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Stromal Vascular Fraction Gel (SVF-Gel) Combined with Nanofat for Tear Trough Deformity

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  • Fat Injection
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Abstract

Background

Tear trough deformity makes patients appear tired. Patients with less severe tear trough deformity prefer a less invasive method to correct the deformity. The infraorbital area is a multilayered tissue, and the aging of various components leads to tear trough deformity. To this end, we utilized the different characteristics of different fat derivatives to correct tear trough deformity.

Methods

Thirty-two patients with Barton Grade I/II tear trough deformity were enrolled in this study between September 2020 and March 2021. We injected Stromal Vascular Fraction Gel (SVF-Gel) into the suborbicularis oculi fat layer and Nanofat into the subcutaneous. After 12 months of follow-up, we evaluated the changes using standardized clinical photogrammetric techniques, volume, global aesthetic improvement scale, and patient self-evaluation.

Results

There were no major complications in any of the 32 patients. The measured data points demonstrated improvements in all aesthetic parameters. The width of the tear trough and the distance from the pupil to the tear trough improved. The Global Aesthetic Improvement Scale (GAIS) showed a high score (2.45±0.64 points), with patient self-assessment showing satisfactory results.

Conclusion

SVF-Gel combined with Nanofat injection can effectively correct tear trough deformities.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

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Acknowledgments

We thank all the patients, who participated in this study. The work is supported by National Natural Science Foundation of China (81501571).

Funding

The authors have no financial interest in any of the products or devices mentioned in this article.

Author information

Authors and Affiliations

  1. Department of Wound Reconstructive Surgery, Tongji Hospital, Tongji University, Shanghai, China

    Yiyu Sun & Tao Dai

  2. Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhi Zao Ju Road, Shanghai, China

    Gaoyang Wu, Shengli Li, Weigang Cao & Tingting Dai

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  1. Yiyu Sun
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Correspondence to Weigang Cao or Tingting Dai.

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Ethics approval

The study was approved by the Ethics Research Committee of Shanghai Ninth People’s Hospital (SH9H-2022-TK365-1, Shanghai Jiaotong University, School of Medicine, Shanghai, China) and in accordance with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Written informed consent was obtained from all the participants

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Yiyu Sun and Gaoyang Wu contributed equally to this article and should be considered co-first authors.

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Sun, Y., Wu, G., Dai, T. et al. Stromal Vascular Fraction Gel (SVF-Gel) Combined with Nanofat for Tear Trough Deformity. Aesth Plast Surg 48, 213–220 (2024). https://doi.org/10.1007/s00266-023-03698-0

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