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Labortechniken: PID, PKD, PGT, Time-lapse Imaging

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Die Gynäkologie

Part of the book series: Springer Reference Medizin ((SRM))

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Zusammenfassung

Unter den Labortechniken in der assistierten Reproduktion sind Methoden zur Erfassung des Implantationspotenzials von Eizellen und Embryonen von besonderer Bedeutung. Ziel ist hierbei nicht unbedingt eine höhere Schwangerschaftsrate, sondern vielmehr die Verkürzung des Zeitintervalls bis zum Eintritt einer intakten Schwangerschaft. Durch die Etablierung neuerer und kostengünstiger Verfahren zum Nachweis aller Chromosomen rückt die Präimplantationsdiagnostik (PID) zur Diagnose von Chromosomenfehlverteilungen, sogenannten Aneuploidien, wieder mehr in den Vordergrund. Der Nutzen der PID an Polkörpern oder Trophektodermzellen der Blastozyste wird derzeit in mehreren randomisierten Studien untersucht. Gleichzeitig wird die Kombination mit weiteren Labortechniken zunehmend diskutiert, da sich möglicherweise synergistische Effekte hinsichtlich der Durchführung der Biopsie von Trophektodermzellen und der Interpretation der Ergebnisse ergeben. Dieser Beitrag beleuchtet den aktuellen Stand der PID.

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Authors and Affiliations

  1. ilabcomm GmbH, St. Augustin, Deutschland

    Markus Montag

  2. green-ivf: Grevenbroicher Endokrinologie & IVF-Zentrum, Grevenbroich, Deutschland

    Christian Gnoth

Authors
  1. Markus Montag
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  2. Christian Gnoth
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Correspondence to Markus Montag .

Editor information

Editors and Affiliations

  1. Otto-von-Guericke-Universität Universitäts-Frauenklinik, Magdeburg, Deutschland

    Serban-Dan Costa

  2. Abt. Gynäkologie, Klinikum St. Marien Amberg Frauenklinik, Amberg, Deutschland

    Anton Scharl

  3. Abt. Gynäkol. Endokrinologie, Univ.Klinik für Frauenheilkunde, Bern, Schweiz

    Petra Stute

  4. Frauenklinik, Universität Ulm, Ulm, Baden-Württemberg, Deutschland

    Wolfgang Janni

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Montag, M., Gnoth, C. (2021). Labortechniken: PID, PKD, PGT, Time-lapse Imaging. In: Costa, SD., Scharl, A., Stute, P., Janni, W. (eds) Die Gynäkologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47329-0_33-1

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  • DOI: https://doi.org/10.1007/978-3-662-47329-0_33-1

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  • Print ISBN: 978-3-662-47329-0

  • Online ISBN: 978-3-662-47329-0

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