Skip to main content
SpringerLink
Log in

Neue chirurgische Therapieverfahren der gastroösophagealen Refluxkrankheit und Hiatushernie

  • Chapter
  • First Online:
Benigne Ösophaguserkrankungen

  • 647 Accesses

Zusammenfassung

Potenzielle unerwünschte Wirkungen der PPI-Therapie wie auch nicht immer zufriedenstellende Ergebnisse der etablierten Operationsmethoden führen aktuell zu steigendem Interesse an neuen chirurgischen Therapieverfahren zur Refluxtherapie. Die Technik und Ergebnisse der magnetische Verstärkung (LINX®) sowie der elektrische Stimulation (EndoStim® St. Louis, USA) des unteren ösophagealen Sphinkters werden dargestellt und diskutiert. Beide Verfahren sind wenig invasiv, prinzipiell reversibel und mit ermutigenden mittelfristigen Ergebnissen verbunden. Allerdings wird die Technik der elektrischen Stimulation gegenwärtig vom Hersteller nicht mehr angeboten. Es wird damit eine erweiterte Indikation zur chirurgischen Therapie der gastroösophagealen Refluxkrankheit angenommen. Dies birgt jedoch in Kombination mit der technischen Einfachheit der Verfahren das Risiko inadäquater Indikationen. Zur Gewinnung belastbarer Langzeitergebnisse wird die Etablierung eines verpflichtenden Registers vorgeschlagen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 99.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Literatur

  • Alicuben ET, Bell RCW, Jobe BA3, Buckley FP 3rd, Daniel Smith C, Graybeal CJ, Lipham JC (2018) Worldwide experience with erosion of the magnetic sphincter augmentation device. J Gastrointest Surg 22(8):1442–1447. https://doi.org/10.1007/s11605-018-3775-0. (Epub 2018 Apr 17)

  • Asti E, Aiolfi A, Lazzari V, Sironi A, Porta M, Bonavina L3 (2018) Magnetic sphincter augmentation for gastroesophageal reflux disease: review of clinical studies. Updates Surg 70(3):323–330. https://doi.org/10.1007/s13304-018-0569-6. (Epub 2018 Jul 18)

  • Berguer R, Stiegmann GV, Yamamoto M, Kim J, Mansour A, Denton J, Norton LW, Angelchik JP (1991) Minimal access surgery for gastroesophageal reflux: laparoscopic placement of the Angelchik prosthesis in pigs. Surg Endosc 5(3):123–126

    Article  CAS  PubMed  Google Scholar 

  • Boeckxstaens GE (2007) Review article: the pathophysiology of gastro-oesophageal reflux disease. Aliment Pharmacol Ther 26(2):149–160

    Article  CAS  PubMed  Google Scholar 

  • Bonavina L, DeMeester T, Fockens P et al (2010) Laparoscopic sphincter augmentation device eliminates reflux symptoms and normalizes esophageal acid exposure: one- and 2-year results of a feasibility trial. Ann Surg 252:857–862

    Article  PubMed  Google Scholar 

  • Bonavina L, Saino G, Bona D, Sironi A, Lazzari V (2013) One hundred consecutive patients treated with magnetic sphincter augmentation for gastroesophageal reflux disease: 6 years of clinical experience from a single center. J Am Coll Surg 217(4):577–585. https://doi.org/10.1016/j.jamcollsurg.2013.04.039 (Epub 2013 Jul 12)

    Article  PubMed  Google Scholar 

  • Broeders JA, Mauritz FA, Ahmed Ali U et al (2010) Systematic review and meta-analysis of laparoscopic Nissen (posterior total) versus Toupet (posterior partial) fundoplication for gastro-oesophageal reflux disease. Br J Surg 97(9):1318–1330

    Article  CAS  PubMed  Google Scholar 

  • Crookes PF (2006) Physiology of reflux disease: role of the lower esophageal sphincter. Surg Endosc 20(Suppl 2):462–466 (Epub 2006 Mar 23)

