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Chédiak-Higashi syndrome: brain MRI and MR spectroscopy manifestations

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An Erratum to this article was published on 30 April 2015

Abstract

Chédiak-Higashi syndrome is a rare inherited metabolic disorder characterized by partial oculocutaneous albinism, immunodeficiency, and neurological dysfunction. We present the brain magnetic resonance imaging (MRI) and MR spectroscopy (MRS) findings obtained during the accelerated phase of the disorder in an 8-year-old. The brain MRI manifestations at recurrences 15 months and 24 months later are reported as well.

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Conflicts of interest

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Authors and Affiliations

  1. Neuroradiology Department, Roger Salengro Hospital, CHRU, Lille, France

    Valentina Lolli, Gustavo Soto Ares & Jean-Pierre Pruvo

  2. Pediatric Hematology and Oncology Department, Jeanne de Flandre Hospital, Lille, France

    Wadih Abou Chahla

  3. Radiology Department – Pediatric Neuroradiology Section, University Hospital Saint-Pierre, Brussels, Belgium

    Patrice Jissendi-Tchofo

Authors
  1. Valentina Lolli
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  2. Gustavo Soto Ares
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  3. Jean-Pierre Pruvo
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  4. Wadih Abou Chahla
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  5. Patrice Jissendi-Tchofo
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Corresponding author

Correspondence to Valentina Lolli.

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Lolli, V., Soto Ares, G., Pruvo, JP. et al. Chédiak-Higashi syndrome: brain MRI and MR spectroscopy manifestations. Pediatr Radiol 45, 1253–1257 (2015). https://doi.org/10.1007/s00247-014-3256-x

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  • DOI: https://doi.org/10.1007/s00247-014-3256-x

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