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Fungal Hydrophobins

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Fungal Biopolymers and Biocomposites

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Abstract

Hydrophobins are cysteine-rich amphipathic proteins found throughout the fungal kingdom and play important functions in the fungal life cycle. They are known to be involved in the conidiogenesis and formation of appressorium in Magnapothe oryzae and Metarhizium anisopliae, the growth of microsclerotia in Verticillium dahlia, and the development of microconidia in Fusarium verticillioides. Hydrophobins are also involved in disseminating Cladosporium fulvum spores and the production of aerial hyphae in Schizophyllum commune. Moreover, fungal hydrophobins have been well studied at the biochemical and molecular levels. Their role in the life cycles of Agaricus bisporus, Aspergillus fumigatus, A. nidulans, Magnaporthe grisea, Neurospora crassa, Ophiostoma ulmi, Schizophyllum commune, Trichoderma harzianum, and T. reesei have also been studied. Furthermore, the amphipathic characteristics of fungal hydrophobins have been used to solubilize and deliver hydrophobic medicines, as well as for purification and immobilization of proteins, as a antimicrobial coats, in biosensor development, and also as emulsifying agents.

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Acknowledgement

The financial support from the Department of Biotechnology, New Delhi is gratefully acknowledged.

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Authors and Affiliations

  1. Nanobioscience, Agharkar Research Institute, Pune, Maharashtra, India

    Vandana Ghormade

  2. Research and Development Division, Greenvention Biotech Pvt. Ltd., Pune, Maharashtra, India

    S. G. Tupe & Mukund V. Deshpande

  3. Department of Biotechnology, Indian Institute of Technology-Bombay, Mumbai, India

    Ejaj Pathan

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  1. Vandana Ghormade
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  2. S. G. Tupe
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  4. Mukund V. Deshpande
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  1. Research and Development Division, Greenvention Biotech Pvt. Ltd., Pune, Maharashtra, India

    Sunil K. Deshmukh

  2. Research and Development Division, Greenvention Biotech Pvt. Ltd., Pune, Maharashtra, India

    Mukund V. Deshpande

  3. Department of Biosciences, Mangalore University, Mangalore, Karnataka, India

    Kandikere R. Sridhar

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Ghormade, V., Tupe, S.G., Pathan, E., Deshpande, M.V. (2022). Fungal Hydrophobins. In: Deshmukh, S.K., Deshpande, M.V., Sridhar, K.R. (eds) Fungal Biopolymers and Biocomposites. Springer, Singapore. https://doi.org/10.1007/978-981-19-1000-5_3

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