    Article  PubMed  Google Scholar 

  • DeMeester TR, Bonavina L, Abertucci M (1986) Nissen fundoplication for gastroesophageal reflux disease. Evaluation of primary repair in 100 consecutive patients. Ann Surg 204:19

    Google Scholar 

  • DeMeester TR, Stein HJ (1992) Minimizing the side effects of antireflux surgery. World J Surg 16:3354

    Google Scholar 

  • Dent J (2011) Barrett’s esophagus: a historical perspective, an update on core practicalities and predictions on future evolutions of management. J Gastroenterol Hepatol 26(Suppl 1):11–30

    Article  PubMed  Google Scholar 

  • Dickman R, Maradey-Romero C, Gingold-Belfer R, Fass R (2015) Unmet needs in the treatment of gastroesophageal reflux disease. J Neurogastroenterol Motil 21:309–319

    Article  PubMed  PubMed Central  Google Scholar 

  • Dyer R, Rogers WE, Penn SR, Glass TA (1984) Intra-abdominal migration of the Angelchik antireflux prosthesis. South Med J 77(3):384–386

    Article  CAS  PubMed  Google Scholar 

  • Fein M, Bueter M, Thalheimer A (2008) Chirurg. https://doi.org/10.1007/s00104-008-1532-8

  • Feussner H, Wilhelm D (2013) Antirefluxoperationen. Chirurg 84:339. https://doi.org/10.1007/s00104-012-2385-8

    Article  CAS  Google Scholar 

  • Finks JF, Wei Y, Birkmeyer JD (2006) The rise and fall of antireflux surgery in the United States. Surg Endosc 20:1698–1701

    Article  PubMed  Google Scholar 

  • Fuchs KH, Musial F, Ulbricht F, Breithaupt W, Reinisch A, Babic B, Fuchs H, Varga G (2017) Foregut symptoms, somatoform tendencies, and the selection of patients for antireflux surgery. Dis Esophagus 30(7):1–10. https://doi.org/10.1093/dote/dox022

    Article  CAS  PubMed  Google Scholar 

  • Fuchs KH (2005) Konventionelle und minimal-invasive chirurgische Therapie der gastroösophagealen Refluxkrankheit. Chirurg 76:370–378. https://doi.org/10.1007/s00104-004-0954-1

    Article  PubMed  Google Scholar 

  • Funk LM, Kanji A, Melvin WS, Perry KA (2014) Elective antireflux surgery in the US: an analysis of national trends in utilization and inpatient outcomes from 2005 to 2010. Surg Endosc 28:1712–1719. https://doi.org/10.1007/s00464-013-3380-y

    Article  PubMed  Google Scholar 

  • Galmiche JP, Zerbib F (2013) Bruley des Varannes S: Treatment of GORD: three decades of progress and disappointments United European Gastroenterology Journal 1(3):140–150. https://doi.org/10.1177/2050640613484021

    Article  Google Scholar 

  • Ganz RA (2015) Long-term outcomes of patients receiving a magnetic sphincter augmentation device for gastroesophageal reflux. Clin Gastroenterol Hepatol. https://www.ncbi.nlm.nih.gov/pubmed/26044316

  • Ganz RA, Peters JH, Horgan S, Bemelman WA, Dunst CM, Edmundowicz SA, Lipham JC, Luketich JD, Melvin WS, Oelschlager BK, Schlack-Haerer SC, Smith CD, Smith CC, Dunn D, Taiganides PA (2013) Esophageal sphincter device for gastroesophageal reflux disease. N Engl J Med 368(8):719–727. https://doi.org/10.1056/NEJMoa1205544

    Article  CAS  PubMed  Google Scholar 

  • Ganz RA (2016) A review of new surgical and endoscopic therapies for gastroesophageal reflux disease. Gastroenterol Hepatol 12(7):424–431

    Google Scholar 

  • Harnsberger CR, Broderick RC, Fuchs HF, Berducci M, Beck C, Gallo A, Jacobsen GR, Sandler BJ, Horgan S (2015) Magnetic lower esophageal sphincter augmentation device removal. Surg Endosc 29:984–986

