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Fetal MRI demonstrates glioependymal cyst in a case of sonographic unilateral ventriculomegaly

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Abstract

We report a fetus of 28 weeks′ gestation in which ultrasonography demonstrated unilateral ventriculomegaly and microcephaly. Fetal MRI demonstrated a simple, left paramedian occipital cyst with rarefaction of the corpus callosum and thinning of the adjacent cortical mantle. Ischaemia was suggested as the underlying pathogenesis, but autopsy after termination of pregnancy revealed a glioependymal cyst. This case highlights consideration of the rare diagnosis of glioependymal cyst when a cystic lesion associated with cerebral malformations, particularly dysgenesis of the corpus callosum, is demonstrated and fetal MRI suggests an ischaemic origin.

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Authors and Affiliations

  1. Department of Radiology, Charité-Universtitätsmedizin Berlin, Berlin, Germany

    Matthias R. Mühler

  2. Department of Neuropathology, Charité-Universtitätsmedizin Berlin Campus Virchow-Klinikum, Berlin, Germany

    Christian Hartmann

  3. Department of Clinical Genetics, Carl Gustav Carus University Medical Center, Dresden, Germany

    Walter Werner

  4. Department of Transfusion Medicine, Charité-Universtitätsmedizin Berlin Campus Virchow-Klinikum, Berlin, Germany

    Oliver Meyer

  5. Division of Prenatal Medicine, Charité-Universtitätsmedizin Berlin Campus Mitte, Berlin, Germany

    Rainer Bollmann

  6. Department of Neuroradiology, Charité-Universtitätsmedizin Berlin Campus Mitte, Berlin, Germany

    Randolf Klingebiel

  7. Laboratoire de Recherche en Imagerie (LRI), Faculté de Médecine Necker, Université Paris 5, 156 rue de Vaugirard, 75015, Paris, France

    Matthias R. Mühler

Authors
  1. Matthias R. Mühler
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  2. Christian Hartmann
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  3. Walter Werner
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  4. Oliver Meyer
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  5. Rainer Bollmann
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  6. Randolf Klingebiel
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Correspondence to Matthias R. Mühler.

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Mühler, M.R., Hartmann, C., Werner, W. et al. Fetal MRI demonstrates glioependymal cyst in a case of sonographic unilateral ventriculomegaly. Pediatr Radiol 37, 391–395 (2007). https://doi.org/10.1007/s00247-007-0419-z

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  • DOI: https://doi.org/10.1007/s00247-007-0419-z

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