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Cytogenetic Factors in Male Infertility

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Male Infertility: Understanding, Causes and Treatment

Abstract

Nearly 15% of the couples worldwide face the problem of infertility. A number of cytogenetic aberrations in the form of somatic chromosome aneuploidies, sperm aneuploidies, chromosomal translocations and inversions, etc. are known to contribute to male infertility. Couples with normal hormonal profile should be evaluated for possible cytogenetic abnormalities before proceeding to treatment. The identification of cytogenetic abnormality cannot only explain infertility but also guide treatment in the affected cases. This chapter summarizes the cytogenetic factors that increase the risk of male infertility. Towards the end, we have provided a glimpse of the contemporary techniques that have revolutionized the classical field of cytogenetics.

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Authors and Affiliations

  1. Department of Molecular and Human Genetics, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, India

    Vertika Singh & Kiran Singh

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  1. Vertika Singh
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  2. Kiran Singh
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Correspondence to Kiran Singh .

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  1. Endocrinology Division, Central Drug Research Institute, Lucknow, Uttar Pradesh, India

    RAJENDER SINGH

  2. Department of Molecular and Human Genetics, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, India

    Kiran Singh

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Singh, V., Singh, K. (2017). Cytogenetic Factors in Male Infertility. In: SINGH, R., Singh, K. (eds) Male Infertility: Understanding, Causes and Treatment. Springer, Singapore. https://doi.org/10.1007/978-981-10-4017-7_13

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