Abstract
Tissue engineering involves restoration of altered tissue architecture by transplantation of cells on supportive matrix formed by scaffolds and nanoscaffolds. The matrix fabrication provides 3D platform for suitable cellular interaction for performing biochemical functions. The matrix supports the cellular growth by cell adhesion, migration, proliferation, differentiation followed by colonization of cells onto it. The nanoscale fabrication of scaffolds resembles the structural features of extracellular matrix (ECM). The cells colonized on nanoscaffolds are biocompatible, immunocompatible, and biofunctional tissue inside the body, thus eliminating the chance of rejection. The cellular implantation using scaffolds on skin tissue may help to combat the drawbacks which are associated with the autologous grafting and allograft tissue transplantation. The nanoscaffolds play a potent role in combating the bone and cartilage defects. The scaffold formed by the combination of organic and inorganic particle showed improved biocompatibility and mechanical strength in bone tissue engineering
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Ghosh, N., Ray Banerjee, E. (2020). Nanoscaffolds in Tissue Engineering. In: Ray Banerjee, E. (eds) Nanomaterials and Biomedicine. Springer, Singapore. https://doi.org/10.1007/978-981-15-5274-8_4
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DOI: https://doi.org/10.1007/978-981-15-5274-8_4
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