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New technique: the use of the THRIVE sequence in the follow-up of patients who received endovascular intracranial aneurysm treatment

  • Interventional Neuroradiology
  • Published:
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Abstract

Purpose

To determine the diagnostic accuracy of 3D time of flight MR angiography (TOF-MRA), contrast enhanced MR angiography (CE-MRA), and T1-weighted high-resolution isotropic volume examination (THRIVE) at 3 T for the evaluation of intracranial aneurysm occlusion after endovascular treatment and to evaluate the usability of the THRIVE sequence in endovascular treatment follow-up.

Methods

In 3 T MR follow-up examinations of 66 aneurysms in 50 patients treated endovascularly, 3D TOF-MRA (index test), THRIVE (index test), and CE-MRA (reference standard) examinations were performed in a retrospective consecutive case series. Source images were classified as class 1, class 2, and class 3 according to the Raymond criteria using MIP (maximum intensity projection) techniques. The compatibility between sequences was evaluated with the Kappa test. The sensitivity and specificity were also calculated.

Results

In the evaluation of THRIVE and CE-MRA sequences, compatibility was determined in 61 cases in total, with an overall fit of 61/66 (92.42%). A statistically significant correlation was found between THRIVE and CE-MRA (p < 0.001, κ = 0.800). In the evaluation of TOF and CE-MRA sequences, compatibility was determined in 54 cases in total, and the overall fit was 54/66 (81.8%). A statistically significant agreement was found between TOF and CE-MRA (p < 0.001, κ = 0.502). Assuming that CE-MRA is a reference standard, the sensitivity and specificity of the TOF sequence were 44.4% and 97.9%, respectively, and the sensitivity and specificity of the THRIVE sequence were 77.8% and 97.9%, respectively.

Conclusion

The THRIVE sequence can be used as a noncontrast method for monitoring endovascularly treated intracranial aneurysms.

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Availability of data and material

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Authors and Affiliations

  1. Department of Radiology, Patnos State Hospital, 04500, Patnos, Ağrı, Turkey

    Emre Mırçık

  2. Department of Radiology, Bursa Uludag University Faculty of Medicine, 16059, Nilüfer, Bursa, Turkey

    Bahattin Hakyemez

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  1. Emre Mırçık
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Correspondence to Bahattin Hakyemez.

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Mırçık, E., Hakyemez, B. New technique: the use of the THRIVE sequence in the follow-up of patients who received endovascular intracranial aneurysm treatment. Neuroradiology 63, 399–407 (2021). https://doi.org/10.1007/s00234-020-02527-4

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  • DOI: https://doi.org/10.1007/s00234-020-02527-4

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