Abstract
The lower urinary tract is distinct from other visceral organs due to its reliance on neural input from the central nervous system. A complex network distributed across the parasympathetic, sympathetic and somatic neural pathways, and controlled by different centres at the level of the brain stem acts as a switching circuit to maintain the functions of the lower urinary tract (LUT)-to coordiate low pressure filling and periodic voluntary emptying. This chapter provides an overview of this neural network.
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References
de Groat WC. Anatomy of the central neural pathways controlling the lower urinary tract. Eur Urol. 1998;34(Suppl 1):2–5.
Espinosa-Medina I, Saha O, Boismoreal F, et al. The sacral autonomic outflow is sympathetic. Science. 2016;354(6314):893–7.
Yoshimura N. Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder. Prog Neurobiol. 1999;57(6):583–606.
Fowler CJ, Griffiths D, de Groat WC. The neural control of micturition. Nat Rev Neurosci. 2008;9(6):453–66.
Michel MC, Chapple CR. Basic mechanisms of urgency: roles and benefits of pharmacotherapy. World J Urol. 2009;27(6):705–9.
Panicker JN, Fowler CJ. The bare essentials: uro-neurology. Pract Neurol. 2010;10(3):178–85.
Tyagi P, Thomas CA, Yoshimura N, et al. Investigations into the presence of functional Beta1, Beta2 and Beta3-adrenoceptors in urothelium and detrusor of human bladder. Int Braz J Urol. 2009;35(1):76–83.
D’Amico SC, Collins WF 3rd. External urethral sphincter motor unit recruitment patterns during micturition in the spinally intact and transected adult rat. J Neurophysiol. 2012;108(9):2554–67.
Griffiths D, Tadic SD. Bladder control, urgency, and urge incontinence: evidence from functional brain imaging. Neurourol Urodyn. 2008;27(6):466–74.
de Groat WC, Araki I, Vizzard MA, et al. Developmental and injury induced plasticity in the micturition reflex pathway. Behav Brain Res. 1998;92(2):127–40.
Leng WW, Chancellor MB. How sacral nerve stimulation neuromodulation works. Urol Clin North Am. 2005;32(1):11–8.
Yoshiyama M, de Groat WC. Supraspinal and spinal alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid and N-methyl-D-aspartate glutamatergic control of the micturition reflex in the urethane-anesthetized rat. Neuroscience. 2005;132(4):1017–26.
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Panicker, J.N. (2019). Overview of Neural Control of Bladder Storage and Voiding. In: Liao, L., Madersbacher, H. (eds) Neurourology. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7509-0_6
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DOI: https://doi.org/10.1007/978-94-017-7509-0_6
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