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Clinical approach to patients with an ileal pouch

  • Special Section: Ileal Pouch
  • Published:
Abdominal Radiology Aims and scope Submit manuscript

Abstract

Restorative proctocolectomy with ileal pouch–anal anastomosis is the procedure of choice to maintain intestinal continuity when a total proctocolectomy is a required. It is a technically challenging operation that may be burdened by several nuanced complications both in the immediate postoperative period and in the long term. Most patients with a pouch and any kind of complication will undergo radiological studies, thus multidisciplinary collaboration between surgeons, gastroenterologists, and radiologists is paramount to their timely and accurate diagnosis. When treating pouch patients, radiologists should be familiar with regular pouch anatomy and its appearance in imaging studies, as well as with the most common complications that can occur in this population. In this review, we examine the clinical decision-making process at each step before and after pouch creation, as well as the most common complications associated with pouch surgery, their diagnosis, and their management.

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References

  1. Holubar SD, Lightner AL, Poylin V, et al. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Surgical Management of Ulcerative Colitis. Dis Colon Rectum. 2021;64:783–804.

    Article  PubMed  Google Scholar 

  2. Herzig D, Hardiman K, Weiser M, et al. The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Inherited Polyposis Syndromes. Dis Colon Rectum. 2017;60:881–894.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Lightner AL, Jia X, Zaghiyan K, et al. IPAA in Known Preoperative Crohn’s Disease: A Systematic Review. Dis Colon Rectum.;64 Available from: https://journals.lww.com/dcrjournal/Fulltext/2021/03000/IPAA_in_Known_Preoperative_Crohn_s_Disease__A.17.aspx. 2021.

  4. Abelson JS, Michelassi F, Mao J, et al. Higher surgical morbidity for ulcerative colitis patients in the era of biologics. Ann Surg. 2018;268:311–317.

    Article  PubMed  Google Scholar 

  5. Peyrin-Biroulet L, Germain A, Patel AS, et al. Systematic review: outcomes and post-operative complications following colectomy for ulcerative colitis. Aliment Pharmacol Ther. 2016;44:807–816.

    Article  CAS  PubMed  Google Scholar 

  6. Fazio VW, Kiran RP, Remzi FH, et al. Ileal Pouch Anal Anastomosis: Analysis of Outcome and Quality of Life in 3707 Patients. Ann Surg.;257 Available from: https://journals.lww.com/annalsofsurgery/Fulltext/2013/04000/Ileal_Pouch_Anal_Anastomosis__Analysis_of_Outcome.15.aspx. 2013.

  7. Heuthorst L, Wasmann KATGM, Reijntjes MA, et al. Ileal Pouch-anal Anastomosis Complications and Pouch Failure: A systematic review and meta-analysis. Ann Surg Open.;2 Available from: https://journals.lww.com/aosopen/Fulltext/2021/06000/Ileal_Pouch_anal_Anastomosis_Complications_and.19.aspx. 2021.

  8. Fazio VW, Tekkis PP, Remzi F, et al. Quantification of Risk for Pouch Failure After Ileal Pouch Anal Anastomosis Surgery. Ann Surg.;238 Available from: https://journals.lww.com/annalsofsurgery/Fulltext/2003/10000/Quantification_of_Risk_for_Pouch_Failure_After.16.aspx. 2003.

  9. Gorfine SR, Fichera A, Harris MT, et al. Long-term results of salvage surgery for septic complications after restorative proctocolectomy: does fecal diversion improve outcome? Dis Colon Rectum. 2003;46:1339–1344.

    Article  PubMed  Google Scholar 

  10. Sahami S, Bartels SAL, D’Hoore A, et al. A Multicentre Evaluation of Risk Factors for Anastomotic Leakage After Restorative Proctocolectomy with Ileal Pouch-Anal Anastomosis for Inflammatory Bowel Disease. J Crohns Colitis. 2016;10:773–778.

    Article  PubMed  Google Scholar 

  11. Farouk R, Dozois RR, Pemberton JH, et al. Incidence and subsequent impact of pelvic abscess after ileal pouch-anal anastomosis for chronic ulcerative colitis. Dis Colon Rectum. 1998;41:1239–1243.

