Abstract
Introduction
Studying epidemiology of abdominal aortic aneurysms repairs is essential to prevent related deaths. Although outcomes are influenced by socioeconomic factors, there are no nationwide studies on these statistics in low-and-middle income countries. Therefore, we designed this study to evaluate abdominal aortic aneurysms repair rates, trends, costs, and in-hospital mortality in the Brazilian Public Health System, which exclusively insures over 160 million Brazilians.
Material and Methods
Retrospective cross-sectional population-based analysis of publicly available data referring to all abdominal aortic aneurysm repairs performed between 2008 and 2019 in Brazilian public hospitals.
Results
We observed a total of 13,506 abdominal aortic aneurysm repairs, of which 32% were emergency endovascular repairs, 20% emergency open repairs, 32% elective endovascular repairs and 16% elective open repairs. There has been a downward trend in total abdominal aortic aneurysms repairs and an increasing predominance of endovascular repair. Elective and endovascular repairs were significantly associated with lower in-hospital mortality. For ruptured abdominal aortic aneurysms, we observed mortality rates of 13.8% after endovascular repair and 52.1% after open repair. For intact abdominal aortic aneurysms, we observed mortalities of 3.8% after endovascular repair and 18.6% after open repair. Procedure and mortality rates varied significantly among the Brazilian regions.
Conclusions
We observed a low and decreasing rate of abdominal aortic aneurysm repair. Most repairs were emergency and endovascular and there was an increasing predominance of endovascular repair. Endovascular and elective repairs were associated with lower mortality.
Similar content being viewed by others
References
Santo AH, Puech-Leão P, Krutman M (2021) Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000–2016: a multiple-cause-of-death study. Clinics 76:e2388. https://doi.org/10.6061/clinics/2021/e2388
Apoloni RC, Zerati AE, Wolosker N et al (2019) Analysis of the correlation between central obesity and abdominal aortic diseases. Ann Vasc Surg 54:176–184. https://doi.org/10.1016/j.avsg.2018.06.016
Wanhainen A, Hultgren R, Linné A et al (2016) Outcome of the swedish nationwide abdominal aortic aneurysm screening program. Circulation 134:1141–1148. https://doi.org/10.1161/CIRCULATIONAHA.116.022305
Montreuil B, Brophy J (2008) Screening for abdominal aortic aneurysms in men: a Canadian perspective using Monte Carlo-based estimates. Can J Surg J Can Chir 51:23–34
The Japanese Society for Vascular Surgery Database Management Committee Member, NCD Vascular Surgery Data Analysis Team (2020) Vascular surgery in japan: 2014 annual report by the japanese society for vascular surgery. Ann Vasc Dis 13:474–493. https://doi.org/10.3400/avd.ar.20-00128
Howell SJ (2017) Abdominal aortic aneurysm repair in the United Kingdom: an exemplar for the role of anaesthetists in perioperative medicine. Br J Anaesth 119:i15–i22. https://doi.org/10.1093/bja/aex360
Zommorodi S, Leander K, Roy J et al (2018) Understanding abdominal aortic aneurysm epidemiology: socioeconomic position affects outcome. J Epidemiol Community Health 72:904–910. https://doi.org/10.1136/jech-2018-210644
Ministry of Health of Brazil Agência Nacional de Saúde Suplementar-National Supplementary Health Agency. https://www.gov.br/ans/pt-br. Accessed 13 Sep 2021
Instituto Brasileiro de Geografia e Estatística Painel de Indicadores|IBGE. https://www.ibge.gov.br/indicadores.html. Accessed 16 Jul 2021
Ministry of Health of Brazil DATASUS. http://www2.datasus.gov.br/DATASUS/index.php?area=02. Accessed 15 Jul 2021
Universal Public Health System (SUS) of Brazil Autorizações de Internação Hospitalar aprovadas. In: FIOCRUZ. http://tabnet.fiocruz.br/dhx.exe?observatorio/tb_aih.def. Accessed 15 Jul 2021
The World Bank Group World Bank Group-International Development, Poverty, & Sustainability. https://www.worldbank.org/en/home. Accessed 16 Jul 2021
Dansey KD, de Guerre LEVM, Swerdlow NJ et al (2021) A comparison of administrative data and quality improvement registries for abdominal aortic aneurysm repair. J Vasc Surg 73:874–888. https://doi.org/10.1016/j.jvs.2020.06.105
Sampson UKA, Norman PE, Fowkes FGR et al (2014) Estimation of global and regional incidence and prevalence of abdominal aortic aneurysms 1990 to 2010. Glob Heart 9:159. https://doi.org/10.1016/j.gheart.2013.12.009
