Skip to main content
Log in

Outcomes of Infant Supraventricular Tachycardia Management Without Medication

  • Research
  • Published:
Pediatric Cardiology Aims and scope Submit manuscript

Abstract

Most infants presenting with supraventricular tachycardia (SVT) are treated with an antiarrhythmic, primarily to prevent unrecognized future episodes that could lead to tachycardia-induced cardiomyopathy. A common practice at our institution is to not treat after the first presentation of infant SVT and instead educate parents on heart rate monitoring and reasons to present to care. The goal of this study was to evaluate the outcomes of non-pharmacologic treatment of infant SVT at first presentation and compare to outcomes of infants treated with an antiarrhythmic. This was a retrospective single center study of all infants presenting with a first episode of SVT from 2014 to 2021. Excluded were patients with a non-reentry type tachyarrhythmia, atrial flutter, long-RP tachycardia, congenital heart disease, or abnormal ventricular function. Sixty-four infants were included in the study. Thirty-six were managed without an antiarrhythmic. SVT recurred in 28% of the non-treatment group vs 50% in those treated with antiarrhythmics, p = 0.12. Of the patients admitted to the hospital, those in the non-treatment group had a shorter length of stay, 1(IQR 1–1) vs 3(IQR 2–4) days, p < 0.01. Non-treated patients were less likely to present to the emergency department for recurrent SVT, 6% vs 32%, p < 0.01. Neither group had a patient develop tachycardia-induced cardiomyopathy. For infants with structurally and functionally normal hearts, non-treatment combined with parental education after the first episode of SVT does not lead to worse outcomes. This approach avoids the burden of medication administration in an infant and may have the added benefit of empowering parents to feel comfortable managing clinically insignificant tachycardia at home.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Abbreviations

SVT:

Supraventricular tachycardia

References

  1. Turner CJ, Wren C (2013) The epidemiology of arrhythmia in infants: a population-based study. J Paediatr Child Health 49(4):278–281. https://doi.org/10.1111/jpc.12155

    Article  PubMed  Google Scholar 

  2. Wu MH, Chen HC, Kao FY, Huang SK (2016) Postnatal cumulative incidence of supraventricular tachycardia in a general pediatric population: a national birth cohort database study. Heart Rhythm 13(10):2070–2075

    Article  PubMed  Google Scholar 

  3. Garson A Jr, Gillette PC, McNamara DG (1981) Supraventricular tachycardia in children: clinical features, response to treatment, and long-term follow-up in 217 patients. J Pediatr 98(6):875–882. https://doi.org/10.1016/s0022-3476(81)80578-1

    Article  PubMed  Google Scholar 

  4. Ko JK, Deal BJ, Strasburger JF, Benson DW Jr (1992) Supraventricular tachycardia mechanisms and their age distribution in pediatric patients. Am J Cardiol 69(12):1028–1032. https://doi.org/10.1016/0002-9149(92)90858-v

    Article  CAS  PubMed  Google Scholar 

  5. Wong KK, Potts JE, Etheridge SP, Sanatani S (2006) Medications used to manage supraventricular tachycardia in the infant a North American survey. Pediatr Cardiol 27(2):199–203. https://doi.org/10.1007/s00246-005-1126-x

    Article  CAS  PubMed  Google Scholar 

  6. Guerrier K, Shamszad P, Czosek RJ, Spar DS, Knilans TK, Anderson JB (2016) Variation in antiarrhythmic management of infants hospitalized with supraventricular tachycardia: a multi-institutional analysis. Pediatr Cardiol 37(5):946–952. https://doi.org/10.1007/s00246-016-1375-x

    Article  PubMed  Google Scholar 

  7. Mecklin M, Linnanmäki A, Hiippala A et al (2023) Multicenter cohort study on duration of antiarrhythmic medication for supraventricular tachycardia in infants. Eur J Pediatr 182(3):1089–1097. https://doi.org/10.1007/s00431-022-04757-5

    Article  CAS  PubMed  Google Scholar 

  8. Salerno JC, Garrison MM, Larison C, Seslar SP (2011) Case fatality in children with supraventricular tachycardia in the United States. Pacing Clin Electrophysiol 34(7):832–836. https://doi.org/10.1111/j.1540-8159.2011.03073.x

