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Nuts and Their Potential Role in Alzheimer’s Disease

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Nutraceuticals for Alzheimer's Disease: A Promising Therapeutic Approach

Part of the book series: Nutritional Neurosciences ((NN))

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Abstract

The rising incidence of Alzheimer’s disease (AD), a challenging neurological disorder, is a practically global issue. To find potential treatments for the condition, research is being done on natural products. The potential therapeutic properties of tree nuts have been analyzed in many research articles and traditional medicinal systems like Persian Medicine because of their properties to protect the brain. The purpose of this chapter is to emphasize the advantages of consuming nuts as dietary supplements and natural therapies for AD patients by providing a pharmacological evaluation of their bioactive components. The macronutrients, micronutrients, and phytochemicals found in almonds, hazelnuts, and walnuts have an effect on several pathways involved in the pathogenesis of AD, such as amyloidogenesis, tau phosphorylation, oxidative stress, cholinergic pathways, and some nontarget mechanisms, such as effects on neurogenesis and cholesterol-lowering and anti-inflammatory properties. Especially in the case of hazelnut, it reverses brain atrophy. Along with almonds, walnuts, and hazelnuts, other nuts like pistachio, pine nuts, peanuts, areca nuts, kola nuts, and pecan nuts also have the potential to ameliorate Alzheimer’s disease by their bioactive components. Beyond the molecular effects associated with the phytochemicals, the utilization of these tree nuts as valuable nutrients for the prevention or perhaps management of AD may be more thoroughly investigated in scientific investigations.

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Authors and Affiliations

  1. Department of Molecular Microbiology, School of Biotechnology, Madurai Kamaraj University, Madurai, Tamil Nadu, India

    Ganesh Vaishnavi

  2. Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Chidambaram, Tamil Nadu, India

    Arokiasamy Justin Thenmozhi

  3. Department of Biochemistry, School of Biological Sciences, Madurai Kamaraj University, Madurai, Tamil Nadu, India

    Arokiasamy Justin Thenmozhi

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  1. Ganesh Vaishnavi
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  2. Arokiasamy Justin Thenmozhi
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Editors and Affiliations

  1. Department of Biochemistry, Madurai Kamaraj University, Madurai, Tamil Nadu, India

    Arokiyasamy Justin Thenmozhi

  2. Department of Biochemistry and Biotechnology, Annamalai University, Chidambaram, Tamil Nadu, India

    Thamilarasan Manivasagam

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Vaishnavi, G., Justin Thenmozhi, A. (2023). Nuts and Their Potential Role in Alzheimer’s Disease. In: Thenmozhi, A.J., Manivasagam, T. (eds) Nutraceuticals for Alzheimer's Disease: A Promising Therapeutic Approach. Nutritional Neurosciences. Springer, Singapore. https://doi.org/10.1007/978-981-99-0677-2_9

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  • DOI: https://doi.org/10.1007/978-981-99-0677-2_9

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  • Online ISBN: 978-981-99-0677-2

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