    Article  PubMed  Google Scholar 

  • Kelly JJ, Watson DI, Chin KF et al (2007) Laparoscopic Nissen fundoplication: clinical outcomes at 10 years. J Am Coll Surg 205:570–575

    Article  PubMed  Google Scholar 

  • Kuckelman JP, Phillips CJ, Derickson MJ et al (2018) Esophageal magnetic sphincter augmentation as a novel approach to post-bariatric surgery gastroesophageal reflux disease. Obes Surg 8:3080. https://doi.org/10.1007/s11695-018-3292-y

    Article  Google Scholar 

  • Labenz J et al (2018) LESS-GERD registry. Gastroenterology 152(5):470

    Article  Google Scholar 

  • Labenz J, Chandrasoma PT, Knapp LJ, DeMeester TR (2018) Proposed approach to the challenging management of progressive gastroesophageal reflux disease. World J Gastrointest Endosc 10(9): 175–183. https://doi.org/10.4253/wjge.v10.i9.175. (Epub 2018 Sep 16)

  • Leonardi KH, Lee ME, El-Kurd, MF, Ellis FH (1977) An experimental study of the effectiveness of various antireflux operations. Ann Thorac Surg 24(3):215–222

    Google Scholar 

  • Lipham JC, Taiganides PA, Louie BE, Ganz RA, DeMeester TR (2015) Safety analysis of first 1000 patients treated with magnetic sphincter augmentation for gastroesophageal reflux disease. Dis Esophagus 28(4):305–311. https://doi.org/10.1111/dote.12199. (Epub 2014 Mar 11)

  • Louie BE, Farivar AS, Shultz D et al (2014) Short-term outcomes using magnetic sphincter augmentation versus Nissen fundoplication for medically resistant gastroesophageal reflux disease. Ann Thorac Surg 98:498–504

    Article  PubMed  Google Scholar 

  • Nieponice A, Borbely Y, Rodriguez L, Schulz HG et al (2016) EndoStim® LES stimulation therapy improves GERD in patients with laparoscopic sleeve gastrectomy. Surg Endosc 30:130

    Google Scholar 

  • Patel NM, Feiler EM, Patel KJ (1984) Angelchik antireflux prosthesis–its usefulness and review of literature. Am J Gastroenterol 79(1):12–15

    CAS  PubMed  Google Scholar 

  • Reynolds, JL, Zehetner J, Wu P, Shah S, Bildzukewicz N, Lipham JC (2015) Laparoscopic magnetic sphincter augmentation vs laparoscopic Nissen fundoplication: a matched-pair analysis of 100 patients. J Am Coll Surg 221(1):123–128

    Google Scholar 

  • Riegler M, Schoppman SF, Bonavina L et al (2015) Magnetic sphincter augmentation and fundoplication for GERD in clinical practice: one-year results of a multicenter, prospective observational study. Surg Endosc 29:1123–1129

    Article  PubMed  Google Scholar 

  • Rodriguez L, Rodriguez P, Gómez B, Ayala JC et al (2012) Electrical stimulation therapy (EST) of the lower esophageal sphincter (LES) – emerging treatment for preventing GERD in achalasia patients treated with LES myotomy. Emerging Technology Poster, SAGES, San Diego.

    Google Scholar 

  • Rodriguez L, Rodriguez PA, Gómez B et al (2016) Electrical stimulation therapy of the lower esophageal sphincter is successful in treating GERD: long-term 3-year results. Surg Endosc 30(7):2666–2672

    Article  PubMed  Google Scholar 

  • Rodriguez L, Rodriguez P, Gómez B et al (2013) Electrical stimulation therapy of the lower esophageal sphincter is successful in treating GERD: final results of open-label prospective trial. Surg Endosc 27:1083–1092

    Article  PubMed  Google Scholar 

  • Rosetti, M (1963) Die operierte Speiseröhre. Thieme, Stuttgart

    Google Scholar 

  • Schwameis K1, Schwameis M, Zörner B, Lenglinger J, Asari R, Riegler FM, Schoppmann SF (2014) Modern GERD treatment: feasibility of minimally invasive esophageal sphincter augmentation. Anticancer Res 34(5):2341–2348

