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Different information by MRI compare to ultrasound in fetal intracranial space occupying lesions

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Abstract

Purpose

The purpose of this study was to evaluate the value of prenatal magnetic resonance imaging (MRI) in characterizing fetal intracranial space occupying lesions in comparison to prenatal ultrasound.

Methods

This retrospective study included 50 fetuses (mean age 26 years, mean gestational weeks 31 + 1 GW) with intracranial space occupying lesions, suspected by prenatal screening ultrasound. T2-weighted, T1-weighted, SSFP, and diffusion-weighted sequences of the fetal brain were obtained on a 1.5 T unit. Pathology (n = 5), postmortem MRI (n = 3), or postnatal US (n = 42) was available as standard of reference.

Results

The fetal MRI provided correct diagnosis in 49 cases (98%), while 35 (70%) by ultrasound, and MRI failed in 1 case (2%), while ultrasound failed in 15 cases (30%). Fetal MR and ultrasound were concordant in 35 of 50 cases (70%), completely discordant in 4 (8%), and partially discordant in 11 (22%) cases.

Conclusions

MRI could provide detailed information about the minor lesions, such as focal hemorrhage and periventricular nodules. Meanwhile, it could provide whole view of the lesion in order to delineate the surrounding anatomical structure. But there are still some limitations of its soft-tissue resolution in a case with teratoma; more effort is needed to improve the sequences.

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Authors and Affiliations

  1. College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China

    Wei Xia & Peng Xiao

  2. Department of Radiology, Hubei Maternal and Children’s Hospital, Wuluolu 745, Hongshan District, Wuhan, 430070, China

    Wei Xia & Wenzhong Yang

  3. Department of Biomedical Imaging and Image-Guided Therapy, Division of Neuroradiology and Musculoskeletal Radiology, Medical University Vienna, A-1090, Vienna, Austria

    Gregor Kasprian

  4. Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

    Daoyu Hu

  5. Department of Ultrasound, Hubei Maternal and Children’s Hospital, Wuhan, 430070, China

    Xinlin Chen

Authors
  1. Wei Xia
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  2. Gregor Kasprian
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  3. Daoyu Hu
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  4. Peng Xiao
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Corresponding author

Correspondence to Wei Xia.

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Funding

This work was supported by a grant from the Hubei Institution of Science and Technology, China, and Hubei Province Natural Science Foundation Key Project, [grand number 2011CDA012]. The work is the responsibility of the authors. The funding organization had no role in study design, data collection, data analysis, manuscript preparation, and publication decision.

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Xia, W., Kasprian, G., Hu, D. et al. Different information by MRI compare to ultrasound in fetal intracranial space occupying lesions. Childs Nerv Syst 33, 2129–2136 (2017). https://doi.org/10.1007/s00381-017-3505-z

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  • DOI: https://doi.org/10.1007/s00381-017-3505-z

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