups. The effects of the intervention on postoperative outcomes were assessed with a weighted regression approach.

Conclusions

Laparoscopic 3D technology allows similar oncological results as 2D vision in LRH with intracorporeal anastomosis. Larger prospective randomized studies might confirm these results in the long-term follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

Data Availability

Data available upon request.

References

  1. Colon Cancer Laparoscopic or Open Resection Study Group et al (2009) Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol 10:44–52

    Article  PubMed  Google Scholar 

  2. Lacy AM et al (2008) The long-term results of a randomized clinical trial of laparoscopy-assisted versus open surgery for colon cancer. Ann Surg 248:1–7

    Article  PubMed  Google Scholar 

  3. Herron DM, Lantis JC II, Maykel J, Basu C, Schwaitzberg SD (1999) The 3-D monitor and head-mounted display: a quantitative evaluation of advanced laparoscopic viewing technologies. Surg Endosc 13:751–755

    Article  CAS  PubMed  Google Scholar 

  4. Mueller MD, Camartin C, Dreher E, Hänggi W (1999) Three-dimensional laparoscopy. Gadget or progress? A randomized trial on the efficacy of three-dimensional laparoscopy. Surg Endosc 13:469–472

    Article  CAS  PubMed  Google Scholar 

  5. Usta TA et al (2015) An assessment of the new generation three-dimensional high definition laparoscopic vision system on surgical skills: a randomized prospective study. Surg Endosc 29:2305–2313

    Article  PubMed  Google Scholar 

  6. Anania G et al (2020) Laparoscopic right hemicolectomy: the SICE (Società Italiana di Chirurgia Endoscopica e Nuove Tecnologie) network prospective trial on 1225 cases comparing intra corporeal versus extra corporeal ileo-colic side-to-side anastomosis. Surg Endosc 34:4788–4800

    Article  PubMed  Google Scholar 

  7. Tao K, Liu X, Deng M, Shi W, Gao J (2016) Three-dimensional against 2-dimensional laparoscopic colectomy for right-sided colon c7ancer. Surg Laparosc Endosc Percutan Tech 26:324–327

    Article  PubMed  Google Scholar 

  8. Currò G, Cogliandolo A, Bartolotta M, Navarra G (2016) Three-dimensional versus two-dimensional laparoscopic right hemicolectomy. J Laparoendosc Adv Surg Tech A 26:213–217

    Article  PubMed  Google Scholar 

  9. Bracale U et al (2020) Does a 3D laparoscopic approach improve surgical outcome of mininvasive right colectomy? A retrospective case-control study. Updat Surg 72:445–451

    Article  Google Scholar 

  10. Costa G et al (2021) 2D vs 3D laparoscopic right colectomy: a propensity score-matching comparison of personal experience with systematic review and meta-analysis. World J Gastrointest Surg 13:597–619

    Article  PubMed  PubMed Central  Google Scholar 

  11. Portale G, Pedon S, Benacchio L, Cipollari C, Fiscon V (2020) Two-dimensional (2-D) vs. three-dimensional (3-D) laparoscopic right hemicolectomy with intracorporeal anastomosis for colon cancer: comparison of short-term results. Surg Endosc 35:5279–5286

    Article  PubMed  Google Scholar 

  12. Benedetto U, Head SJ, Angelini GD, Blackstone EH (2018) Statistical primer: propensity score matching and its alternatives. Eur J Cardio-Thorac Surg Off J Eur Assoc Cardio-Thorac Surg 53:1112–1117

    Article  Google Scholar 

  13. Imai K, Ratkovic M (2014) Covariate balancing propensity score. J R Stat Soc 76:243–263

    Article  Google Scholar 

  14. Williamson EJ, Forbes A, White IR (2014) Variance reduction in randomised trials by inverse probability weighting using the propensity score. Stat Med 33:721–737

    Article  PubMed  Google Scholar 

  15. Conover MM et al (2021) Propensity score trimming mitigates bias due to covariate measurement error in inverse probability of treatment weighted analyses: a plasmode simulation. Stat Med 40:2101–2112

    Article  PubMed  Google Scholar 

  16. Cole SR, Hernán MA (2004) Adjusted survival curves with inverse probability weights. Comput Methods Programs Biomed 75:45–49

    Article  PubMed  Google Scholar 

  17. R Core Team (2021) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. https://www.R-project.org/. Accessed 1 Sept 2022

  18. Greifer N (2022) WeightIt: Weighting for covariate balance in observational studies. https://ngreifer.github.io/WeightIt/, https://github.com/ngreifer/WeightIt. Accessed 1 Sept 2022

