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Virale Infektionen: DNA-Viren

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Pädiatrie

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Zusammenfassung

Adenoviren verursachen im Kindesalter Krankheiten der Atemwege und des Darms, aber auch Krankheiten der Harnwege, der Lymphorgane, kardiologische und neurologische Manifestationen werden beobachtet. Einige typische Krankheitsbilder können klinisch diagnostiziert werden.

Adenovirus-Infektionen werden nur von Mensch zu Mensch übertragen. Sie treten das ganze Jahr über auf, insbesondere mit gastroenteritischen Symptomen. Konjunktivale/pharyngeale Krankheiten kommen häufiger im Sommer, Infektionen der Atemwege häufiger im Winter vor.

Durch diaplazentar übertragene mütterliche neutralisierende Antikörper sind die meisten Kinder bis etwa zum 6. Lebensmonat vor klinisch schweren Manifestationen geschützt. Wenn Neugeborene und junge Säuglinge erkranken, verläuft die Infektion überwiegend sehr schwer. Die meisten Adenovirus-Infektionen treten zwischen dem 6. Lebensmonat und dem 5. Lebensjahr auf. Mit 5 Jahren haben 70–80 % der Kinder neutralisierende Antikörper gegen Typ 1 und 2 sowie 50 % gegen Typ 5.

Insgesamt sind Adenoviren für etwa 25 % der Atemwegsinfektionen und 10–15 % der gastrointestinalen Infektionen im Kindesalter verantwortlich.

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Author information

Authors and Affiliations

  1. Abt. für Kinder- und Jugendmedizin mit Neonatologie, St. Josefskrankenhaus, Sautierstr. 1, 79104, Freiburg, Deutschland

    Johannes Forster Prof. Dr. med.

  2. Universitätskinderklinik, Universitätsklinikum Würzburg, Josef-Schneider-Str. 2–11, 97080, Würzburg, Deutschland

    Hans Wolfgang Kreth Prof. Dr. med.

  3. Universitätsklinik für Kinder und Jugendliche, Universitätsklinikum Leipzig, Liebigstr. 20a, 04103, Leipzig, Deutschland

    Volker Schuster Prof. Dr. med.

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  1. Johannes Forster Prof. Dr. med.
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  2. Volker Schuster Prof. Dr. med.
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  3. Hans Wolfgang Kreth Prof. Dr. med.
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Editor information

Editors and Affiliations

  1. Zentrum für Kinder und Jugendmedizin, Universitätsklinikum Heidelberg, Heidelberg, Germany

    Georg F. Hoffmann

  2. Forschungsinstitut für Kinderernährung, Dortmund, Germany

    Michael J. Lentze

  3. Zentrum für Kinder- und Jugendmedizin, Universitätsmedizin Mainz, Mainz, Germany

    Jürgen Spranger

  4. Zentrum für Kinder- und Jugendmedizin, Universitätsmedizin Mainz, Mainz, Germany

    Fred Zepp

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Forster, J., Schuster, V., Kreth, H.W. (2014). Virale Infektionen: DNA-Viren. In: Hoffmann, G., Lentze, M., Spranger, J., Zepp, F. (eds) Pädiatrie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-41866-2_100

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  • DOI: https://doi.org/10.1007/978-3-642-41866-2_100

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