    Google Scholar 

  • Sheu EG, Nau P, Nath B et al (2015) A comparative trial of laparoscopic magnetic sphincter augmentation and Nissen fundoplication. Surg Endosc 29(3):505–509

    Article  PubMed  Google Scholar 

  • Siersema PD, Smout AJ, Conchillo JM et al (2013) Electrical stimulation therapy (EST) of the lower esophageal sphincter (LES) – an effective therapy for refractory GERD – interim results of an international multicenter trial. United European Gastroenterol J 1(supp 1):A411

    Google Scholar 

  • Skubleny D, Switzer NJ, Dang J et al (2017) LINX(R) magnetic esophageal sphincter augmentation versus Nissen fundoplication for gastroesophageal reflux disease: a systematic review and meta-analysis. Surg Endosc 31:3078–3084

    Article  PubMed  Google Scholar 

  • Smith CD, Ganz RA, Lipham JC, Bell RC, Rattner DW (2017) Lower esophageal sphincter augmentation for gastroesophageal reflux disease: the safety of a modern implant. J Laparoendosc Adv Surg Tech A. 27(6):586–591. https://doi.org/10.1089/lap.2017.0025 (Epub 2017 Apr 21)

    Article  PubMed  Google Scholar 

  • Stephan D, Attwood S, Labenz J, Willeke F (2018) EndoStim®-Therapie – eine neue minimal-invasive Technologie in der Antirefluxchirurgie. Chirurg 89(10):785–792. https://doi.org/10.1007/s00104-018-0706-2

    Article  CAS  PubMed  Google Scholar 

  • Subramanian C, Triadafilopoulos G (2015) Refractory gastroesophageal reflux disease. . Gastroenterology Report 3(1):41–53. https://doi.org/10.1093/gastro/gou061

    Article  PubMed  Google Scholar 

  • Tatum JM, Alicuben E, Bildzukewicz N et al (2018) Removing the magnetic sphincter augmentation device: operative management and outcomes. Surg Endosc. https://doi.org/10.1007/s00464-018-6544-y

    Article  PubMed  Google Scholar 

  • Varshney S, Kelly JJ, Branagan G, Somers SS, Kelly JM (2002) Angelchik prosthesis revisited. World J Surg 26(1):129–133 (Epub 2001 Nov 26)

    Article  PubMed  Google Scholar 

  • von Rahden BH, Scheurlen M, Filser J, Stein HJ, Germer CT (2012) Newly recognized side-effects of proton pump inhibitors. Arguments in favour of fundoplication for GERD? Chirurg 83(1):38–44. https://doi.org/10.1007/s00104-011-2173-x

  • Warren HF, Brown LM, Mihura M et al (2018) Factors influencing the outcome of magnetic sphincter augmentation for chronic gastroesophageal reflux disease. Surg Endosc 32:405. https://doi.org/10.1007/s00464-017-5696-5

    Article  PubMed  Google Scholar 

  • Zaninotto G, DeMeester TR, Schwizer W, Johansson KE, Cheng SC (1988) The lower esophageal sphincter in health and disease. Am J Surg 155(1):104–111

    Article  CAS  PubMed  Google Scholar 

Laienmedien

Download references

Author information

Authors and Affiliations

  1. Allgemein- und Viszeralchirurgie, Marienkrankenhaus Kassel, Kassel, Deutschland

    Johannes Heimbucher

Authors
  1. Johannes Heimbucher
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Johannes Heimbucher .

Editor information

Editors and Affiliations

  1. Klinik und Poliklinik für Viszeral-, Transplantations-, Thorax- und Gefäßchirurgie, Universitätsklinikum Leipzig, Leipzig, Germany

    Ines Gockel

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Heimbucher, J. (2021). Neue chirurgische Therapieverfahren der gastroösophagealen Refluxkrankheit und Hiatushernie. In: Gockel, I. (eds) Benigne Ösophaguserkrankungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-60455-7_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-60455-7_14

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-60454-0

  • Online ISBN: 978-3-662-60455-7

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation