Abstract
Rationale
Relative reinforcing efficacy (RRE) is a core feature of behavioral economic theories of addiction. A measure of RRE in smokers is the cigarette purchase task (CPT). Only one previous study has assessed whether CPT indices predict treatment outcomes among smokers with substance use disorders (SUDs) who were not motivated to quit smoking, limiting the generalizability of the results.
Objectives
This study was aimed at exploring demand indices as predictors of smoking abstinence among participants receiving a cognitive behavioral treatment (CBT) combined with contingency management (CM) versus CBT alone. It also sought to validate the CPT as a measure of RRE.
Methods
Participants were 159 (62.3 % women) smokers aged 44.8 (SD 12.6) years randomized to CBT alone or combined with CM. They smoked an average of 21.1 (SD 8.5) cigarettes per day, and their mean score on the Fagerström Test for Nicotine Dependence (FTND) was 5.5 (SD 1.9). Demand indices were generated from a hypothetical CPT assessed at baseline.
Results
Smoking levels were high (≥20 cigarettes) at prices of up to €0.10 per cigarette. Elasticity was the only index that predicted smoking abstinence at the end of treatment, but only in the CBT + CM condition. The variance explained by elasticity was 6.8 % in the independent model and 4.6 % in the covariate model. Cigarette demand indices and smoking-related measures were significantly associated.
Conclusion
This is the first research showing that CPT is a valid measure of CM outcome among treatment-seeking smokers. This study also provides evidence of convergent validity for the CPT.
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References
Acker J, MacKillop J (2013) Behavioral economic analysis of cue-elicited craving for tobacco: a virtual reality study. Nic Tob Res 15:1409–1416. doi:10.1093/ntr/nts341
American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders (4th ed., text revision), Washington
Amlung MT, Acker J, Stojek MK, Murphy JG, MacKillop J (2012) Is talk “cheap”? An initial investigation of the equivalence of alcohol purchase task performance for hypothetical and actual rewards. Alcohol Clin Exp Res 36:716–724. doi:10.1111/j.1530-0277.2011.01656.x
Aston ER, Metrik J, MacKillop J (2015) Further validation of a marijuana purchase task. Drug Alcohol Depend 152:32–38. doi:10.1016/j.drugalcdep.2015.04.025
Bickel WK, Madden GJ (1999) A comparison of measures of relative reinforcing efficacy and behavioral economics: cigarettes and money in smokers. Behav Pharmacol 10:627–637. doi:10.1097/00008877-199911000-00009
Bickel WK, Madden GJ, DeGrandpre RJ (1997) Modeling the effects of combined behavioral and pharmacological treatment on cigarette smoking: behavioral-economic analyses. Exp Clin Psychopharmacol 5:334–343. doi:10.1037/1064-1297.5.4.334
Bickel WK, Marsch LA, Carroll ME (2000) Deconstructing relative reinforcing efficacy and situating the measures of pharmacological reinforcement with behavioral economics: a theoretical proposal. Psychopharmacology 153:44–56. doi:10.1007/s002130000589
Bidwell LC, MacKillop J, Murphy JG, Tidey JW, Colby SM (2012) Latent factor structure of a behavioral economic cigarette demand curve in adolescent smokers. Addict Behav 37:1257–1263. doi:10.1016/j.addbeh.2012.06.009
Bruner NR, Johnson MW (2014) Demand curves for hypothetical cocaine in cocaine-dependent individuals. Psychopharmacology 231:889–897. doi:10.1007/s00213-013-3312-5
Chase HW, MacKillop J, Hogarth L (2013) Isolating behavioural economic indices of demand in relation to nicotine dependence. Psychopharmacology 226:371–380. doi:10.1007/s00213-012-2911-x
Cohen J (1988) Statistical power analysis for the behavioral sciences. Erlbaum, Hillsday
Few LR, Acker J, Murphy C, MacKillop J (2012) Temporal stability of a cigarette purchase task. Nicotine Tob Res 14:761–765. doi:10.1093/ntr/ntr222
Griffiths RR, Brady JV, Bradford LD (1979) Predicting the abuse liability of drugs and animal drug self-administration procedures: psychomotor stimulants and hallucinogens. In: Thompson T, Dews PB (eds) Advances in behavioral pharmacology. Academic, New York, pp 163–208
Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO (1991) The Fagerstrom test for nicotine dependence: a revision of the Fagerstrom tolerance questionnaire. Br Journal Addict 86:1119–1127. doi:10.1111/j.1360-0443.1991.tb01879.x
Higgins ST, Bickel WK, Hughes JR (1994) Influence of an alternative reinforcer on human cocaine self-administration. Life Sci 55:179–187. doi:10.1016/0024-3205(94)00878-7
Higgins ST, Heil SH, Lussier JP (2004) Clinical implications of reinforcement as a determinant of substance use disorders. Annu Rev Psychol 55:431–461. doi:10.1146/annurev.psych.55.090902.142033
