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Aquaporins in Eye

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Aquaporins

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1398))

Abstract

The major part of the eye consists of water. Continuous movement of water and ions between the ocular compartments and to the systemic circulation is pivotal for many physiological functions in the eye. The movement of water facilitates removal of the many metabolic products of corneal-, ciliary body-, lens-, and retinal metabolism, while maintaining transparency in the optical compartments. Transport across the corneal epithelium and endothelium maintains the corneal transparency. Also, aqueous humor is continuously secreted by the epithelia of the ciliary body and maintains the intraocular pressure. In the retina, water is transported into the vitreous body and across the retinal pigment epithelium to regulate the extracellular environment and the hydration of the retina. Aquaporins are a major contributor in the water transport throughout the eye.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, Rigshospitalet – Glostrup, University of Copenhagen, Copenhagen, Denmark

    Thuy Linh Tran, Steffen Hamann & Steffen Heegaard

Authors
  1. Thuy Linh Tran
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  2. Steffen Hamann
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  3. Steffen Heegaard
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Editors and Affiliations

  1. School of Basic Medical Sciences, Peking University, Beijing, China

    Baoxue Yang

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© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Tran, T.L., Hamann, S., Heegaard, S. (2023). Aquaporins in Eye. In: Yang, B. (eds) Aquaporins. Advances in Experimental Medicine and Biology, vol 1398. Springer, Singapore. https://doi.org/10.1007/978-981-19-7415-1_14

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