Skip to main content

Development of an Automated Algorithm to Quantify Optic Nerve Diameter Using Ultrasound Measures: Implications for Optic Neuropathies

  • Conference paper
  • First Online:
Computer Vision and Machine Intelligence

Part of the book series: Lecture Notes in Networks and Systems ((LNNS,volume 586))

  • 505 Accesses

Abstract

The paper presents a novel computational and image processing algorithm for automatic measurement of optic nerve diameter (OND) from B-scan ultrasound images acquired in a traumatic cohort. The OND is an important diagnostic parameter for the detection and therapeutic planning of several diseases and trauma cases. The automated measurement of OND may provide reliable information for predicting intracranial pressure (ICP) in traumatic patients. In the proposed method, the automatic measurement of the OND involves pre-processing an ultrasound image, followed by retinal globe detection, optic nerve localization, optic nerve tip detection and measurement of OND. The proposed algorithm measures the OND in the perpendicular direction to the optic nerve axis, considering the orientation of the optic nerve in an automated framework. The developed algorithm automatically calculates the OND. The study includes Twenty-four traumatic individuals with optic nerve pathologies whose B-scan ultrasound images of the optic nerve were manually obtained in the axial plane. The accuracy of the automatic measurement has been quantified by comparing it with manually measured OND by medical experts. A low Percent Root Mean Square Difference (PRD) value of 14.92% between automated and manually measured OND is found as an accuracy measure for the automatic measurement of OND. The proposed algorithm automatically and accurately determines the optic nerve diameter from an eye ultrasound image.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. del Saz-Saucedo, P., et al.: Sonographic assessment of the optic nerve sheath diameter in the diagnosis of idiopathic intracranial hypertension. J. Neurol. Sci. 361, 122–127 (2016)

    Google Scholar 

  2. De La Hoz Polo, M., et al.: Ocular ultrasonography focused on the posterior eye segment: what radiologists should know. Insights Imaging 7(3), 351–364 (2016)

    Google Scholar 

  3. Sahoo, ,S.S., Agrawal, D.: Correlation of optic nerve sheath diameter with intracranial pressure monitoring in patients with severe traumatic brain injury. Indian J. Neurotrauma 10, 9–12 (2013)

    Google Scholar 

  4. Li, J., Wan, C.: Non-invasive detection of intracranial pressure related to the optic nerve. Quant. Imaging Med. Surg. 11(6), 2823–2836 (2021). https://doi.org/10.21037/qims-20-1188

    Article  Google Scholar 

  5. Kishk, N.A., et al.: Optic nerve sonographic examination to predict raised intracranial pressure in idiopathic intracranial hypertension: the cut-off points. Neuroradiology J. 31(5), 490–495 (2018)

    Google Scholar 

  6. Nguyen, B.N., et al.: Ultra-high field magnetic resonance imaging of the retrobulbar optic nerve, subarachnoid space, and optic nerve sheath in emmetropic and myopic eyes. Transl. Vis. Sci. Technol. 10(2), 8 (2021). https://doi.org/10.1167/tvst.10.2.8

  7. Kimberly, H.H., Noble, V.E.: Using MRI of the optic nerve sheath to detect elevated intracranial pressure. Crit Care 12, 181 (2008)

    Article  Google Scholar 

  8. Kalantari, H., Jaiswal, R., Bruck, I., et al.: Correlation of optic nerve sheet diameter measurements by computed tomography and magnetic resonance imaging. Am. J. Emerg. Med. 31, 1595–1597 (2013)

    Article  Google Scholar 

  9. Gupta, S., Pachisia, A.: Ultrasound-measured optic nerve sheath diameter correlates well with cerebrospinal fluid pressure. Neurol. India 67(3), 772 (2019)

    Google Scholar 

  10. Chen, H.,Ding, G.S., Zhao, Y.C., Yu, R.G., Zho, J.X.: Ultrasound measurement of optic nerve diameter and optic nerve sheath diameter in healthy Chinese adults. BMC Neurology 15, 106 (2015)

    Google Scholar 

  11. Lagreze, W.A., Lazzaro, A., Weigel, M., Hansen, H.-C., Hennig, J., Bley, T.A.: Morphometry of the retrobulbar human optic nerve: comparison between conventional sonography and ultrafast magnetic resonance sequences. Invest. Ophthalmol. Vis. Sci. 48(5), 1913–1917 (2007)