Dua A, Kuy S, Lee CJ et al (2014) Epidemiology of aortic aneurysm repair in the United States from 2000 to 2010. J Vasc Surg 59:1512–1517. https://doi.org/10.1016/j.jvs.2014.01.007
Trenner M, Kuehnl A, Reutersberg B et al (2018) Nationwide analysis of risk factors for in-hospital mortality in patients undergoing abdominal aortic aneurysm repair. Br J Surg 105:379–387. https://doi.org/10.1002/bjs.10714
Karthikesalingam A, Vidal-Diez A, Holt PJ et al (2016) Thresholds for abdominal aortic aneurysm repair in England and the USA. N Engl J Med 375:2051–2059. https://doi.org/10.1056/NEJMoa1600931
Choi C, Ahn S, Min S et al (2019) Nationwide epidemiologic study of abdominal aortic aneurysms in korea: a cross-sectional study using National Health Insurance Review And Assessment service data. Vasc Spec Int 35:193–201. https://doi.org/10.5758/vsi.2019.35.4.193
Jacomelli J, Summers L, Stevenson A et al (2016) Impact of the first 5 years of a national abdominal aortic aneurysm screening programme. Br J Surg 103:1125–1131. https://doi.org/10.1002/bjs.10173
Glover MJ, Kim LG, Sweeting MJ et al (2014) Cost-effectiveness of the national health service abdominal aortic aneurysm screening programme in England. Br J Surg 101:976–982. https://doi.org/10.1002/bjs.9528
Giardina S, Pane B, Spinella G et al (2011) An economic evaluation of an abdominal aortic aneurysm screening program in Italy. J Vasc Surg 54:938–946. https://doi.org/10.1016/j.jvs.2011.03.264
Dias-Neto M, Castro-Ferreira R, Mani K et al (2020) Nationwide analysis of ruptured abdominal aortic aneurysm in Portugal (2000–2015). Eur J Vasc Endovasc Surg 60:27–35. https://doi.org/10.1016/j.ejvs.2020.02.024
Dias-Neto M, Mani K, Leite-Moreira A et al (2020) Nationwide analysis of intact abdominal aortic aneurysm repair in Portugal from 2000 to 2015. Ann Vasc Surg 66:54-64.e1. https://doi.org/10.1016/j.avsg.2019.12.013
Melillo AM, Trani JL, Gaughan JP et al (2020) Assessing trends, morbidity, and mortality in ruptured abdominal aortic aneurysm repair with 9 years of data from the National Surgical Quality Improvement Program. J Vasc Surg 71:423–431. https://doi.org/10.1016/j.jvs.2019.04.462
Park BD, Azefor N, Huang C-C, Ricotta JJ (2013) Trends in treatment of ruptured abdominal aortic aneurysm: impact of endovascular repair and implications for future care. J Am Coll Surg 216:745–754. https://doi.org/10.1016/j.jamcollsurg.2012.12.028
Chen C-K, Chang H-T, Chen Y-C et al (2013) Surgeon elective abdominal aortic aneurysm repair volume and outcomes of ruptured abdominal aortic aneurysm repair: a 12 year nationwide study. World J Surg 37:2360–2371. https://doi.org/10.1007/s00268-013-2136-0
Yamaguchi T, Nakai M, Sumita Y et al (2019) Editor’s choice–endovascular repair versus surgical repair for japanese patients with ruptured thoracic and abdominal aortic aneurysms: a nationwide study. Eur J Vasc Endovasc Surg 57:779–786. https://doi.org/10.1016/j.ejvs.2019.01.027
Teivelis MP, Malheiro DT, Hampe M et al (2016) Endovascular repair of infrarenal abdominal aortic aneurysm results in higher hospital expenses than open surgical repair: evidence from a tertiary hospital in brazil. Ann Vasc Surg 36:44–54. https://doi.org/10.1016/j.avsg.2016.03.016
Mohan PP, Rozenfeld M, Kane RA et al (2012) Nationwide trends in abdominal aortic aneurysm repair and use of endovascular repair in the emergency setting. J Vasc Interv Radiol 23:338–344. https://doi.org/10.1016/j.jvir.2011.11.015
de Almeida MC, de Arruda MA, Teivelis MP et al (2017) Carbon dioxide as contrast medium to guide endovascular aortic aneurysm repair. Ann Vasc Surg 39:67–73. https://doi.org/10.1016/j.avsg.2016.06.028
Acknowledgements
We thank Rogerio Ruscitto do Prado, PhD, for his statistical consultation.
Funding
This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
No author has conflict of interest in this manuscript.
Ethical Approval
The Ethics Committee of the Hospital Israelita Albert Einstein approved the study (CAAE 35826320.2.0000.0071). Since we used a publicly available database with de-identified entries, a waiver of informed consent forms was requested and granted.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Louzada, A.C.S., da Silva, M.F.A., Portugal, M.F.C. et al. Epidemiology of Abdominal Aortic Aneurysm Repair in Brazil from 2008 to 2019 and Comprehensive Review of Nationwide Statistics Across the World. World J Surg 46, 1485–1492 (2022). https://doi.org/10.1007/s00268-022-06486-0
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00268-022-06486-0