Abstract
Objectives
To compare quantitative image quality parameters in abdominal dual-energy computed tomography angiography (DE-CTA) using an advanced image-based (Mono+) reconstruction algorithm for virtual monoenergetic imaging and standard DE-CTA.
Methods
Fifty-five patients (36 men; mean age, 64.2 ± 12.7 years) who underwent abdominal DE-CTA were retrospectively included. Mono + images were reconstructed at 40, 50, 60, 70, 80, 90 and 100 keV levels and as standard linearly blended M_0.6 images (60 % 100 kV, 40 % 140 kV). The contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) of the common hepatic (CHA), splenic (SA), superior mesenteric (SMA) and left renal arteries (LRA) were objectively measured.
Results
Mono+ DE-CTA series showed a statistically superior CNR for 40, 50, 60, 70 and 80 keV (P < 0.031) compared to M_0.6 images for all investigated arteries except SMA at 80 keV (P = 0.08). CNR at 40 keV revealed a mean relative increase of 287.7 % compared to linearly blended images among all assessed arteries (P < 0.001). SNR of Mono+ images was consistently significantly higher at 40, 50, 60 and 70 keV compared to M_0.6 for CHA and SA (P < 0.009).
Conclusions
Compared to linearly blended images, Mono+ reconstructions at low keV levels of abdominal DE-CTA datasets significantly improve quantitative image quality.
Key Points
• Mono+ combines increased attenuation with reduced image noise compared to standard DE-CTA.
• Mono+ shows superior contrast-to-noise ratios at low keV compared to linearly-blended images.
• Contrast-to-noise ratio in monoenergetic DE-CTA peaks at 40 keV.
• Mono+ reconstructions significantly improve quantitative image quality at low keV levels.
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Acknowledgments
The scientific guarantor of this publication is Dr. Julian L. Wichmann. The authors of this manuscript declare relationships with the following companies: Ralf W. Bauer is on the speakers' bureau of Siemens Healthcare, Computed Tomography division. The other authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article. The authors state that this work has not received any funding. One of the authors has significant statistical expertise. Institutional review board approval was obtained. Written informed consent was waived by the institutional review board. Approval from the institutional animal care committee was not required because animal subjects were not included in this study. No study subjects or cohorts have been previously reported. Methodology: retrospective, case–control study, performed at one institution.
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Albrecht, M.H., Scholtz, JE., Hüsers, K. et al. Advanced image-based virtual monoenergetic dual-energy CT angiography of the abdomen: optimization of kiloelectron volt settings to improve image contrast. Eur Radiol 26, 1863–1870 (2016). https://doi.org/10.1007/s00330-015-3970-2
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DOI: https://doi.org/10.1007/s00330-015-3970-2