Abstract
The dermal melanocytoses comprise nevus of Ota, nevus of Ito, Mongolian spot, acquired dermal melanocytosis, Hori’s nevus, and blue nevi, among others. Histologically, they are characterized by the presence of melanin-laden dendritic melanocytes among the collagen bundles. Delayed migration from the neural crest to the epidermis may cause a hamartomatous distribution of melanocytes in the dermis. The Tyndall effect of melanin on these dermal melanocytes finally leads to bluish discoloration of the lesion. While nevus of Ito and nevus of Ota persist into adulthood, Mongolian spots are most likely to regress spontaneously during childhood. Although the transformation of dermal melanocytoses to melanoma is possible, the possibility is exceedingly rare.
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Tan, C., Zhu, WY. (2023). Congenital and Acquired Dermal Hypermelanosis. In: Tan, C., Zhu, WY. (eds) Atlas of Pigmentary Skin Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-19-5634-8_15
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