Skip to main content

Advertisement

Log in

Static and dynamic CT imaging of the cervical spine in patients with rheumatoid arthritis

  • Scientific Article
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract

Objective

To compare CR with CT (static and dynamic) to evaluate upper spine instability and to determine if CT in flexion adds value compared to MR imaging in neutral position to assess compression of the subarachnoid space and of the spinal cord.

Materials and methods

Twenty-one consecutive patients with atlantoaxial subluxation due to rheumatoid arthritis planned for atlantoaxial fusion were included. CT and MRI were performed with the neck in the neutral position and CT also in flexion. CR in neutral position and flexion were obtained in all patients except for one subject who underwent examination in flexion and extension.

Results

CR and CT measurements of atlantoaxial subluxation correlated but were larger by CR than CT in flexion, however, the degree of vertical dislocation was similar with both techniques irrespective of the position of the neck. Cervical motion was larger at CR than at CT. The spinal cord compression was significantly worse at CT obtained in the flexed position as compared to MR imaging in the neutral position.

Conclusions

Functional CR remains the primary imaging method but CT in the flexed position might be useful in the preoperative imaging work-up, as subarachnoid space involvement may be an indicator for the development of neurologic dysfunction.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. Wasserman BR, Moskovich R, Razi AE. Rheumatoid arthritis of the cervical spine–clinical considerations. Bull NYU Hosp Jt Dis. 2011;69(2):136–48.

    PubMed  Google Scholar 

  2. Nguyen HV, Ludwig SC, Silber J, Gelb DE, Anderson PA, Frank L, et al. Rheumatoid arthritis of the cervical spine. Spine J Off J North Am Spine Soc. 2004;4(3):329–34.

    Article  Google Scholar 

  3. Younes M, Belghali S, Kriâa S, Zrour S, Bejia I, Touzi M, et al. Compared imaging of the rheumatoid cervical spine: prevalence study and associated factors. Jt Bone Spine. 2009;76(4):361–8.

    Article  Google Scholar 

  4. Riise T, Jacobsen BK, Gran JT. High mortality in patients with rheumatoid arthritis and atlantoaxial subluxation. J Rheumatol. 2001;28(11):2425–9.

    CAS  PubMed  Google Scholar 

  5. Casey AT, Crockard HA, Stevens J. Vertical translocation. Part II. Outcomes after surgical treatment of rheumatoid cervical myelopathy. J Neurosurg. 1997;87(6):863–9.

    Article  CAS  PubMed  Google Scholar 

  6. Casey AT, Crockard HA, Geddes JF, Stevens J. Vertical translocation: the enigma of the disappearing atlantodens interval in patients with myelopathy and rheumatoid arthritis. Part I. Clinical, radiological, and neuropathological features. J Neurosurg. 1997;87(6):856–62.

    Article  CAS  PubMed  Google Scholar 

  7. St Clair EW, van der Heijde DM, Smolen JS, Maini RN, Bathon JM, Emery P, et al. Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial. Arthritis Rheum. 2004;50(11):3432–43.

    Article  CAS  PubMed  Google Scholar 

  8. Goekoop–Ruiterman YPM, Leiden University Medical Center L, The Netherlands, Leiden University Medical Center PB, 2300 RC Leiden, The Netherlands, De Vries–Bouwstra JK, VU Medical Center A, The Netherlands, Allaart CF, et al. Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): A randomized, controlled trial. Arthritis Rheum 52(11):3381–90.

  9. Nishimoto N, University WM, University WM, norichan@wakayama-med.ac.jp, Ito K, Chugai Pharmaceutical Co. L, et al. Safety and efficacy profiles of tocilizumab monotherapy in Japanese patients with rheumatoid arthritis: meta-analysis of six initial trials and five long-term extensions. Modern Rheumatology. 2014; 20(3):222–32.

  10. Ostensen H, Gudmundsen TE, Haakonsen M, Lagerqvist H, Kaufmann C, Ostensen M. Three-dimensional CT evaluation of occipito-atlanto-axial dislocation in rheumatoid arthritis. Scand J Rheumatol. 1998;27(5):352–6.

    Article  CAS  PubMed  Google Scholar 

  11. Riew KD, Hilibrand AS, Palumbo MA, Sethi N, Bohlman HH. Diagnosing basilar invagination in the rheumatoid patient. The reliability of radiographic criteria. J Bone Joint Surg Am. 2001;83-A(2):194–200.

    CAS  PubMed  Google Scholar 

  12. Reijnierse M, Breedveld FC, Kroon HM, Hansen B, Pope TL, Bloem JL. Are magnetic resonance flexion views useful in evaluating the cervical spine of patients with rheumatoid arthritis? Skeletal Radiol. 2000;29(2):85–9.

    Article  CAS  PubMed  Google Scholar 

  13. Kauppi M, Neva MH. Sensitivity of lateral view cervical spine radiographs taken in the neutral position in atlantoaxial subluxation in rheumatic diseases. Clin Rheumatol. 1998;17(6):511–4.

    Article  CAS  PubMed  Google Scholar 

  14. Laiho K, Soini I, Kautiainen H, Kauppi M. Can we rely on magnetic resonance imaging when evaluating unstable atlantoaxial subluxation? Ann Rheum Dis. 2003;62(3):254–6.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  15. Dvorak J, Grob D, Baumgartner H, Gschwend N, Grauer W, Larsson S. Functional evaluation of the spinal cord by magnetic resonance imaging in patients with rheumatoid arthritis and instability of upper cervical spine. Spine (Phila Pa 1976). 1989; 14(10):1057–64.

  16. Allmann KH, Uhl M, Uhrmeister P, Neumann K, von Kempis J, Langer M. Functional MR imaging of the cervical spine in patients with rheumatoid arthritis. Acta Radiol. 1998;39(5):543–6.

    Article  CAS  PubMed  Google Scholar 

  17. Oostveen JC, Roozeboom AR, van de Laar MA, Heeres J, den Boer JA, Lindeboom SF. Functional turbo spin echo magnetic resonance imaging versus tomography for evaluating cervical spine involvement in rheumatoid arthritis. Spine (Phila Pa 1976). 1998; 23(11):1237–44.

  18. Karhu JO, Parkkola RK, Komu ME, Kormano MJ, Koskinen SK. Kinematic magnetic resonance imaging of the upper cervical spine using a novel positioning device. Spine. 1999;24(19):2046–56.

    Article  CAS  PubMed  Google Scholar 

  19. Svedmark P, Lundh F, Nemeth G, Noz ME, Maguire Jr GQ, Zeleznik MP, et al. Motion analysis of total cervical disc replacements using computed tomography: preliminary experience with nine patients and a model. Acta Radiol. 2011;52(10):1128–37.

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tomas Söderman.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Söderman, T., Olerud, C., Shalabi, A. et al. Static and dynamic CT imaging of the cervical spine in patients with rheumatoid arthritis. Skeletal Radiol 44, 241–248 (2015). https://doi.org/10.1007/s00256-014-2000-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-014-2000-9

Keywords

Navigation