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Prostatic Artery Embolization Allows to Maintain Full Sexual Activity in Patients Suffering from Bothersome Lower Urinary Tracts Symptoms related to Benign Prostatic Hyperplasia

  • CLINICAL INVESTIGATION
  • Embolisation (arterial)
  • Published:
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Abstract

Introduction

The effect of prostate artery embolization (PAE) on male sexual function is currently the subject of debate in the literature. The main purpose of this study was to define changes in all domains of sexual activity after PAE, using the international index of erectile function score (IIEF-15).

Methods

A single-center retrospective study was conducted on 129 patients (mean age of 65.5 ± 7 years), who underwent PAE from February 2014 to January 2017 for symptomatic benign prostatic hyperplasia (BPH). Fifty consecutive patients fulfilling the inclusion criteria were evaluated before and after PAE follow-up using the IIEF-15, IPSS, prostate volume (PV) and cardiovascular risk factor and BPH drugs. The IIEF-15 domains analyzed were: erectile function (EF) ejaculation and orgasm (Ej/O), sexual desire (SD), intercourse satisfaction (IS) and overall satisfaction (OS). A paired sample t test or Wilcoxon signed-rank test was used to compare IIEF-15 between baseline and follow-up.

Results

The study showed nonsignificant change in IIEF-15 total score (58.0 ± 13.8 SD; p = 0.71) and the five domains (EF 24.5 ± 7.0 SD, p = 0.82; EJ/O 8.2 ± 2.3 SD, p = 0.50; SD 7.2 ± 2.7 SD, p = 0.57; IS 10.3 ± 3.0 SD, p = 0.77; OS 8.2 ± 2.7 SD; p = 0.11) after PAE. We also found a significant improvement in IPSS score after PAE.

Conclusion

Based on the IIEF-15 questionnaire, PAE was showed to allow good urinary symptoms results and no deterioration in sexual function.

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Acknowledgements

I acknowledge the cooperation of all the staff of the Vascular and Oncological Interventional Radiology Department of the Hôpital Européen Georges Pompidou Paris who participated. We also appreciate the compliance of the patients.

Funding

This study was not supported by any funding.

Author information

Author notes

  1. Ludovica Marzano

    Present address: Istituto di Imaging della Svizzera Italiana, Ospedale Regionale Bellinzona e Valli, EOC, Bellinzona, Switzerland

Authors and Affiliations

  1. Faculté de Médecine, Université Paris V: René Descartes, Paris, France

    Nicolas Thiounn, Olivier Pellerin, Costantino Del Giudice & Marc Sapoval

  2. Vascular and Oncological Interventional Radiology Department Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France

    Ludovica Marzano, Olivier Pellerin, Costantino Del Giudice, Carol Dean & Marc Sapoval

  3. INSERM U970, Paris, France

    Olivier Pellerin, Carol Dean & Marc Sapoval

  4. Urology Department Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France

    Nicolas Thiounn & Charles Dariane

  5. Clinical Research Unit Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France

    Helena Pereira

  6. INSERM U1418, Paris, France

    Helena Pereira

  7. Hôpital Saint Louis, Paris, France

    Gregory Amouyal

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  1. Ludovica Marzano
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Corresponding authors

Correspondence to Ludovica Marzano or Marc Sapoval.

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The authors declare that they have no conflict of interest.

Ethical Approval

This study is a data collection. The patients were informed that their data could be used for research purposes and could refuse it. The data collection was approved by the CPP Ile de France 2 under the reference CERHUPO 2015-06-05.

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For this type of study, consent for publication is not required.

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Marzano, L., Thiounn, N., Pereira, H. et al. Prostatic Artery Embolization Allows to Maintain Full Sexual Activity in Patients Suffering from Bothersome Lower Urinary Tracts Symptoms related to Benign Prostatic Hyperplasia. Cardiovasc Intervent Radiol 43, 1202–1207 (2020). https://doi.org/10.1007/s00270-020-02520-7

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  • DOI: https://doi.org/10.1007/s00270-020-02520-7

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