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Effectiveness of the Conservative Therapy for Symptomatic Isolated Celiac Artery Dissection

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Abstract

Objective

To investigate the effectiveness of the conservative therapy for symptomatic isolated celiac artery dissection (ICAD).

Methods

Patients with symptomatic ICAD diagnosed on CT between February 2006 and June 2016 at three institutions were included.

Results

During the study period, a total of 24 patients (22 men, 2 women) were included in this retrospective study. Patients most commonly presented with epigastric pain (n = 21) or back pain (n = 3). Initial CT findings included celiac arterial calcification (n = 3); compression of the true lumen (n = 24), including stenosis of the true lumen <50% (n = 14) or ≥50% (n = 10); completely thrombosed (n = 11) or partially thrombosed (n = 5) false lumen; no thrombosis of the false lumen but presence of dissecting aneurysm (n = 8); and dissection extending to the common hepatic (n = 1) or splenic (n = 6) artery. Twenty-three patients recovered after conservative treatment, and one patient who failed conservative treatment recovered after surgical therapy. Of the 23 patients who received conservative treatment, complete or partial remodeling of ICAD was achieved in 18 (78.3%) and 5 (21.7%) patients during 22.1 ± 13.3 months of follow-up.

Conclusions

Conservative treatment can be applied successfully in most patients with symptomatic ICAD. Most cases of symptomatic ICAD resolve spontaneously within 2 years.

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Acknowledgements

We thank Megan Griffiths, Scientific Writer, Cleveland, OH, for her help with revising the manuscript.

Author information

Author notes

  1. Shaoqin Li, Lihua Cheng, Jianfei Tu, Yabin Jiao have contributed equally to this study.

Authors and Affiliations

  1. Department of Interventional Radiology, No. 2 People’s Hospital of Changzhou, Nanjing Medical University, Xing Long Road 29#, Changzhou, 213003, China

    Shaoqin Li, Lihua Cheng, Guomin Jiang & Zhongzhi Jia

  2. Department of Radiology and Interventional Radiology, Li Shui Central Hospital, Lishui, 323000, China

    Jianfei Tu, Xulu Wu & Dengke Zhang

  3. Department of Cardiovascular Surgery, China National Petroleum Corporation Central Hospital, Langfang, 065000, China

    Yabin Jiao

  4. Department of Radiology, No. 2 People’s Hospital of Changzhou, Changzhou, 213003, China

    Zhongling Wang

Authors
  1. Shaoqin Li
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  2. Lihua Cheng
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  3. Jianfei Tu
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  4. Yabin Jiao
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  5. Xulu Wu
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  6. Zhongling Wang
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  7. Dengke Zhang
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  8. Guomin Jiang
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  9. Zhongzhi Jia
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Corresponding author

Correspondence to Zhongzhi Jia.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964. Helsinki declaration and its later amendments or comparable ethical standards. For this retrospective study, formal consent to participate in this study was not required.

Funding

This study was supported by the Natural Science Foundation of China (NO. 81401498), Jiangsu Provincial Medical Youth Talent, and the High-Level Medical Talents Training Project of Changzhou (NO. 2016CZBJ009). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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Li, S., Cheng, L., Tu, J. et al. Effectiveness of the Conservative Therapy for Symptomatic Isolated Celiac Artery Dissection. Cardiovasc Intervent Radiol 40, 994–1002 (2017). https://doi.org/10.1007/s00270-017-1680-7

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  • DOI: https://doi.org/10.1007/s00270-017-1680-7

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