    Article  PubMed  Google Scholar 

  9. Moore JP, Patel PA, Shannon KM et al (2014) Predictors of myocardial recovery in pediatric tachycardia-induced cardiomyopathy. Heart Rhythm 11(7):1163–1169. https://doi.org/10.1016/j.hrthm.2014.04.023

    Article  PubMed  Google Scholar 

  10. Philips K, Zhou R, Lee DS et al (2019) Caregiver medication management and understanding after pediatric hospital discharge. Hosp Pediatr 9(11):844–850. https://doi.org/10.1542/hpeds.2019-0036

    Article  PubMed  PubMed Central  Google Scholar 

  11. Murray KA, Belanger A, Devine LT, Lane A, Condren ME (2017) Emergency department discharge prescription errors in an academic medical center. Proc (Bayl Univ Med Cent) 30(2):143–146. https://doi.org/10.1080/08998280.2017.11929562

    Article  PubMed  Google Scholar 

  12. Hasan RA, Zureikat GY, Nolan BM, Matisoff DN (1992) Postprandial hypoglycemia in an infant associated with propranolol. Pediatr Emerg Care 8(3):146–147. https://doi.org/10.1097/00006565-199206000-00009

    Article  CAS  PubMed  Google Scholar 

  13. Moore JA, Stephens SB, Kertesz NJ et al (2022) Clinical predictors of recurrent supraventricular tachycardia in infancy. J Am Coll Cardiol 80(12):1159–1172. https://doi.org/10.1016/j.jacc.2022.06.038

    Article  PubMed  Google Scholar 

  14. Sanatani S, Potts JE, Reed JH et al (2012) The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants. Circ Arrhythm Electrophysiol 5(5):984–991. https://doi.org/10.1161/CIRCEP.112.972620

    Article  CAS  PubMed  Google Scholar 

  15. Bruder D, Weber R, Gass M, Balmer C, Cavigelli-Brunner A (2022) Antiarrhythmic medication in neonates and infants with supraventricular tachycardia. Pediatr Cardiol 43(6):1311–1318. https://doi.org/10.1007/s00246-022-02853-9

    Article  PubMed  PubMed Central  Google Scholar 

  16. Bücking C, Michaelis A, Markel F et al (2022) Evaluation of clinical course and maintenance drug treatment of supraventricular tachycardia in children during the first years of life. A cohort study from Eastern Germany. Pediatr Cardiol 43(2):332–343. https://doi.org/10.1007/s00246-021-02724-9

    Article  PubMed  Google Scholar 

  17. Bozkurt B, Colvin M, Cook J et al (2016) Current diagnostic and treatment strategies for specific dilated cardiomyopathies: a scientific statement from the american heart association. Circulation 134(23):e579–e646. https://doi.org/10.1161/CIR.0000000000000455

    Article  PubMed  Google Scholar 

  18. Gilljam T, Jaeggi E, Gow RM (2008) Neonatal supraventricular tachycardia: outcomes over a 27-year period at a single institution. Acta Paediatr 97(8):1035–1039. https://doi.org/10.1111/j.1651-2227.2008.00823.x

    Article  PubMed  Google Scholar 

  19. Vari D, Kurek N, Zang H, Anderson JB, Spar DS, Czosek RJ (2022) Outcomes in infants with supraventricular tachycardia: risk factors for readmission recurrence and alblation. Pediatr Cardiol. https://doi.org/10.1007/s00246-022-03035-3

    Article  PubMed  Google Scholar 

  20. Anjewierden S, Humpherys J, LaPage MJ, Asaki SY, Aziz PF (2021) Detection of tachyarrhythmias in a large cohort of infants using direct-to-consumer heart rate monitoring. J Pediatr 232:147-153.e1. https://doi.org/10.1016/j.jpeds.2020.12.080

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

None.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Author information

Authors and Affiliations

Authors

Contributions

All authors participated in the concept and design of the study, interpretation of data, and drafting or revising of the manuscript. All authors also approved the final manuscript as submitted and agree to be accountable for all aspects of the work.

Corresponding author

Correspondence to Anthony G. Pompa.

Ethics declarations

Conflict of interest

The authors have no conflicts of interest to disclose.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pompa, A.G., LaPage, M.J. Outcomes of Infant Supraventricular Tachycardia Management Without Medication. Pediatr Cardiol (2023). https://doi.org/10.1007/s00246-023-03263-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00246-023-03263-1

Keywords

Navigation