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A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications

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Abstract

Encapsulation of bioactive compound has some encountered issues associated particularly to their mode of fabrication, design, and biodegradability. For these reasons, selecting appropriate coating materials like hydroxyl cellulose has several advantages such as modification of moisture, crystal growth, and viscosity. In addition, starches, maltodextrins, whey proteins, chitosan, zein/pectin, and alginates are considered an important coating materials used during microencapsulation processing steps. Thus, the variability in the hydrophilicity, lipophilicity and chargeability levels of those coating materials along with the encapsulation is considered among the molecular aspects in forming genius emulsion vesicles, microgels, solid lipid nanoparticles, liposomes, or core shell nanoparticles. These encapsulation designs are capable in promoting variable physicochemical and therapeutic features such as intra-atomic dimensions, dispersed volumes, release kinetics, and stability levels. Under these desired structural and molecular parameters, in addition to proper optimization of processing conditions, perfect microcarriers and microcapsules could be achieved. Moreover, appropriate control of copolymerization and crystallization of the coating materials with some antagonistic pharmaceutical drugs needs special emphasize. In general, this manuscript reviews various important aspects of structured materials used along with their production and potential uses for enhancing targeted delivery and release of therapeutic foods.

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Acknowledgements

The authors acknowledge the INATAA Mentouri Frere University of Algeria, Universiti Putra Malaysia UPM and Sargodha University of Pakistan for microencapsulation design and application.

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Authors and Affiliations

  1. Institute de La Nutrition, de l’Alimentation Et Des Technologies Agroalimetaires INATAA, Université Des Frères Mentouri Constantine 1, Route de Ain El Bey-Constantine, Constantine, Algeria

    Sami Saadi

  2. Laboratoire de Génie Agro-Alimentaire (GeniAAl), INATAA, Université Frères Mentouri Constantine 1 UFC1, Route de Ain El Bey-Constantine, Constantine, Algeria

    Sami Saadi

  3. Department of Biology of Organisms, Faculty of Natural and Life Sciences, University of Batna 2, 05000, Batna, Algeria

    Nor Elhouda Nacer

  4. Higher National School of Forests, 40000, Khenchela, Algeria

    Hichem Chenaker

  5. Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia

    Abdul Azis Ariffin, Hasanah Mohd Ghazali, Nazamid Saari, Farooq Anwar & Azizah Abdul Hamid

  6. Department of Microbiology and Biotechnology, Federal University Dutse, Dutse, Nigeria

    Abdulkarim Sabo Mohammed

  7. Institute of Chemistry, University of Sargodha, Sargodha, 40100, Pakistan

    Farooq Anwar

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  1. Sami Saadi
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  2. Nor Elhouda Nacer
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Correspondence to Sami Saadi.

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Saadi, S., Nacer, N.E., Chenaker, H. et al. A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications. Eur Food Res Technol 249, 3123–3139 (2023). https://doi.org/10.1007/s00217-023-04354-2

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