Skip to main content

Advertisement

Log in

Evolving Indications for Lower Limb Amputations in South Africa Offer Opportunities for Health System Improvement

  • Scientific Review
  • Published:
World Journal of Surgery Aims and scope Submit manuscript

Abstract

Background

Rapid urbanization and westernization have precipitated dramatic changes in the profile and prevalence of surgical diseases in sub-Saharan Africa. Disease of lifestyle is now common. We aimed to review our experience with lower-limb amputations at our surgical service in South Africa.

Methods

A single-center retrospective review of a prospectively collected database was performed of all patients who underwent a lower limb amputation. Inferential and descriptive statistics were performed. Patient demographics, indication, type of amputation, and management were reviewed. The primary outcome was 30-day in-patient mortality rate.

Results

Over a 5-year period (2013–2018), 348 patients underwent lower limb amputations. The median age was 61.5 years. 53.7% were diabetic and 56.3% were hypertensive. 53.2% had associated peripheral vascular disease and 8% preexisting cardiac disease. 30.7% smoked. Guillotine below-knee amputation was frequently performed (44.5% of amputations). 16.1% of these patients required a further operation. The in-hospital mortality rate was 8%. Underlying renal disease was an independent risk factor for mortality (p = 0.004).

Conclusion

Currently, the most common indications for LLA in South Africa are diabetes mellitus and atherosclerosis. This reflects the changing pattern of disease in the country. There is a major problem with access to health care in rural areas in South Africa with significant delays in getting patients to tertiary units for evaluation by specialists. Foot care and prevention at a primary health care level is also lacking. Global improvements in the healthcare system are needed to improve LLA rates in South Africa.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Mayosi BM, Flisher AJ, Lalloo UG et al (2009) The burden of non-communicable diseases in South Africa. Lancet 374(9693):934–947

    Article  Google Scholar 

  2. Bradshaw D, Norman R, Pieterse D et al (2007) Estimating the burden of disease attributable to diabetes in South Africa in 2000. S Afr Med J 97(8):700–706

    PubMed  Google Scholar 

  3. Peer N, Steyn K, Lombard C et al (2012) Rising diabetes prevalence among urban-dwelling black South Africans. PLoS ONE 7(9):e43336

    Article  CAS  Google Scholar 

  4. Youth explorer organization census statistics. https://youthexplorer.org.za/profiles/province-KZN-kwazulu-natal/#poverty

  5. Conte MS, Pomposelli FB, Clair DG (2015) Society for vascular surgery practice guidelines for atherosclerotic occlusive disease of the lower extremities: management of asymptomatic disease and claudication. JVS 61:3S

    Google Scholar 

  6. World Health Organization (2006). Definition and diagnosis of diabetes mellitus and intermediate hyperglycaemia. WHO Press 2006

  7. World Health Organization (2013). A global brief on Hypertension. WHO Press 2013

  8. Sarfo-Kantanka O, Sarfo FS, Kyei I et al (2019) Incidence and determinants of diabetes-related lower limb amputations in Ghana, 2010–2015—a retrospective cohort study. BMC Endocr Disord 19(1):27

    Article  Google Scholar 

  9. Sarfo-Kantanka O, Kyei I, Mbanya JC et al (2018) Diabetes-related foot disorders among adult Ghanaians. Diabet Foot Ankle 9(1):1511678

    Article  Google Scholar 

  10. Gebreslassie B, Gebreselassie K, Ethiop Esayas R (2018) Patterns and causes of amputation in Ayder Referral Hospital, Mekelle, Ethiopia: a three-year experience. J Health Sci 28(1):31–36

    Google Scholar 

  11. Chalya PL, Mabula JB, Dass RM et al (2012) Major limb amputations: a tertiary hospital experience in northwestern Tanzania. J Orthop Surg Res 7:18

    Article  Google Scholar 

  12. Nwosu C, Babalola MO, Ibrahim MH et al (2017) Major limb amputations in a tertiary hospital in North Western Nigeria. Afr Health Sci 17(2):508–512

    Article  Google Scholar 

  13. Dabkana TM, Nyaku FT, Bwala ST (2018) Current indications for extremity amputations in Maiduguri, North-East Nigeria: a 6-year retrospective review. Ann Afr Med Jan–Mar 17(1):22–25

    Article  Google Scholar 

  14. ThanniL O, Tade AO (2007) Extremity amputation in Nigeria: a review of indications and mortality. Surgeon 5(4):213–217

    Article  Google Scholar 

  15. Forrester JD, Teslovich NC, Nigo L et al (2018) Undertreated Medical Conditions vs Trauma as primary indications for amputation at a Referral Hospital in Cameroon. JAMA Surg 153(9):858–860

    Article  Google Scholar 

  16. Manickum P, Ramklass SS, Madiba TE (2018) A Five-year audit of lower limb amputations below the knee and rehabilitation outcomes: the Durban experience. J Endocrinol Metab Diabetes S Afr 24(2):41–45

    Google Scholar 

  17. Godlwana L, Nadasan T, Puckree T (2008) Global trends in incidence of lower limb amputation: a review of the literature. S Afr J Physiother 64(1):8–12

    Article  Google Scholar 

  18. Dunbar GL, Hellenberg DA, Levitt NS (2010) Diabetes mellitus and non-traumatic lower extremity amputations in four public sector hospitals in Cape Town, South Africa, during 2009 and 2010. S Afr Med J 105(12):1053

    Article  Google Scholar 

  19. Cheddie S, Manneh CG, Pillay B (2018) Spectrum of disease and outcome of primary amputation for diabetic foot sepsis in rural KwaZulu-Natal. S Afr J Surg 56(3):16–19

    Article  CAS  Google Scholar 

Download references

Funding

No funding was utilized for this work.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Muhammad Zafar Khan.

Ethics declarations

Conflict of interest

The authors do not have any relevant disclosures or conflicts of interest in this work.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Khan, M.Z., Smith, M.T., Bruce, J.L. et al. Evolving Indications for Lower Limb Amputations in South Africa Offer Opportunities for Health System Improvement. World J Surg 44, 1436–1443 (2020). https://doi.org/10.1007/s00268-019-05361-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00268-019-05361-9

Navigation