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Fish Lectins as Molecular Markers

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Aquatic Lectins

Abstract

Lectins are a collection of primordial carbohydrate-binding protein molecules with multiple functions. These proteins exist in fish and other animals which bind to cell surface and surface glycans. Sequence and expression analysis shows they actively binds and interacts with innate and adaptative immune responses of various disease-causing agents. Immense advancement have been developed for the current existence for recreation of lectins in numerous natural processes. In this current scenario, lectins are regarded as an invaluable tool for the study of sequencing interactions among various pathogens. They also display a range of biological functions together with the development of new drugs and disease diagnostic tools for the treatment of numerous diseases. The present chapter concentrates the precise purpose of lectins sequencing and their interactions towards therapeutic implements.

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Abbreviations

CD209:

Cluster of differentiation 209

CTLD:

C-type lectin domain

C-type:

Ca2+ dependent

DC:

Dendritic cell

DC-SIGN:

Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin

DNA:

Deoxyribonucleic acid

MHC:

Major histocompatibility complex

mRNA:

Messenger ribonucleic acid

OnBML:

B-type mannose-binding lectin

RNA:

Ribonucleic acid

zINTLs:

Intelectin

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Acknowledgements

The authors JJ and AS would like to thank and acknowledge the Ministry of Human Resource Development, Government of India and Alagappa University, Karaikudi, for providing financial support under RUSA 2.0 scheme for this study. The author S. Bhavaniramya acknowledges the financial assistantship provided by University Grants Commission (UGC Award letter. F.4-2/2006(BSR)/BL/20-21/0014 (89th List)/ Dated 14 September 2021) under Dr. D. S. Kothari, Post-Doctoral Fellowship at Alagappa University, Karaikudi.

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The authors declare no conflict of interest, regarding this chapter.

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Jeyavani, J., Sibiya, A., Bhavaniramya, S. (2022). Fish Lectins as Molecular Markers. In: Elumalai, P., Vaseeharan, B., Lakshmi, S. (eds) Aquatic Lectins. Springer, Singapore. https://doi.org/10.1007/978-981-19-0432-5_15

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