Zusammenfassung
Laborwerte älterer Menschen sollten in Kenntnis der altersspezifischen Referenzwerte interpretiert werden. Die Nierenfunktion wird grundsätzlich anhand einer Formelclearance (z. B. CKDEpi) und nicht an der numerischen Größe des Serumkreatinins beurteilt. Zusätzlich werden bei der akuten Nierenschädigung und anderen Einschränkungen der Nierenfunktion Urinparameter herangezogen. Eine sinnvolle Analytik zur Ursachenklärung einer Nierenkrankheit und sekundärer Komplikationen wird vorgestellt. Grundsätzlich gilt, dass nicht die Laborwerte, sondern ältere Patienten behandelt werden.
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Literatur
Becker GJ, Garigali G, Fogazzi GB (2016) Advances in urine microscopy. Am J Kidney Dis 67(6):954–964
Calsolaro V, Niccolai F, Pasqualetti G, Tognini S, Magno S, Riccioni T, Bottari M, Caraccio N, Monzani F (2019) Hypothyroidism in the elderly: who should be treated and how? J Endocr Soc 3(1):146–158
Cavalieri TA, Chopra A, Bryman PN (1992) When outside the norm is normal: interpreting lab data in the aged. Geriatrics 47(5):66–70
Cavanaugh C, Perazella MA (2019) Urine sediment examination in the diagnosis and management of kidney disease: core curriculum 2019. Am J Kidney Dis 73(2):258–272
Chao CT, Tsai HB, Wu CY, Lin YF, Hsu NC, Chen JS, Hung KY (2015) The severity of initial acute kidney injury at admission of geriatric patients significantly correlates with subsequent in-hospital complications. Sci Rep 5:13925
Chou YH, Lu FP, Chen JH, Wen CJ, Lin KP, Chou YC, Wu MC, Chen YM (2021) Restoration of dysnatremia and acute kidney injury benefits outcomes of acute geriatric inpatients. Sci Rep 11(1):20097
Cortes-Penfield NW, Trautner BW, Jump RLP (2017) Urinary tract infection and asymptomatic bacteriuria in older adults. Infect Dis Clin North Am 31(4):673–688
Djukic M, von Arnim CAF (2021) B vitamins in geriatrics – what to determine, what to replace? Dtsch Med Wochenschr 146(3):152–156
Don BR, Sebastian A, Cheitlin M, Christiansen M, Schambelan M (1990) Pseudohyperkalemia caused by fist clenching during phlebotomy. N Engl J Med 322(18):1290–1292
Fleisher LA (2001) Routine laboratory testing in the elderly: is it indicated? Anesth Analg 93(2):249–250
Forman Daniel E, de Lemos James A, Shaw Leslee J, Reuben David B, Lyubarova R, Peterson Eric D, Spertus John A, Zieman S, Salive Marcel E, Rich Michael W (2020) Cardiovascular biomarkers and imaging in older adults. J Am Coll Cardiol 76(13):1577–1594
Grolleau-Julius A, Ray D, Yung RL (2010) The role of epigenetics in aging and autoimmunity. Clin Rev Allergy Immunol 39(1):42–50
Hafer C, Kielstein JT (2011) Akutes Nierenversagen. Der Nephrologe 6(2):120–127
Heart Protection Study Collaborative G (2011) Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20,536 high-risk individuals: a randomised controlled trial. Lancet 378(9808):2013–2020
Iglesias P, Bajo MA, Selgas R, Diez JJ (2017) Thyroid dysfunction and kidney disease: An update. Rev Endocr Metab Disord 18(1):131–144
Ketteler M, Schlieper G (2014) CKD-MBD beim betagten Patienten. Der Nephrologe 9(1):26–32
Khow KS, Lau SY, Li JY, Yong TY (2014) Diuretic-associated electrolyte disorders in the elderly: risk factors, impact, management and prevention. Curr Drug Saf 9(1):2–15
Lloyd SM, Stott DJ, de Craen AJ, Kearney PM, Sattar N, Perry I, Packard CJ, Briggs A, Marchbank L, Comber H, Jukema JW, Westendorp RG, Trompet S, Buckley BM, Ford I (2013) Long-term effects of statin treatment in elderly people: extended follow-up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). PLoS One 8(9):e72642
Meng QH, Wagar EA (2015) Pseudohyperkalemia: a new twist on an old phenomenon. Crit Rev Clin Lab Sci 52(2):45–55
Mishra N, Kammer GM (1998) Clinical expression of autoimmune diseases in older adults. Clin Geriatr Med 14(3):515–542
Palmer BF, Clegg DJ (2019) Physiology and pathophysiology of potassium homeostasis: core curriculum 2019. Am J Kidney Dis 74(5):682–695
Perazella MA (2015) The urine sediment as a biomarker of kidney disease. Am J Kindey Dis 66(5):748–755
Sterns RH (2020) Managing electrolyte disorders: order a basic urine metabolic panel. Nephrol Dial Transplant 35:1827–1830
Sztefko K, Szybowska P (2012) Interpretation of hormone levels in older patients: points for consideration. Int J Endocrinol 2012:712425
Weiss R, Meersch M, Pavenstädt H-J, Zarbock A (2019) Acute kidney injury. Deutsches Aerzteblatt Online
von Werder A, von Werder K (2018) Substitution with thyroid hormones in the elderly: goals and risks. Internist (Berl) 59(10):1114–1118
Woolen SA, Shankar PR, Gagnier JJ, MacEachern MP, Singer L, Davenport MS (2019) Risk of nephrogenic systemic fibrosis in patients with stage 4 or 5 chronic kidney disease receiving a group II gadolinium-based contrast agent: a systematic review and meta-analysis. JAMA Intern Med 180(2):223–230
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© 2023 Der/die Autor(en), exklusiv lizenziert an Springer-Verlag GmbH, DE, ein Teil von Springer Nature
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Hafer, C., Elitok, S. (2023). Basis- und spezielle Labordiagnostik. In: Hoffmann, U., Pommer, W. (eds) Geriatrische Nephrologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-65648-8_5
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