    Article  CAS  PubMed  Google Scholar 

  12. Grainge MJ, West J, Card TR. Venous thromboembolism during active disease and remission in inflammatory bowel disease: a cohort study. Lancet. 2010;375:657–663.

    Article  PubMed  Google Scholar 

  13. Ball CG, MacLean AR, Buie WD, et al. Portal vein thrombi after ileal pouch-anal anastomosis: its incidence and association with pouchitis. Surg Today. 2007;37:552–557.

    Article  PubMed  Google Scholar 

  14. Baker ME, Remzi F, Einstein D, et al. CT depiction of portal vein thrombi after creation of ileal pouch-anal anastomosis. Radiology. 2003;227:73–79.

    Article  PubMed  Google Scholar 

  15. Syed A, Seoud T, Carleton NM, et al. Association Between Portal Vein Thrombosis and Pouchitis in Patients with Ulcerative Colitis. Dig Dis Sci. 2022;67:1303–1310.

    Article  PubMed  Google Scholar 

  16. Lian L, Serclova Z, Fazio VW, et al. Clinical Features and Management of Postoperative Pouch Bleeding after Ileal Pouch–Anal Anastomosis (IPAA). J Gastrointest Surg. 2008;12:1991–1994.

    Article  PubMed  Google Scholar 

  17. Murthy SK, Feuerstein JD, Nguyen GC, et al. AGA Clinical Practice Update on Endoscopic Surveillance and Management of Colorectal Dysplasia in Inflammatory Bowel Diseases: Expert Review. Gastroenterology. 2021;161:1043-1051.e4.

    Article  PubMed  Google Scholar 

  18. Church J. The Implications of Pouch Physiology. Dis Colon Rectum.;62.

  19. Quinn KP, Tse CS, Lightner AL, et al. Nonrelaxing Pelvic Floor Dysfunction Is an Underestimated Complication of Ileal Pouch-Anal Anastomosis. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2017;15:1242–1247.

    Google Scholar 

  20. Shashi P, Shen B. Characterization of megapouch in patients with restorative proctocolectomy. Surg Endosc. 2019;33:2293–2303.

    Article  PubMed  Google Scholar 

  21. Shen B, Sanmiguel C, Bennett AE, et al. Irritable pouch syndrome is characterized by visceral hypersensitivity. Inflamm Bowel Dis. 2011;17:994–1002.

    Article  PubMed  Google Scholar 

  22. Shen B, Kochhar GS, Rubin DT, et al. Treatment of pouchitis, Crohn’s disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium. Lancet Gastroenterol Hepatol. 2022;7:69–95.

    Article  CAS  PubMed  Google Scholar 

  23. Lightner AL, Fletcher JG, Pemberton JH, et al. Crohn’s Disease of the Pouch: A True Diagnosis or an Oversubscribed Diagnosis of Exclusion? Dis Colon Rectum.;60 Available from: https://journals.lww.com/dcrjournal/Fulltext/2017/11000/Crohn_s_Disease_of_the_Pouch__A_True_Diagnosis_or.14.aspx. 2017.

  24. Kirat HT, Remzi FH, Shen B, et al. Pelvic abscess associated with anastomotic leak in patients with ileal pouch-anal anastomosis (IPAA): transanastomotic or CT-guided drainage? Int J Colorectal Dis. 2011;26:1469–1474.

    Article  PubMed  Google Scholar 

  25. Shen B, Fazio VW, Remzi FH, et al. Risk factors for clinical phenotypes of Crohn’s disease of the ileal pouch. Am J Gastroenterol. 2006;101:2760–2768.

    Article  PubMed  Google Scholar 

  26. Heriot AG, Tekkis PP, Smith JJ, et al. Management and outcome of pouch-vaginal fistulas following restorative proctocolectomy. Dis Colon Rectum. 2005;48:451–458.

    Article  PubMed  Google Scholar 

  27. Sapci I, Akeel N, DeLeon MF, et al. What Is the Best Surgical Treatment of Pouch-Vaginal Fistulas? Dis Colon Rectum.;62 Available from: https://journals.lww.com/dcrjournal/Fulltext/2019/05000/What_Is_the_Best_Surgical_Treatment_of.13.aspx. 2019.