Hursh SR, Silberberg A (2008) Economic demand and essential value. Psychol Rev 115:186–198. doi:10.1037/0033-295x115.1.186
Jacobs EA, Bickel WK (1999) Modeling drug consumption in the clinic using simulation procedures: demand for heroin and cigarettes in opioid-dependent outpatients. Exp Clin Psychopharmacol 7:412–426
Johnson MW, Bickel WK (2006) Replacing relative reinforcing efficacy with behavioral economic demand curves. J Exp Anal Behav 85:73–93. doi:10.1901/jeab.2006.102-04
López-Núñez C, Loredo-Martínez V, Weidberg S, Pericot-Valverde I, Secades - Villa R (2015) Voucher-based contingency management and in-treatment behaviors in smoking cessation treatment. Int J Clin Hlth Psyc. doi:10.1016/j.ijchp.2015.05.003
Lussier JP, Heil SH, Mongeon JA, Badger GJ, Higgins ST (2006) A meta-analysis of voucher-based reinforcement therapy for substance use disorders. Addiction 101:192–203. doi:10.1111/j.1360-0443.2006.01311.x
MacKillop J, Murphy JG (2007) A behavioral economic measure of demand for alcohol predicts brief intervention outcomes. Drug Alcohol Depend 89:227–233. doi:10.1016/j.drugalcdep.2007.01.002
MacKillop J, Tidey JW (2011) Cigarette demand and delayed reward discounting in nicotine-dependent individuals with schizophrenia and controls: an initial study. Psychopharmacology 216:91–99. doi:10.1007/s00213-011-2185-8
MacKillop J, Murphy JG, Ray LA, Eisenberg DTA, Lisman SA, Lum JK, Wilson DS (2008) Further validation of a cigarette purchase task for assessing the relative reinforcing efficacy of nicotine in college smokers. Exp Clin Psychopharmacol 16:57–65. doi:10.1037/1064-1297.16.1.57
MacKillop J, Murphy JG, Tidey JW, Kahler CW, Ray LA, Bickel WK (2009) Latent structure of facets of alcohol reinforcement from a behavioral economic demand curve. Psychopharmacology 203:33–40. doi:10.1007/s00213-008-1367-5
MacKillop J, Miranda R, Monti PM, Ray LA, Murphy JG, Rohsenow DJ, McGeary JE, Swift RM, Tidey JW, Gwaltney CJ (2010) Alcohol demand, delayed reward discounting, and craving in relation to drinking and alcohol use disorders. J Abnorm Psychol 119:106–114. doi:10.1037/a0017513
Mackillop J, Murphy CM, Martin RA, Stojek M, Tidey JW, Colby SM, Rohsenow DJ (2015) Predictive validity of a cigarette purchase task in a randomized controlled trial of contingent vouchers for smoking in individuals with substance use disorders. Nicotine Tob Res. doi:10.1093/ntr/ntv233
McClure EA, Vandrey RG, Johnson MW, Stitzer ML (2013) Effects of varenicline on abstinence and smoking reward following a programmed lapse. Nicotine Tob Res 15:139–148. doi:10.1093/ntr/nts101
Murphy JG, MacKillop J (2006) Relative reinforcing efficacy of alcohol among college student drinkers. Exp Clin Psychopharmacol 14:219–227. doi:10.1037/1064-1397.14.2.219
Murphy JG, MacKillop J, Tidey JW, Brazil LA, Colby SM (2011) Validity of a demand curve measure of nicotine reinforcement with adolescent smokers. Drug Alcohol Depend 113:207–214. doi:10.1016/j.drugalcdep.2010.08.004
Roll JM, Higgins ST (2000) A within-subject comparison of three different schedules of reinforcement of drug abstinence using cigarette smoking as exemplar. Drug Alcohol Depend 58:103–109. doi:10.1016/s0376-8716(99)00073-3
Shiffman S, Waters AJ, Hickcox M (2004) The nicotine dependence syndrome scale: a multidimensional measure of nicotine dependence. Nicotine Tob Res 6:327–348. doi:10.1080/1462220042000202481
Tabachnick BG, Fidell LS (2006) Using multivariate statistics, 5th edn. Allyn & Bacon, Inc, Needham Heights
Acknowledgments
We acknowledge the valuable assistance of Carla López-Núñez, Víctor Martínez-Loredo, and Alba González-Roz with participant recruitment and data collection.
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The present study was supported by a grant from the Council for Economy and Work (GRUPIN14-047) awarded to the Addictive Behaviors Research Group and by a predoctoral grant from the Spanish Ministry of Economy and Competitiveness (MINECO) (Ref. BES-2012-053988). Both funding sources played no role in the study design, data collection, analysis, or interpretation of the results.
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The authors declare that there is no conflict of interest.
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Secades-Villa, R., Pericot-Valverde, I. & Weidberg, S. Relative reinforcing efficacy of cigarettes as a predictor of smoking abstinence among treatment-seeking smokers. Psychopharmacology 233, 3103–3112 (2016). https://doi.org/10.1007/s00213-016-4350-6
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DOI: https://doi.org/10.1007/s00213-016-4350-6