  19. Greifer N (2022) Cobalt: covariate balance tables and plots. R package version 4.3.2. https://CRAN.R-project.org/package&20=%20cobalt. Accessed 1 Sept 2022

  20. Sjoberg DD, Whiting K, Curry M, Lavery JA, Larmarange J (2021) Reproducible summary tables with the gtsummary Package. R J 13:570

    Article  Google Scholar 

  21. Therneau T (2022) A package for survival analysis in R. R package version 3.3–1. https://CRAN.R-project.org/package%20=%20survival. Accessed 1 Sept 2022

  22. Kassambara A, Kosinski, M, Biecek P (2021) Survminer: Drawing Survival Curves using ‘ggplot2’. R package version 0.4.9. https://CRAN.R-project.org/package%20=%20survminer. Accessed 1 Sept 2022

  23. Feng X et al (2015) 3-Dimensional (3D) laparoscopy improves operating time in small spaces without impact on hemodynamics and psychomental stress parameters of the surgeon. Surg Endosc 29:1231–1239

    Article  PubMed  Google Scholar 

  24. Vettoretto N et al (2018) Three-dimensional versus two-dimensional laparoscopic right colectomy: a systematic review and meta-analysis. Int J Colorectal Dis 33:1799–1801

    Article  PubMed  Google Scholar 

  25. Arezzo A et al (2019) The use of 3D laparoscopic imaging systems in surgery: EAES consensus development conference 2018. Surg Endosc 33:3251–3274

    Article  PubMed  Google Scholar 

  26. Miyamoto Y et al (2020) Postoperative complications are associated with poor survival outcome after curative resection for colorectal cancer: a propensity-score analysis. J Surg Oncol 122:344–349

    Article  PubMed  Google Scholar 

  27. Cienfuegos JA et al (2015) Impact of perineural and lymphovascular invasion on oncological outcomes in rectal cancer treated with neoadjuvant chemoradiotherapy and surgery. Ann Surg Oncol 22:916–923

    Article  CAS  PubMed  Google Scholar 

  28. Le Voyer TE et al (2003) Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol Off J Am Soc Clin Oncol 21:2912–2919

    Article  Google Scholar 

  29. Amato A, Pescatori M (2006) Perioperative blood transfusions and recurrence of colorectal cancer. Cochrane Database Syst Rev 2011

  30. Gunka I, Dostalik J, Martinek L, Gunkova P, Mazur M (2013) Impact of blood transfusions on survival and recurrence in colorectal cancer surgery. Indian J Surg 75:94–101

    Article  PubMed  Google Scholar 

  31. Mörner MEM, Gunnarsson U, Jestin P, Svanfeldt M (2012) The importance of blood loss during colon cancer surgery for long-term survival: an epidemiological study based on a population based register. Ann Surg 255:1126–1128

    Article  PubMed  Google Scholar 

  32. Yang Y-W et al (2022) Three-dimensional versus conventional two-dimensional laparoscopic colectomy for colon cancer: a 3-year follow-up study. J Minimal Access Surg 18:289–294

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of General Surgery, Azienda Euganea ULSS 6, Cittadella, Italy

    Giuseppe Portale, Roberto Marconato & Valentino Fiscon

  2. Department of General Surgery, University of Ferrara, Ferrara, Italy

    Sabrina Pedon

  3. Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Padova, 35121, Italy

    Patrizia Bartolotta & Dario Gregori

  4. Department of Oncology, Azienda Euganea ULSS 6, Cittadella, Italy

    Alberto Morabito & Teodoro Sava

Authors
  1. Giuseppe Portale
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Roberto Marconato
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sabrina Pedon
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Patrizia Bartolotta
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Dario Gregori
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Alberto Morabito
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Teodoro Sava
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Valentino Fiscon
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Giuseppe Portale, Roberto Marconato, and Sabrina Pedon conceptualized the study and prepared the first draft of the manuscript. Patrizia Bartolotta and Dario Gregori performed the data analysis. Alberto Morabito and Teodoro Sava participated in the analysis and contributed to editing the manuscript. Valentino Fiscon contributed to the revision and editing of the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.

Corresponding author

Correspondence to Giuseppe Portale.

Ethics declarations

Conflict of interest

The authors declare no competing interests.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (JPG 214 kb)

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Portale, G., Marconato, R., Pedon, S. et al. Does 3D laparoscopic video technology affect long-term survival in right hemicolectomy for cancer compared to standard 2D? A propensity score study. Int J Colorectal Dis 38, 6 (2023). https://doi.org/10.1007/s00384-022-04297-2

Download citation

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00384-022-04297-2

Keywords

Search

Navigation