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In Vivo Wear of Highly Crosslinked Polyethylene in Total Knee Arthroplasty

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Tribology in Total Hip and Knee Arthroplasty

Abstract

The main causes for knee arthroplasty revision later than 5 years in the study by Sharkey et al. [42] were polyethylene wear and aseptic loosening. Polyethylene wear has become a concern in total knee arthroplasty (TKA), because it has been stated as the main cause for osteolysis [1]. The presence of polyethylene particles in the joint, which are phagocytised by macrophages and giant cells [2], causes the release of many proinflammatory interleukins, which activate the osteoclasts, the main responsible cells for osteolysis [4, 22, 24].

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Correspondence to Pedro Hinarejos Gomez .

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Gomez, P.H., Jurado, I.P. (2014). In Vivo Wear of Highly Crosslinked Polyethylene in Total Knee Arthroplasty. In: Knahr, K. (eds) Tribology in Total Hip and Knee Arthroplasty. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45266-6_6

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  • DOI: https://doi.org/10.1007/978-3-642-45266-6_6

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