  28. Torkzad MR, Karlbom U. MRI for assessment of anal fistula. Insights Imaging. 2010;1:62–71.

    Article  PubMed Central  Google Scholar 

  29. Ashburn JH. Management of IPAA-Associated Persistent Presacral Sinus BT - Mastery of IBD Surgery. In: Hyman N, Fleshner P, Strong S, eds. Cham: Springer International Publishing:371–376.

  30. Khan F, Hull TL, Shen B. Diagnosis and management of floppy pouch complex. Gastroenterol Rep. 2018;6:246–256.

    Article  Google Scholar 

  31. Lan N, Wu J-J, Wu X-R, et al. Endoscopic treatment of pouch inlet and afferent limb strictures: stricturotomy vs. balloon dilation. Surg Endosc. 2021;35:1722–1733.

  32. Kirat HT, Kiran RP, Remzi FH, et al. Diagnosis and management of afferent limb syndrome in patients with ileal pouch-anal anastomosis. Inflamm Bowel Dis. 2011;17:1287–1290.

    Article  PubMed  Google Scholar 

  33. Joyce MR, Fazio VW, Hull TT, et al. Ileal pouch prolapse: prevalence, management, and outcomes. J Gastrointest Surg Off J Soc Surg Aliment Tract. 2010;14:993–997.

    Article  Google Scholar 

  34. Holubar S, Lightner A, Qazi T, et al. TWISTED POUCH SYNDROME - A DIFFICULT TO DIAGNOSE MECHANICAL COMPLICATION OF ILEAL POUCH-ANAL ANASTOMOSIS: OUTCOMES AFTER REDO POUCH PROCEDURES. Gastroenterology. 2021;160:S22–S23.

    Article  Google Scholar 

  35. Dionigi B, Prien C, Lavryk O, et al. Pouch volvulus-why adhesions are not always the enemy. Color Dis Off J Assoc Coloproctology Gt Britain Irel. 2022;24:1192–1196.

    Google Scholar 

  36. Fazio VW, Ziv Y, Church JM, et al. Ileal pouch-anal anastomoses complications and function in 1005 patients. Ann Surg. 1995;222:120–127.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  37. Liu Z, Kiran RP, Bennett AE, et al. Diagnosis and management of dysplasia and cancer of the ileal pouch in patients with underlying inflammatory bowel disease. Cancer. 2011;117:3081–3092.

    Article  PubMed  Google Scholar 

  38. Rossi C, Beyer-Berjot L, Maggiori L, et al. Redo ileal pouch-anal anastomosis: outcomes from a case-controlled study. Color Dis Off J Assoc Coloproctology Gt Britain Irel. 2019;21:326–334.

    CAS  Google Scholar 

  39. Rottoli M, Vallicelli C, Gionchetti P, et al. Transabdominal salvage surgery after pouch failure in a tertiary center: A case-matched study. Dig Liver Dis. 2018;50:446–451.

    Article  PubMed  Google Scholar 

  40. Schiergens TS, Hoffmann V, Schobel TN, et al. Long-term Quality of Life of Patients With Permanent End Ileostomy: Results of a Nationwide Cross-Sectional Survey. Dis Colon Rectum.;60 Available from: https://journals.lww.com/dcrjournal/Fulltext/2017/01000/Long_term_Quality_of_Life_of_Patients_With.9.aspx. 2017.

  41. Remzi FH, Aytac E, Ashburn J, et al. Transabdominal Redo Ileal Pouch Surgery for Failed Restorative Proctocolectomy: Lessons Learned Over 500 Patients. Ann Surg.;262 Available from: https://journals.lww.com/annalsofsurgery/Fulltext/2015/10000/Transabdominal_Redo_Ileal_Pouch_Surgery_for_Failed.15.aspx. 2015.

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Correspondence to Tracy L. Hull.

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Maspero, M., Hull, T.L. Clinical approach to patients with an ileal pouch. Abdom Radiol 48, 2918–2929 (2023). https://doi.org/10.1007/s00261-023-03888-z

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  • DOI: https://doi.org/10.1007/s00261-023-03888-z

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