    Article  Google Scholar 

  12. Kilker, B.A., Holst, J.M., Hoffmann, B.: Bedside ocular ultrasound in the emergency department. Eur J Emerg Med. 21(4), 246–253 (2014)

    Article  Google Scholar 

  13. Mateo, J.L., Fernández-Caballero, A.: Finding out general tendencies in speckle noise reduction in ultrasound images. Expert Syst. Appl. 36(4), 7786–7797 (2009)

    Article  Google Scholar 

  14. Michailovich, O.V., Tannenbaum, A.: Despeckling of medical ultrasound images. IEEE Trans. Ultrason. Ferroelectr. Freq. Control 53(1), 64–78 (2006)

    Google Scholar 

  15. Burckhardt, C.B.: Speckle in ultrasound B-mode scans. IEEE Trans. Sonics Ultrason. 25(1), 1–6 (1978)

    Article  Google Scholar 

  16. Tasnim, T., Shuvo, M.M., Hasan, S.: Study of speckle noise reduction from ultrasound B-mode images using different filtering techniques. In 2017 4th International Conference on Advances in Electrical Engineering (ICAEE), pp. 229–234. IEEE (2017)

    Google Scholar 

  17. Joel, T., Sivakumar, R.: An extensive review on Despeckling of medical ultrasound images using various transformation techniques. Appl. Acoust. 138, 18–27 (2018)

    Article  Google Scholar 

  18. Geeraerts, T., et al.: Use of T2-weighted magnetic resonance imaging of the optic nerve sheath to detect raised intracranial pressure. Critical Care (London, England) 12(5), R114 (2008). https://doi.org/10.1186/cc7006

  19. Geeraerts, T., Merceron, S., Benhamou, D., Vigué, B., Duranteau, J.: Non-invasive assessment of intracranial pressure using ocular sonography in neurocritical care patients. Intensive Care Med. 34, 2062–2067 (2008). https://doi.org/10.1007/s00134-008-1149-x

    Article  Google Scholar 

  20. Lochner, P., Coppo, L., Cantello, R., et al.: Intra- and interobserver reliability of transorbital sonographic assessment of the optic nerve sheath diameter and optic nerve diameter in healthy adults. J. Ultrasound 19, 41–45 (2016). https://doi.org/10.1007/s40477-014-0144-z

    Article  Google Scholar 

  21. Pansell, J., Bell, M., Rudberg, P., Friman, O., Cooray, C.: Optic nerve sheath diameter measurement by ultrasound: Evaluation of a standardized protocol. J. Neuroimaging 32(1), 104–110 (2022)

    Article  Google Scholar 

  22. Youm, J.Y., Lee, J.H., Park, H.S.: Comparison of transorbital ultrasound measurements to predict intracranial pressure in brain-injured patients requiring external ventricular drainage. J. Neurosurg. 23, 1–7 (2021)

    Google Scholar 

  23. Nag, D.S., Sahu, S., Swain, A., Kant, S.: Intracranial pressure monitoring: gold standard and recent innovations. World J. Clin. Cases 7, 1535–1553 (2019)

    Article  Google Scholar 

  24. Du, J., Deng, Y., Li, H., Qiao, S., Yu, M., Xu, Q., et al.: Ratio of optic nerve sheath diameter to eyeball transverse diameter by ultrasound can predict intracranial hypertension in traumatic brain injury patients: a prospective study. Neurocrit. Care 32, 478–485 (2020)

    Article  Google Scholar 

  25. Titlic, M., Erceg, I., Kovacevic, T., et al.: The correlation of changes of the optic nerve diameter in the acute retrobulbar neuritis with the brain changes in multiple sclerosis. Coll. Antropol. 29, 633–636 (2005)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Maninder Singh .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Gupta, V., Singh, M., Gupta, R., Kumar, B., Agarwal, D. (2023). Development of an Automated Algorithm to Quantify Optic Nerve Diameter Using Ultrasound Measures: Implications for Optic Neuropathies. In: Tistarelli, M., Dubey, S.R., Singh, S.K., Jiang, X. (eds) Computer Vision and Machine Intelligence. Lecture Notes in Networks and Systems, vol 586. Springer, Singapore. https://doi.org/10.1007/978-981-19-7867-8_23

Download citation

Publish with us

Policies and ethics